Warfarin interactions UW Flashcards

1
Q

CYP450 inhibitor effect on warfarin?

A

Incr. warfarin effect – > incr. bleeding risk

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2
Q

CYP450 inducers effect on warfarin?

A

Decr. warfarin effect (ie decr in efficacy)

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3
Q

tie kurie yra CYP450 inducers ,,nemazina” kraujavimo rizikos :) mazina warfarino efektyvuma

A

.

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4
Q

CYP450 inhibitor. Incr. warfarin effect – > incr. bleeding risk

………

Azole antifungals

Amiodarone

Cimetidine

Grapefruit juice

A

Antibiotics (metronidazole, macrolides)

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5
Q

CYP450 inhibitor.

Antibiotics (metronidazole, macrolides)

………..

Amiodarone

Cimetidine

Grapefruit juice

A

Azole antifungals

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6
Q

CYP450 inhibitor.

Antibiotics (metronidazole, macrolides)

Azole antifungals

…………

Cimetidine

Grapefruit juice

A

Amiodarone

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7
Q

CYP450 inhibitor.

Antibiotics (metronidazole, macrolides)

Azole antifungals

Amiodarone

………..

Grapefruit juice

A

Cimetidine

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8
Q

CYP450 inhibitor.
Antibiotics (metronidazole, macrolides)

Azole antifungals

Amiodarone

Cimetidine

………..

A

Grapefruit juice

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9
Q

CYP450 inducers. Decr. warfarin effect (ie decr in efficacy).

……..

Phenytoin

Phenobarbital

Rifampin

St. John’s wort

A

Carbamazepine

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10
Q

CYP450 inducers. Decr. warfarin effect (ie decr in efficacy).

Carbamazepine

………

Phenobarbital

Rifampin

St. John’s wort

A

Phenytoin

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11
Q

CYP450 inducers. Decr. warfarin effect (ie decr in efficacy).

Carbamazepine

Phenytoin

………

Rifampin

St. John’s wort

A

Phenobarbital

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12
Q

CYP450 inducers. Decr. warfarin effect (ie decr in efficacy).

Carbamazepine

Phenytoin

Phenobarbital

………

St. John’s wort

A

Rifampin

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13
Q

CYP450 inducers. Decr. warfarin effect (ie decr in efficacy).

Carbamazepine

Phenytoin

Phenobarbital

Rifampin

…….

A

St. John’s wort (jonazole)

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14
Q

warfarin + Antibiotics (metronidazole, macrolides)

A

CYP450 inhibitor. Incr. warfarin effect – > incr. bleeding risk

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15
Q

warfarin + Azole antifungals

A

CYP450 inhibitor. Incr. warfarin effect – > incr. bleeding risk

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16
Q

warfarin + Amiodarone

A

CYP450 inhibitor. Incr. warfarin effect – > incr. bleeding risk

17
Q

warfarin + Cimetidine (antihist H2)

A

CYP450 inhibitor. Incr. warfarin effect – > incr. bleeding risk

18
Q

warfarin + Grapefruit juice

A

CYP450 inhibitor. Incr. warfarin effect – > incr. bleeding risk

19
Q

warfarin + Carbamazepine

A

CYP450 inducers. Decr. warfarin effect (ie decr in efficacy).

20
Q

warfarin + Phenytoin

A

CYP450 inducers. Decr. warfarin effect (ie decr in efficacy).

21
Q

warfarin + Phenobarbital

A

CYP450 inducers. Decr. warfarin effect (ie decr in efficacy).

22
Q

warfarin + Rifampin

A

CYP450 inducers. Decr. warfarin effect (ie decr in efficacy).

23
Q

warfarin + St. John’s wort

A

CYP450 inducers. Decr. warfarin effect (ie decr in efficacy).