Warfarin interactions UW Flashcards
CYP450 inhibitor effect on warfarin?
Incr. warfarin effect – > incr. bleeding risk
CYP450 inducers effect on warfarin?
Decr. warfarin effect (ie decr in efficacy)
tie kurie yra CYP450 inducers ,,nemazina” kraujavimo rizikos :) mazina warfarino efektyvuma
.
CYP450 inhibitor. Incr. warfarin effect – > incr. bleeding risk
………
Azole antifungals
Amiodarone
Cimetidine
Grapefruit juice
Antibiotics (metronidazole, macrolides)
CYP450 inhibitor.
Antibiotics (metronidazole, macrolides)
………..
Amiodarone
Cimetidine
Grapefruit juice
Azole antifungals
CYP450 inhibitor.
Antibiotics (metronidazole, macrolides)
Azole antifungals
…………
Cimetidine
Grapefruit juice
Amiodarone
CYP450 inhibitor.
Antibiotics (metronidazole, macrolides)
Azole antifungals
Amiodarone
………..
Grapefruit juice
Cimetidine
CYP450 inhibitor.
Antibiotics (metronidazole, macrolides)
Azole antifungals
Amiodarone
Cimetidine
………..
Grapefruit juice
CYP450 inducers. Decr. warfarin effect (ie decr in efficacy).
……..
Phenytoin
Phenobarbital
Rifampin
St. John’s wort
Carbamazepine
CYP450 inducers. Decr. warfarin effect (ie decr in efficacy).
Carbamazepine
………
Phenobarbital
Rifampin
St. John’s wort
Phenytoin
CYP450 inducers. Decr. warfarin effect (ie decr in efficacy).
Carbamazepine
Phenytoin
………
Rifampin
St. John’s wort
Phenobarbital
CYP450 inducers. Decr. warfarin effect (ie decr in efficacy).
Carbamazepine
Phenytoin
Phenobarbital
………
St. John’s wort
Rifampin
CYP450 inducers. Decr. warfarin effect (ie decr in efficacy).
Carbamazepine
Phenytoin
Phenobarbital
Rifampin
…….
St. John’s wort (jonazole)
warfarin + Antibiotics (metronidazole, macrolides)
CYP450 inhibitor. Incr. warfarin effect – > incr. bleeding risk
warfarin + Azole antifungals
CYP450 inhibitor. Incr. warfarin effect – > incr. bleeding risk