Warfarin and NOAC Flashcards
1
Q
What is the mechanism of action
A
Antagonise actions of vitamin K in blood clotting
2
Q
What is monitored and how often
A
INR, every 3 months once stable
3
Q
Target INR for VTE
A
2-3
4
Q
Target INR for recurrent VTE
A
3-4
5
Q
MHRA warnings
A
Hepatitis C antivirals can affect INR
Miconazole is a potent enzyme inhibitors and can increase anticoagulant effect
Calciphylaxis- painful skin rash
6
Q
What is the antidote for warfarin
A
Phytomenadione
7
Q
What do you do to warfarin before elective surgery
A
Stop 5 days before
Oral antidote if INR is >1.5
Restart on evening or next day
8
Q
High risk of bleeding with surgery what di you do to warfarin
A
Start LMWH 48 hours after surgery
9
Q
Warfarin counselling points
A
Yellow book Anticoagulant alert card Report any signs of bleeding Painful red rash Tell any health care professional Avoid cranberry juice
