Wang Flashcards
Testicular Masses vs Scrotal masses
Testicular masses: painless, do not transilluminate, malignant
Scrotal masses: painful, transilluminate, benign
Penile anatomy
Corpus cavernosum= erectile tissue
Corpus spongiosum= contains urethra
Tunica Albuginea= CT that surround erectile tissue
Current recommendations regarding circumcision?
Not enough evidence to make it standard procedure
Seminal vesicles?
Continuation of the vas deferens. Contributes 70% of semenal fluids
What hormones are necessary to stimulate spermatogenesis?
LH -> Testicles -> Testosterone + FSH -> spermatogenesis
Leukoplakia of the shlong
Scaly white patches. Need biopsy!
Bowens Disease
Thick, scaly, horny, pinkish brown intraepidermal pre-cancerous lesions
Two types of inflammation of the foreskin
Phimosis- cannot retract foreskin
Paraphimosis- cannot move foreskin foreward
Congenital abnormalities of urethra
Hyposadius- urethra on ventral surface of wang
Episadius- urethra on dorsal surface of wang
Priapism?
Non-erotic, painful sustained erection. Usually self-resolves within a few hours. Unknown etiology.
Peyronie’s disease
Plaque on the corpus cavernosum that causes a curvature in the erection. Sometimes they look like figure eights (jk). Unknown etiology, usually self-resolve.
M/C location for penile cancer?
Glans and foreskin
Ectopic testi location
Testi descends into the perineum, femoral area, inguinal area.
Testicular torsion prognosis?
80% good prognosis if surgically repaired within 6-8 hours of onset. If not taken care of can lead to atrophy and hormonal issues.
Lifting of testi and testicular torsion vs epididymitis
Lifting twisticle causes increase in pain
Lifting testi with epididymitis decreases pain
Hydrocele definition and age range
Fluid in sheath that surround testicles. Often painless and will transluminate. M/C in older men.
Varicocele- definition and age range
Blood backs up in the spermatic veins d/t faulty venous valves. Does not transilluminate. M/C younger men. Treatment is usually just supporting the testis.
Causes of orchitis
Bacterial infection or mumps virus. Can lead to atrophy and decreased hormone production.
What is the m/c cancer in males 15-35? Dx test? Tx?
Testicular cancer. Dx with US, usually also take Chx x-ray and abdominal CT. Treatment is orchectomy with surrounding lymph nodes.
Size of the average prostate?
4cm
Two types of prostatitis and their subtypes if there are any? Associated microorganisms and Dx tests
Acute bacterial prostatitis- usually E. Coli
Chronic Prostatitis: Bacterial (ureaplsma urealyticum). Non-bacterial (unknown etiology)
PSA levels, WBC in urine, ^ pH of prostatic fluid.
Prostadynia?
Prostatitis symptoms without infection or inflammation. Finesteride (BPH med) may help. May be d/t MSK spasm or nerve entrapment.
Pudendal nerve entrapment. Locations of entrapment?
Dx of exclusion.
- B/t sacrospinous and sacrotuberous ligs
- B/t falciform ligament of sacrotuberous lig
- In obturator fascia
Etiology of BPH. Who is at risk? Findings on DRE?
Decrease testosterone with increase estorogen and increased sensitivity of prostate to DHT causes BPH.
African American men high risk.
Soft and boggy DRE.
Does BPH increase risk of cancer?
No
At what age should you start DRE?
50
What produces PSA?
Prostate capsule and periurethral glands
What PSA values indicate you shoulder refer your patient?
4-10 ng/mL with abnormal DRE
>10 ng/mL
Treatment of BPH?
Finesteride 5 alpha reductase inhibitors (prevents production of DHT) Alpha blockers (relax smooth muscles) TURP Saw palmetto (weak evidence)
What symptoms are considered male sexual dysfunction?
Decreased libido
Ejaculatory disturbances
Erectile dysfunction
What is ADAM? Sx? Dx tests?
Androgen Decline in Aging Men
Mood changes, atrophy, osteoporosis, cognitive changes
Tests: testosterone levels
DRE findings in prostate cancer? Other test? Survival rate?
Rock hard pebble feel
Tests: PSA, 12 point biopsy, TRUS
80-90% 10 year survival rate when no metastsis. 10-15% 10 year survival rate when there’s mets.
What three hormones does the kidney produce?
Calcitrol (active V-D), Renin, EPO
When kidney function drops to what percentage is kidney replacement of some kind necessary (organ transplant or dialysis?)?
10-15%
M/C causes of kidney disease?
DM and/or HTN
What are the 4 types of glomerulonephritis?
Autoimmune (IgA kidney, SLE, Good Pasture’s syndrome)
Infection (post-strep, bacterial endocarditis, HIV)
Sclerotic disease (SLE, DM, glomerulosclerosis)
Inherited (PCKD)
Membranous neuropathy is another cause, often idiopathic
Constant vs intermittent urinary symptoms
Constant= infx Intermittent= obstruction
What conditions lead to increased urinary output? Decreased?
DM/I, diuretics, excess fluids
Obstructions, anxiety, neurogenic, extrinsic compression
Symptoms of obstructive voiding
Post-void dribble, decrease force, hesitancy, intermittancy
What is a sensitive test for proteinuria?
Albumin:creatinine ratio
How do you diagnose proteinuria? What does severe proteinuria usually indicate?
Retest 1-2 weeks after first positive test.
Severe glomerulonephritis
What condition(s) are associated with microscopic hematuria? Macroscopic hematuria?
Lower UTIs
Upper UTIs
What must you assume hematuria indicates until proven otherwise?
Cancer
What is pseudohematuria?
Reddish urine d/t beet or berry consumption
Hematuria during onset, duration, or end of urination indicates
Onset- urethra or prostate
Throughout- kidney, ureter, bladder
End- bladder, prostate
What does SITT stand for?
Stone, infection, trauma, tumor
M/C causes of hematuria
Casts and what they indicate
Epithelial- AVN of tubules WBC- pyelonephritis RBC- glomerulonephritis Hyaline- normal or chronic kidney disease Waxy- severe kidney dz Granular- severe kidney dz Fatty- nephrotic syndrome
What test is more accurate than creatinine levels for determining kidney disease?
GFR. Creatinine levels can be influenced by a number of different factors.
Stages of Kidney disease
- Kidney damage with normal GFR
- Kidney damage with mild decrease in GFR
- Kidney damage with moderate decrease in GFR (anemia and bone problems)
- Kidney damage with severe decrease in GFR (kidney transplant or dialysis)
- Kidney failure (kidney transplant or dialysis)
Definition of chronic or recurrent kidney UTI
> 2 in 6 months
UTIs in kids
Girls- recurrent may indicate abnormality in UT
Boys- even one episode means there needs to be evaluation for abnormality of UT
What is the most common organism to cause UTI?
90-95% E. Coli
Sx of lower UTI and upper UTI
Lower: suprapubic pain, frequency, urgency, dysuria, macroscopic hematuria
Upper: fever, chills, aches, CVA pain, flank pain, odorous urine, macroscopic hematuria
Sx of pyelonephritis
M/C secondary to ascending UTI
Fever >102, chills, aches, N/V, tachycardia
Urinary Stones m/c in who?
Cracker men folk
Risk factor for urinary stones?
Prego Obese HTN DM Stress UT abnormalities Meds (thyroid, diuretics, antacids)
Size of stone and sx
Size of stone is not an indication of pain levels
Dx tests for urinary stones?
Hematuria (85%) Electrolyte levels Ca2+ Uric acid Oxalate Creatinine Phosphorus
X-ray and CT (more sensitive and specific)
Tx of urinary stone
MUST RULE OUT OBSTRUCTION and INFECTION
Stats on size of stones and passage
> 75% of stones will pass spontaneously
2mm pass in 8 days; 2-4mm pass in 12 days; 4mm pass in 22 days
<5mm 85% pass in 3 weeks
5mm refer to urologist
Treating hyperoxalaria
Mg2+ may prevent absorption of oxalate
Pyridoxine (B6) may prevent formation of oxalate
How is incontinence defined?
By the patient!
4 types of incontinence
Stress- coughing, sneezing, etc. Weak sphincter.
Urge- overactive detrusor muscle
Mix- both stress and urge
Overflow- paralysis of detrusor muscle
Causes of incontinence
Vaginal birth Lifting weights Estrogen deficiency BPH Pelvic organ prolapse Smoking DM Meds UTI
Tx of incontinence
Pelvic floor rehab
E-stim
Meds
Behavioral mods (drink less water, more trips to bathroom)
Pessaries/urethral barriers
Meds (anticholinergic, antispasmodics, trigs, Ca2+ blockers, bet agonists, estrogen)
Definition of interstitial cystitis
M/C in who?
Sx?
Aka Painful Bladder Syndrome
Women 90%
Mild pain, pressure and tenderness over bladder
Dx based on ruling out, etiology is unknown
Tx for interstitial cystitis
Avoid tomatoes, spicy foods, caffeine, citrus fruits, artificial sweeteners
M/C symptom of bladder cancer
Hematuria
Two types of bladder cancer and survival rate
Superficial 85% 5 year survival rate
Invasis 5% 2 year survival rate
M/C type of renal carcinoma
Renal adenocarcimona
50-70yo men
Often asymptomatic at first
What is paraneoplastic syndrome
Condition associated with renal cancer
Weight loss, decrease appetite, night sweats, HTN