W6: Skin & Temp, Pharmacol., Skin Infections etc Flashcards

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1
Q

Skin structure

A

EPIDERMIS:

s. corneum
s. lucidum
s. granulosum
s. spinosum
s. basale

DERMIS: vascl, + muscles

Subcut. tissue: fat

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2
Q

Flat circumscribed areas

A

Macule / Patch

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3
Q

Raised areas

A

Papule / Plaque

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4
Q

Palpable lesions

A

Nodule

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5
Q

Fluid filled lesions

A

Vesicle / Bullae

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6
Q

Pus filled lesions

A

Pustule / Abscess

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7
Q

Loss of epidermis + dermis

A

Erosion / Ulcer

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8
Q

Investigations

A

Charcoal swab - bacteria=> microscopy, culture

Viral Swab - PCR, throat swabs, eruptions,

Punch biopsy

Fungal scrapings - mycology

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9
Q

Systemic treatments

A

ImmSupp

RETINOIDS: vit A analogues, normalise keratinocyte funct., anti-inflamm + antiCa
!monitor LFT and triglycerides

BIOLOGICS

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10
Q

Skin Infections (Bacterial)

A

IMPETIGO: children, s. aureus, s. pyogenes; bullae
=> topical *fusidic acid etc.), Abx oral fluclox, erythromycin

ERSIPELAS:

CELLULITIS: “”,
=> IV Fluclox + benzylpenicillin
> Severe orbital cellulitis
OEDEMA, BLISTERS: erythemous, lower leg bilateral

LIPODERMATOSCLEROSIS: poor circulation, acute, bilateral, venous dis.
=> Tx venous disease + topical steroids

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11
Q

Skin Infection (Fungal)

A

TINEA (dermatophyte)
unilateral
=> terbinafine, clotrimazole, oral antifungal
> tinea manum, capitis, cruris, corporis

CANDIDIASIS
- flexures
-pustules 
=> nysastatin
=> emollient
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12
Q

Skin Infection (Viral)

A

VIRAL WARTS: hpv, children imm suppr.
=> cyrotherapy
=> wart paints }stimulate imm system

MOLLUSCUM CONTAGIOSUM: self-resolve, DNA pox virus
=> potassium hydrochloride: stim imm system

HERPES SIMPLEX: HSV1 + HSV2
herpres herpeticum: crusted, monomorphic, erosion+vesicles
=> ACICLOVIR
*herpes zooster, crusted papules + vesicles 2º dermatological reactivation = shingles

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13
Q

Skin infestations

A

Hx: backpacking, hostels, camp, nursing homes

*bilateral webspaces genital, feet+ankle; faecal matter = irritation = crusted scabies (imm suprr.)

=>Permethrin
=> household/contacts

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