W6: Skin & Temp, Pharmacol., Skin Infections etc Flashcards
Skin structure
EPIDERMIS:
s. corneum
s. lucidum
s. granulosum
s. spinosum
s. basale
DERMIS: vascl, + muscles
Subcut. tissue: fat
Flat circumscribed areas
Macule / Patch
Raised areas
Papule / Plaque
Palpable lesions
Nodule
Fluid filled lesions
Vesicle / Bullae
Pus filled lesions
Pustule / Abscess
Loss of epidermis + dermis
Erosion / Ulcer
Investigations
Charcoal swab - bacteria=> microscopy, culture
Viral Swab - PCR, throat swabs, eruptions,
Punch biopsy
Fungal scrapings - mycology
Systemic treatments
ImmSupp
RETINOIDS: vit A analogues, normalise keratinocyte funct., anti-inflamm + antiCa
!monitor LFT and triglycerides
BIOLOGICS
Skin Infections (Bacterial)
IMPETIGO: children, s. aureus, s. pyogenes; bullae
=> topical *fusidic acid etc.), Abx oral fluclox, erythromycin
ERSIPELAS:
CELLULITIS: “”,
=> IV Fluclox + benzylpenicillin
> Severe orbital cellulitis
OEDEMA, BLISTERS: erythemous, lower leg bilateral
LIPODERMATOSCLEROSIS: poor circulation, acute, bilateral, venous dis.
=> Tx venous disease + topical steroids
Skin Infection (Fungal)
TINEA (dermatophyte)
unilateral
=> terbinafine, clotrimazole, oral antifungal
> tinea manum, capitis, cruris, corporis
CANDIDIASIS - flexures -pustules => nysastatin => emollient
Skin Infection (Viral)
VIRAL WARTS: hpv, children imm suppr.
=> cyrotherapy
=> wart paints }stimulate imm system
MOLLUSCUM CONTAGIOSUM: self-resolve, DNA pox virus
=> potassium hydrochloride: stim imm system
HERPES SIMPLEX: HSV1 + HSV2
herpres herpeticum: crusted, monomorphic, erosion+vesicles
=> ACICLOVIR
*herpes zooster, crusted papules + vesicles 2º dermatological reactivation = shingles
Skin infestations
Hx: backpacking, hostels, camp, nursing homes
*bilateral webspaces genital, feet+ankle; faecal matter = irritation = crusted scabies (imm suprr.)
=>Permethrin
=> household/contacts
