W6 Colour Vision Flashcards

1
Q

What is the nature of light and what wavelength spectrum is it within?

A

Light has a dual nature composed of electro-magnetic wave and Particle nature.
Wavelength is 380-750nm

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2
Q

What is Monochromacy and how do they differentiate between colour?

A

A person with only one photopigment. Cannot make wavelength based discrimination of colour and instead uses brightness.

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2
Q

Principle of univariance

A

All information about its wavelength is lost.

When a photopigment receptor absorbs light, it does not encode the wavel

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3
Q

What is Trichromatic Theory?

A

States that people have 3 cone types with 3 different peak wavelength absorptions based on the principle of univarriance. Cones are colourblind.

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4
Q

What are cone photospins and rod photospins peak wavelenghts absorption and how is colour discriminated?

A

Cones: S M L
S = 420nm - short wl
M = 530nm - middle wl
L = 560nm - long wl
Rod photospins = 500nm
Wavelenght discrimination requires the comparison of two different photoreceptors. Additionally, different wavelengths of different intensities can produce the same amount of absorption and thus generate the same signal.

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5
Q

What is a metameter?

A

When colour of a monochromatic test light can be matched by using combinations of lights or pigments.
E.g checking for Jaundice

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6
Q

What are the limitations of trichromatic theory

A

Fails to account for the four unique colours = red, green, yellow and blue.
Edward Harold noted that there are colour combinations unseen = green/red and blue/yellow

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7
Q

What theory was proposed instead of the trichromatic theory?

A

Edward Harold proposed the opponent process theory to explain the existance of after images.

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8
Q

Trichromatic explain the photopigments and signalling for light?

A

Photopigment consists of a chromophore
chemical and an opsin (protein).
The chromophore in all photopigments
is retinal, a derivative of retinol.
Photon absorption by the chromophore
triggers the chemical phototransduction
cascade which results in visual transduction.

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9
Q

CIE colour specification system –
key points

A
  • Specifies relative amounts of primaries to make matches of colour samples.
  • CIE primaries are imaginary.
  • Any set of colour matching function can be converted to another set of real or imaginary functions.
  • Dominant wavelenght = principle wavelength of colour
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10
Q

What are the two colour vision deficiencies?

A

Congenital:
- Due to absence of one or more colour photopigments
Acquired:
- Developed after birth
- Due to pathology - usually unequal btw each eye due to different pathology development.

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11
Q

What are the types of Congenital?

A

Absence of one or more photopigments:
- Absence of erythrolabe photopigment =
Protanopia
- Absence of chlorolabe photopigment =
Deuteranopia
- Absence of cyanolabe pigment =
Tritanopia
- Absence of all cone photopigments = rod
monochromasy

Due to anomalous cone photopigments
- Protanomaly, deuteranomaly, tritanomaly

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12
Q

What visual defects are most common?

A
  • Deutans are most common followed by protans then tritans
  • Anomalous trichromats are more common than dichromats
  • Large variations exist across different ethnic groups
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13
Q

What are the type of inheritance of visual defects?

A
  • Protan and Duetan colour vision
    deficiencies are typically inherited as X
    linked recessive so nay more males express
    colour vision deficiencies than females (8%
    of males have a congenital colour vision
    deficiency, but only 0.5% of females)
  • Tritan colour vision deficiencies
    are typically inherited as
    autosomal dominant. Much
    rarer than deutan and protan
    in congenital forms.
    Not sex-linked.
    50% chance to be affected
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14
Q

Ananomolus trichromats

A

Anomalous Trichromats have 3
photopigments, but their colour vision is
abnormal
* The absorption spectrum of one
photopigment is displaced to an abnormal
position

General:
Can see colours, just perceived differently
* Problem with mixture of red and green
* May be unaware of any colour
deficiency

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15
Q

Deutanopia and propanopia

A

Can not distinguish red from green.
Deutranopia: Chlorolabe is missing (green cone opsin
Propanopia: vision past 545nm is monochromatic. erythralobe is missing (red)

16
Q

What are the necessary conditions for testing for colour vision?

A
  • Adequate and appropriate lighting
  • Best Corrected Vision (Near if required)
  • Each eye tested separately
  • 2-3 seconds permitted for a response
17
Q

What are the colour vision tests and give a brief description?

A
  1. Ishihara defects- Most common for inherited red-green defects
    – Screening for protan and deutan defects only
    – 98% sensitivity, 94% specificity
    – Has a diagnosis plate but not always accurate
  2. Farnsworth D-15 Dichotomous test– More accurately identifies blue- yellow and also red-green defects
  3. Farnworth Munsell – Hue matching test
18
Q

Ishihara test

A

5 types of plates – test plate, transforming,
disappearing, appearing and diagnostic

19
Q

Farnsworth D-15
Dichotomous Test

A

■ Arrangement test – Set of coloured discs that have to be arranged in correct order starting from the reference cap

■ The type (Protan, Deutan, Tritan) and severity of colour vision loss can be calculated
■ It cannot differentiate between dichromacy and anomalous trichromacy

■ Back surface of caps have numbers recorded on them and examiner records order of numbers