W3_Mood Disorders Flashcards
Bipolar, AD, OCD
What is bipolar disorder?
Bipolar disorder (manic depression) is a treatable medical illness marked by extreme changes in mood, thought, energy, and behaviour.
Bipolar disorder
a person’s mood can alternate between the “poles” mania (highs) and depression (lows).
This change in mood or “mood swing” can last for hours, days, weeks or even months
What are the different types of bipolar disorder?
**Bipolar l **Disorder
A distinct period of severe manic episode for at least a week with rapid shift of mood.
Bipolar ll Disorder
at least 1 hypomanic episode but has not had a full manic episode.
Cyclothmyia
numerous periods with manic and depressive symptoms not severe enough to meet criteria for major episodes.
Prevalence and course of Bipolar I and II
Lifetime: 0.6 to 0.8% (USA); 1.6% (Singapore)
Male to Female Ratio (1.1 : 1)
Men > manic episodes
Women > depressive episodes; > rapid cycling; > alcohol use.
Average age of onset = 20 years old
Chronic condition
15 times more likely to have complete suicide
60-70% of manic episodes occur before or after a depressive episode
Bipolar Mood disturbance period
Diagnostic criteria
what are the symptoms and how many?
During mood disturbance period
(3 or more of the following symptoms
- Inflated self-esteem/ grandiosity
- Decrease need of sleep
- More talkative
- Flight of ideas
- Distractibility
- Psychomotor agitation (Hypersexual)
- High risk behavior
What are the treatment options for Bipolar patients?
Mood stabilizers
Mood stabilizers include agents that treat mania while preventing manic relapse, and agents that treat bipolar depression while preventing depressive relapse.
List the various categories of Mood stabilizers and adjunctive therapy
-Mood Stabilizer: Lithium Carbonate
Anti-convulsants/ antiepileptics
Atypical Antipsychotics
Mood stabilizer:
Lithium Carbonate
Most popular/ effective mood stabilizer
1st drug to be FDA approved for treatment of manic episodes in bipolar disorder in 1970.
Significant side effect burden, poorly tolerated in at least 1/3 of treated pts
Narrow therapeutic window (0.4 to 1.0 mmol/L)
Changes in dietary sodium intake can affect Lithium levels
Fluid volume affects lithium levels may lead to increase in side effects, progressing to lethal Li toxicity
Therapeutic window for Lithium Carbonate
(0.4 to 1.0 mmol/L)
What are the patient education that you will provide for patients taking Lithium Carbonate?
- Do drink enough water as the drug is excreted through the urinary system
- Changes in dietary sodium intake can affect lithium levels.
Name some of the anti-convulsants used to treat Bipolar
Valporate,
Carbamazepine,
Lamotrigine
Name some of the adjunctive therapy used together with anticonvulsants for patients that shows signs of ………..
Antipsychotics are used in adjunctive therapy with anticonvulsants.
When patients show signs of irritability or aggression then we will use olanzapine and quetiapine,
Name some of the adjunctive therapy used together with anticonvulsants
Antipsychotics such as Olanzapine, Risperidone, Quetiapine, Aripiprazole,
Ziprasidone, Clozapine
remember the anti-“P”sychotics drugs ends with ~”P”ine, Done and zole
What are the lab-tests to be done before starting Lithium Carbonate?
(❤️🩸🫘🍘⚖️
- Full blood count (FBC) with differentials
Leukocytosis – benign - Renal function test, U/E/Cr
Renal impairment - Thyroid function test
Hypothyroidism - ECG If > 40yrs old or existing cardiac disease
- Cardiac malformation, neonatal hypothyroidism
- Weight (We do not want patient to gain weight)
- Exclude Pregnancy (contraindicated to patients who are pregnant, concerns of birth defects)
How frequent should we conduct Lithium monitoring for patients?
Serum Lithium level monitoring:
* Sample** 5-7 days** after initiation,
* Change in dose/formulation
* Introduction of interacting medication.
* Monitor 2 weekly in acute phase until stable, 3 to 6 monthly thereafter.
* Obtain sample at least 12 hrs after last dose
* Therapeutic range: 0.4 – 1.0mmol/L
If we are conducting Lithium Monitoring for the patient tomorrow morning at 9am, when should be the last dose of Lithium Carbonate?
Last dose: 8pm today
Do not serve the morning dose at 8am and obtain sample
Nursing interventions for Bipolar Disorder
1) Establish TNPR
Non-judgemental
Active listening
Explore with patients
Encourage patient to verbalize if they have the mood to live on.
2) Milieu Management
Set boundaries
Check environment (noise levels etc.)
un-obtrusive suicide monitoring
3) Medication administration and monitoring
Side effects of the drug, after 2-3 weeks
behavioral charting
check for hoarding
4) Ensuring Patient’s Safety
(prevent single room, 1-1 monitoring, prevent patient self-lock, increased monitoring every 15mins)
**5) Caring for Patient’s ADLs **
(Hygiene & I/O Charting)
List the various types of Anxiety Disorders
(all the Ds)
PD is not Parkinson Disease yea
1) Generalised Anxiety Disorder (GAD)
- Anxiolytics only in Panic stage.
2) Social Anxiety Disorder (SAD) = Social Phobia
3) Panic Disorder w/ wo agoraphobia - Pharm
4) Simple Phobia - Psycho
5) Obsessive Compulsive Disorder (OCD) Pharm+Psycho
6) Adjustment Disorder
Fear of Height
Acrophobia
Fear of Open Space
Agoraphobia
Fear of closed space
Claustrophobia
Fear of Strangers
Xenophobia
Fear of dirt and germs
Mysophobia
Fear of water
Hydrophobia