VULVAR INFECTIONS Flashcards
Condyloma Acuminatum
Etiology
: HPV
16, 18: aneuploid,
premalignant or malignant
lesions
6, 11: benign, euploid
lesions
Condyloma Acuminatum
Clinical Features
Raised & ragged lesions cauliflower lesions
(+) pruritus
(+) grows fast
spread by skin-to-skin contact
Condyloma Acuminatum
Diagnosis
EXCISION Biopsy
PATHOGNOMONIC: Koilocytes seen on cytology
Koilocytes - cells with
perinuclear halos)
Condyloma Acuminatum
Treatment
Electrocautery - in office
Cryotherapy
Chemical cautery - if lesion is thin
SMALL LESIONS: IMIQUIMOD (topical cream for small
multiple lesions)
Condyloma Acuminatum in a pregnant patient
Deliver CS if condyloma is so prolific
Baby might incur virus (laryngeal
papilloma)
In early pregnancy: Do not use chemical cauterizing drugs;
treat mechanically via excisions,
cauterization or cryotherapy
Herpes Genitalis
Describe lesion
Vesicles
Ulcers (vesicles that have ulcerated)
(+) painful
Herpes Genitalis
what is peculiar about this disease?
Recurrent & incurable STD
• 1st recurrence usually within 6 months
• May recur 4x in first year
Herpes Genitalis
Causative agent
Herpes Simplex
Virus Type 2 – resides in
dorsal root ganglia (S2, S3,
S4)
Before appearance of herpetic vesicles, what symptoms may arise first?
Sacroneuralgia vulvar burning tenderness pruritus inguinal adenopathy --> appear hours to 5 days before vesicle formation
What vulvar lesion causes tender inguinal lymphadenopathy
HSV 2
Herpes
HSV diagnosis
- PCR - most accurate and sensitive
- Tzanck smear (+) multinucleated giat cells
- viral culture or serologic testing
HSV Treatment
ACYCLOVIR (A mukhang 4)
400 mg
3x/day for 7-10
days
Daily suppression/prophylaxis: if >6 episodes/year (Acyclovir 400mg
orally BID)
Molluscum Contagiosum
Etiologic agent
Poxvirus
Molluscum Contagiosum
Mode of transmission
Asymptomatic
Molluscum Contagiosum
Lesion description
asymptomatic
Umbilicated papule
“water wart”