Vulvar and Ovarian Disease Flashcards

1
Q

cigarette paper epithelium

or figure 8 distribution

A

lichen sclerosus

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2
Q

lichen sclerosis increases risk of?

A

SCC

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3
Q

diagnostic for lichen sclerosus?

A

punch biopsy

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4
Q

multifocal lesions, raised/flat, usu. white (or other colors) on the vulva

A

vulvar intraepithelial neoplasia

premalignancy of the vulva

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5
Q

VIN related to HPV

and who gets it

A

VIN, usual type
combined VIN 2&3

younger women

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6
Q

VIN related to lichen sclerosis

and who gets it

A

VIN, differentiated

older women

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7
Q

presence of squamous cell atypia in the vagina w/o invasion

A

VaIN

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8
Q

asymptomatic or post-coital spotting or vaginal discharge

can be isolated or multifocal lesion, red, ulcerated, or white

A

VaIN

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9
Q

VaIN 1?

A

lower 1/3 of epithelium

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10
Q

VaIN 2?

A

lower 2/3 of epithelium

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11
Q

VaIN 3

A

more than 2/3 of epithelium

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12
Q

hx of VaIN screening?

A

cytologic smears & HPV testing every 4-6 mo. for 1-2 years

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13
Q

majority of vaginal cancers?

A

SCC

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14
Q

diagnosis of vaginal cancers?

A

colposcopy w/ biopsy preferred

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15
Q

most common ovarian cyst, size, and outcome

A

follicular cyst
3-8 cm
can resolve spontaneously w/in 1-2 mo.

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16
Q

corpus luteum cyst size, relationship to cycle, and outcome

A

3-11 cm
related to postovulatory phase of menses
regresses after 1-2 mo.

17
Q

theca lutein cyst characteristics (3)

A

seen with elevated hCG levels
usu. bilateral
filled w/ straw colored fluid

18
Q

most common ovarian cancer & characteristics (2)

A

epithelial serous
usu bilateral
>15 cm in diameter

19
Q

aggressive epithelial ovarian cancer

A

clear cell

20
Q

germ cell tumor prevalence, prognosis, & markers

A

most common

21
Q

most common germ cell tumor & presentation

A

dysgerminomas

mostly unilateral

22
Q

2nd most common germ cell tumor & characteristics (2)

A

immature teratoma
unilateral
produces a-FP

23
Q

what ovarian tumor secretes estrogen

A

granulosa cell

24
Q

diagnostics for ovarian cancer (4)

A

pelvis u/s
Ca 125
hCG
AFP

25
Q

3 unexpected assoc. w/ PCOS

A

acanthosis nigricans
metabolic syndrome
insulin resistance

26
Q

diagnostic criteria for PCOS (4)

A

2 out of 4:
ovulation disorders
chemical/biochem signs of hyperandrogenism
polycystic ovaries on US

27
Q

PCOS US findings (3)

A

> 12 follicles
2-9 mm diameter
string of pearls appearance

28
Q

white atrophic papules –> smooth white plaques on vulvar epithelium

A

lichen sclerosus