VTE 3 Flashcards

1
Q

tinzaparin dose?

A

175 anti-Xa IU/kg SC daily

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2
Q

Which of the following are preferred in renal insufficiency?
A. Argatroban 2 mcg/kg/min IV
B. Lepirudin 0.3 mg/kg IV

A

A

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3
Q

What is the correct dose for initial VTE treatment?
A. warfarin 10 mg in a pt with HF
B. Fondaparinux 7.5 mg SC in a pt that weighs 46 kg
C. Apixaban 10 mg po BID for the 1st 21 days
D. dabigatran 150 mg po BID

A

D

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4
Q
What is the correct MD for UFH?
A. 1000 units/ h
B. 3000 units/ h
C. 18 units/kg/min
D. 80 unit/kg/h
A

A

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5
Q

What is the correct dose for a pt with CrCl = 28?
A. Fondaparinux 5 mg SC in a pt with renal insufficiency
B. Enoxaparin 1.5 mg/kg SC daily
C. Enoxaparin 1 mg/kg SC daily
D. Rivaroxiban 15 mg po BID with food

A

C

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6
Q

When does maintenance therapy begin for pts being treated for a VTE?

A

one week after initial treatment began

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7
Q

What is the purpose of maintenance therapy?

A

to prevent another clot from forming

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8
Q

What should not be used while platelets are below 150 x10^9?

A

warfarin

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9
Q

How long does maintenance therapy last for a pt with a first time VTE and no coagulopathies?

A

3 months

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10
Q

How long does maintenance therapy last for pts with an unprovoked VTE and no coagulopathies?

A

3 months then eval risks vs. benefits for pts to receive longer term therapy

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11
Q

how long does maintenance therapy last in pts that have had a 2nd unprovoked VTE?

A

long-term therapy

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12
Q

how long are pts treated for VTE if they have a coagulopathy?

A

Lifelong

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13
Q

True or false. warfarin dosing adjustments are made on a monthly basis

A

false, weekly basis

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14
Q

warfarin adjustments should be made in increments of ______% of the total weekly dose

A

5-20%

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15
Q

how soon do you follow up with a pt on warfarin, after a dosage change?

A

1-2 weeks

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16
Q

how often do you monitor pts with a consistently stable INR?

A

every 12 weeks

17
Q

What is the purpose of prophylaxis treatment of VTE?

A

to prevent a clot from forming

18
Q

Prophylaxis treatment: Which is the correct dose?
A. Dalteparin 2500 units SC BID for low to moderate risk pts
B. Enoxaparin 40 mg SC q 12 h for a pt who just had knee replacement surgery
C. Fondaparinux 5 mg SC daily
D. Dabigatran 150 mg PO BID

A

D
Correct doses:
A. Dalteparin 2500 units SC daily for low to moderate risk pts
B. Enoxaparin 30 mg SC q 12 h for a pt who just had knee replacement surgery
C. Fondaparinux 2.5 mg SC daily
D. Dabigatran 150 mg PO BID

19
Q

[SATA] Prophylaxis treatment: Which is the correct dose?
A. UFH 5000 units SC q 8 h (high risk)
B. Desirudin 20 mg SC q 12 h up to 12 days before hip replacement surgery
C. Warfarin 5 mg po daily
D. fondaparinux 2.5 mg SC daily

A

A, C, D

B. correct dose. 15 mg (not 20 mg)

20
Q

Prophylaxis treatment: Which is the correct dose for Dalteparin?

A

2500 unitsSC daily (Lā€“> M risk)

2500 units SC BID or 5000 units SC (H risk)

21
Q

Prophylaxis treatment: Which is the correct dose for Enoxaparin?

A

40 mg SC daily

22
Q

Prophylaxis treatment for knee replacement surgery: Which is the correct dose for Enoxaparin?

A

30 mg SC q 12 h

23
Q

Prophylaxis treatment: Which is the correct dose for Fondaparinux?

A

2.5 mg SC daily

24
Q

Prophylaxis treatment: Which is the correct dose for Warfarin?

A

5 mg po daily (adjust based on INR)

25
Q

Prophylaxis treatment for knee replacement surgery: Which is the correct dose for Rivaroxiban?

A

10 mg po daily for 12 days after knee replacement surgery

26
Q

Prophylaxis treatment for hip replacement surgery: Which is the correct dose for Rivaroxiban?

A

10 mg po daily for 35 days after hip replacement surgery

27
Q

Prophylaxis treatment: Which is the correct dose for Dabigatran?

A

150 mg po bid

28
Q

Prophylaxis treatment: Which is the correct dose for Apixaban?

A

2.5 mg po BID

29
Q

Prophylaxis treatment: Which is the correct dose for Desiruidin?

A

15 mg SC q 12 h up to 12 days in pts undergoing elective hip replacement surgery