VTE 3 Flashcards
tinzaparin dose?
175 anti-Xa IU/kg SC daily
Which of the following are preferred in renal insufficiency?
A. Argatroban 2 mcg/kg/min IV
B. Lepirudin 0.3 mg/kg IV
A
What is the correct dose for initial VTE treatment?
A. warfarin 10 mg in a pt with HF
B. Fondaparinux 7.5 mg SC in a pt that weighs 46 kg
C. Apixaban 10 mg po BID for the 1st 21 days
D. dabigatran 150 mg po BID
D
What is the correct MD for UFH? A. 1000 units/ h B. 3000 units/ h C. 18 units/kg/min D. 80 unit/kg/h
A
What is the correct dose for a pt with CrCl = 28?
A. Fondaparinux 5 mg SC in a pt with renal insufficiency
B. Enoxaparin 1.5 mg/kg SC daily
C. Enoxaparin 1 mg/kg SC daily
D. Rivaroxiban 15 mg po BID with food
C
When does maintenance therapy begin for pts being treated for a VTE?
one week after initial treatment began
What is the purpose of maintenance therapy?
to prevent another clot from forming
What should not be used while platelets are below 150 x10^9?
warfarin
How long does maintenance therapy last for a pt with a first time VTE and no coagulopathies?
3 months
How long does maintenance therapy last for pts with an unprovoked VTE and no coagulopathies?
3 months then eval risks vs. benefits for pts to receive longer term therapy
how long does maintenance therapy last in pts that have had a 2nd unprovoked VTE?
long-term therapy
how long are pts treated for VTE if they have a coagulopathy?
Lifelong
True or false. warfarin dosing adjustments are made on a monthly basis
false, weekly basis
warfarin adjustments should be made in increments of ______% of the total weekly dose
5-20%
how soon do you follow up with a pt on warfarin, after a dosage change?
1-2 weeks
how often do you monitor pts with a consistently stable INR?
every 12 weeks
What is the purpose of prophylaxis treatment of VTE?
to prevent a clot from forming
Prophylaxis treatment: Which is the correct dose?
A. Dalteparin 2500 units SC BID for low to moderate risk pts
B. Enoxaparin 40 mg SC q 12 h for a pt who just had knee replacement surgery
C. Fondaparinux 5 mg SC daily
D. Dabigatran 150 mg PO BID
D
Correct doses:
A. Dalteparin 2500 units SC daily for low to moderate risk pts
B. Enoxaparin 30 mg SC q 12 h for a pt who just had knee replacement surgery
C. Fondaparinux 2.5 mg SC daily
D. Dabigatran 150 mg PO BID
[SATA] Prophylaxis treatment: Which is the correct dose?
A. UFH 5000 units SC q 8 h (high risk)
B. Desirudin 20 mg SC q 12 h up to 12 days before hip replacement surgery
C. Warfarin 5 mg po daily
D. fondaparinux 2.5 mg SC daily
A, C, D
B. correct dose. 15 mg (not 20 mg)
Prophylaxis treatment: Which is the correct dose for Dalteparin?
2500 unitsSC daily (Lā> M risk)
2500 units SC BID or 5000 units SC (H risk)
Prophylaxis treatment: Which is the correct dose for Enoxaparin?
40 mg SC daily
Prophylaxis treatment for knee replacement surgery: Which is the correct dose for Enoxaparin?
30 mg SC q 12 h
Prophylaxis treatment: Which is the correct dose for Fondaparinux?
2.5 mg SC daily
Prophylaxis treatment: Which is the correct dose for Warfarin?
5 mg po daily (adjust based on INR)
Prophylaxis treatment for knee replacement surgery: Which is the correct dose for Rivaroxiban?
10 mg po daily for 12 days after knee replacement surgery
Prophylaxis treatment for hip replacement surgery: Which is the correct dose for Rivaroxiban?
10 mg po daily for 35 days after hip replacement surgery
Prophylaxis treatment: Which is the correct dose for Dabigatran?
150 mg po bid
Prophylaxis treatment: Which is the correct dose for Apixaban?
2.5 mg po BID
Prophylaxis treatment: Which is the correct dose for Desiruidin?
15 mg SC q 12 h up to 12 days in pts undergoing elective hip replacement surgery
