Vocabulary Flashcards
absolute bioavailability
the bioavailability of a drug
product compared to the same drug in the form of a
rapidly administered IV solution.
absorption
the movement of the drug from the dosage
formulation into the blood.
abstracting services
services that locate and summarize
professional and scientific journal articles on specific
topIcs.
active transport
the movement of drugs from an area of
lower concentration to an area of higher concentration; cellular energy is required
acute condition
a sudden condition requiring immediate
treatment.
acute viral hepatitis
an inflammatory condition of the
liver caused by viruses.
additive
a drug that is added to a parenteral solution.
additive effects
the summation in effect when two drugs
with similar pharmacological actions are taken.
admission orders
the initial medications ordered when a
patient is admitted to the hospital.
admixture
the resulting solution when a drug is added
to a parenteral solution.
adverse drug effect/event/reaction
an unintended side effect of a medication that is negative or in some way injurious to a patient’s health; injury may be preventable in some cases but may be unpredictable and unavoidable in other cases.
agonists
drugs that activate receptors to accelerate or
slow normal cell function.
alimentary tract
the organs from the mouth to the anus.
aliquot
a portion of a mixture.
alveolar sacs (alveoli)
the small sacs in the lungs that transfer oxygen out of inspired air into the blood and carbon dioxide out of the blood and into air that will be exhaled.
ampules
sealed glass containers with an elongated neck
that must be snapped off before use.
analgesia
a state in which pain is not felt even though a
painful condition exists.
anaphylactic shockw
a potentially fatal hypersensitivity reaction producing severe respiratory distress and cardiovascular collapse.
androgens
male sex hormones.
anemia
a decrease in hemoglobin, or red blood cells.
anhydrous
without water molecules.
anions
negatively charged particles.
antagonists
drugs that bind with receptors but do not activate them. They block receptor action by preventing other drugs or substances from activating them.
anthelmintics
drugs that destroy worms.
antibiotic
a substance that harms or kills microorganisms like bacteria and fungi.
antibiotic therapy
a common home infusion service used for treating AIDS-related and other infections.
antidote
a drug that antagonizes the toxic effect of
another drug.
antihyperlipidemics
drugs that lower cholesterol and triglyceride levels.
antipyretic
reduces fever.
antitoxin
a substance that acts against a toxin in the body; also, a vaccine containing antitoxins, used to
fight disease.
antitussive
a drug that acts against a cough.
aqueous
water based.
arrest knob
the knob on a balance that prevents any
movement of the balance pans.
arrhythmia
an abnormal heart rhythm.
aseptic techniques
methods that maintain the sterile condition of products.
automated dispensing cabinet
an automated device that dispenses medications at the point-of-use.
automated filling machines
automated machines that fill and label pill bottles with correct quantities of ordered drugs.
auxiliary labels
labels regarding specific warnings, foods or medications to avoid, potential side effects, and other cautionary interactions.
bactericidal
bacteria killing.
bacteriostatic
bacteria inhibiting.
batching
preparation of large quantities of unit dose oral solutions/suspensions or small volume parenterals for future use.
bevel
an angled surface at the tip of a needle.
beyond-use date
a date assigned to compounded prescriptions beyond which the preparation should not be used.
bioavailability
the amount of an administered dose that reaches the general circulation and the rate at which this occurs.
biocompatibility
not irritating; does not promote infection or abscess.
bioequivalency
the comparison of bioavailability between two dosage forms.
biopharmaceutics
the study of the factors associated with drug products and physiological processes, and the resulting systemic concentrations of the drugs.
black box warning
information on a prescription drug’s product labeling calling attention to serious or life threatening risks.
blocker
another term for an antagonist drug, because antagonists block the action of neurotransmitters.
body surface area
a measure used for dosage that is calculated from the height and weight of a person and measured in square meters.
bronchodilators
a medication that decongests the bronchial tubes.
buccal
pouch between the cheek and teeth in the mouth.
buffer system
ingredients in a formulation designed to control the pH.
bulk compounding log
a record of medications that are compounded in the pharmacy for nonspecific patients. Information must include a list of all the ingredients, amounts used, manufacturer, lot numbers, and expiration dates of each specific ingredient.
calcium channel blockers
drugs that lower blood pressure by relaxing blood vessels.
calibrate
to set, mark, or check the graduations of a
measuring device.
cardiac cycle
the contraction and relaxation of the heart
that pumps blood through the cardiovascular system.
cations
positively charged particles.
central pharmacy
the main inpatient pharmacy in a hospital that has pharmacy satellites. It is the place where most of the hospital’s medications are prepared and stored.
certification
a legal document certifying that an individ-
ual meets certain objective standards, usually provided by a neutral professional organization.
Chapter <795>
regulations from USP-NF pertaining to compounding nonsterile preparations.
Chapter <797>
regulations from USP-NF pertaining to compounding sterile preparations.
chronic condition
a continuing condition that requires ongoing treatment for a prolonged period.
chyme
the semiliquid form of food as it enters the intes-
tinal tract.
cirrhosis
a chronic liver disease causing loss of function.
civil law
laws pertaining to wrongs to an individual.
clean room
area designed for the preparation of sterile
products.
close call
a medication safety event that had the potentil to cause harm but did not reach the patient.
closed formulary
a limited list of approved medications; a type of formulary that requires physicians to order only those medications on the formulary list; some exceptions may apply.
clotting factors
factors in the blood coagulation process.
CMS-1500 form
the standard form used by health-care providers to bill for services, including disease state management services.
CMS-10114 form
the standard form used by health-care providers to apply for a National Provider Identifier (NPI)
co-insurance
an agreement for cost-sharing between the insurer and the insured.
co-pay
the portion of the price of medication that the
patient is required to pay.
code cart
a locked cart of medications and other medi-
cal equipment designed for emergency use.
colloids
particles up to a hundred times smaller than
those in suspensions that are, however, likewise sus-
pended in a solution.
Combat Methamphetamine Epidemic Act (CMEA)
federal law that sets daily and monthly limits on OTC sale of pseudoephedrine and ephedrine.
combining vowel
a vowel used to connect the prefix, root word, or suffix parts of a term.
competent
being qualified and capable.
complexation
when two different molecules associate or
attach to each other.
compliance
doing what is required.
compounded sterile preparation (SP)
a compounded sterile dosage form.
compounding community pharmacy
pharmacies that specialize in providing compounding services but may also fill prescriptions for commercially available products and/or sell some over-the-counter products; some-times called hybrid pharmacies.
Compounding Record
a record of what actually happened when the preparation was compounded.
compression molding
a method of making suppositories in which the ingredients are compressed in a mold.
concentration
the strength of a solution as measured by the weight-to-volume or volume-to-volume of the substance being measured.
confidential
the requirement of health-care providers to
keep all patient information private among the patient, the patient’s insurer, and the providers directly involved in the patient’s care.
conjunctiva
the eyelid lining.
conjunctivitis
inflammation of the conjunctiva (eyelid
lining).
consultant pharmacist
develops and maintains an individual pharmaceutical plan for each long-term care patient.
contraceptive
device or formulation designed to prevent
pregnancy.
contracts
legal agreements that have duties associated with them.
controlled substance mark the mark (CII-CV)
that indicates the control category of a drug with a potential for abuse.
controlled substances
five groups of drugs identified by the 1970 Controlled Substances Act (CSA) as having the potential for abuse and whose distribution is therefore strictly controlled by five control schedules set forth in the CSA.
conversions
changing one unit of measure into another
so that both amounts are equal.
coring
when a needle damages the rubber closure of a
parenteral container causing fragments of the closure to fall into the container and contaminate its contents.
corticosteroid
hormonal steroid substances produced by
the cortex of the adrenal gland.
counting tray
a tray designed for counting pills.
CPOE
a system in which the physician or agent of the
physician enters orders directly into the hospital computer system.
criminal law
laws pertaining to a wrong to society.
Current Procedural Terminology codes (CPT codes)
identifiers used for billing MTM services.
DAW (dispense as written)
mechanism by which a prescriber may indicate that the brand product, not the equivalent generic, must be dispensed.
data
information that is entered into and stored in a
computer system.
database
a collection of information structured so that
specific information within it can easily be retrieved
and used.
days supply
the number of days the prescribed quantity
of medication will last when taken as directed.
DEA number
required on all controlled drug prescriptions; identifies the prescriber.
deductible
a set amount that must be paid by the patient
for each benefit period before the insurer will cover
additional expenses.
denominator
the bottom or right number in a fraction.
depot
the area in the muscle where a formulation is
injected during an intramuscular injection.
depth filter
a filter that can filter solutions being drawn
into or expelled from a syringe, but not both ways in
the same procedure.
dermatological
a product used to treat a skin condition.
diabetes mellitus
a condition in which the body does not
produce enough insulin or is unable to use it efficiently.
dialysis
movement of particles in a solution through
permeable membranes.
diastolic pressure
the blood pressure after the heart has
completed a pumping stroke.
diluent
a solvent that dissolves a freeze-dried lyophilized powder or dilutes a solution.
discharge pharmacy technician
a technician who specializes in outpatient pharmacy services that may be offered to patients when they are leaving the hospital.
disintegration
the breaking apart of a tablet into smaller pieces.
displacement
a drug that is bound to a plasma protein is removed when another drug of greater binding potential binds to the same protein.
disposition
a term sometimes used to refer to all of the
ADME processes together.
dissociation
when a compound breaks down and separates into smaller components.
dissolution
when the smaller pieces of a disintegrated
tablet dissolve in solution.
Distributive pharmacist
Makes sure long-term care patients receive the correct medications ordered
diuretics
drugs that increase the elimination of salts and
water through urination.
drip rate
the measurement for IV flow rate; the number
of drops per minute.
drip rounds
a process in which the pharmacy technician goes to specific nursing units to find out what IV drips will be needed later that day.
drop shipments
lower-volume, high-cost medications shipped on an as-need basis directly from the manufacturer and billed through the wholesaler.
drug-diet interactions
when elements of ingested nutrients interact with a drug and this affects the disposition of the drug.
drug recall
voluntary or involuntary removal of a drug product by the manufacturer; usually pertaining to a particular shipment or lot number.
drug resistance
the reduction of an antibiotic’s effectiveness.
dual co-pay
co-pays that have two prices: one for generic and one for brand medications.
dual marketing
status of medications like Plan B® that are classified as both prescription and OTC drugs.
DUR (Drug Utilization Review) warning
an alert or message generated by the pharmacy or insurance company computer system notifying the pharmacist of a potential drug safety or payment concern.
duration of action
the time drug concentration is above the minimum effective concentration (MEC).
edema
swelling from abnormal retention of fluid.
electrocardiogram (EKG or ECG)
a graph of the heart’s rhythms.
electrolytes substances
that in solution form ions that conduct an electrical current.
electronic medical record (EMR) or electronic health
record (EHR)
a computerized patient medical record.
elimination
the processes of metabolism and excretion.
embolism, embolus
a clot that has traveled in the blood-stream to a point where it obstructs flow.
emergency drug procurement
to quickly obtain a medication not currently in stock in the pharmacy in situations where the drug is urgently needed.
emulsifier
a stabilizing agent in emulsions.
emulsions
mixture of two liquids that do not mix with each other; one liquid is dispersed through the other by mixing and using an emulsifier for stability.
endocrine system
a system of organs and glands that secrete hormones into the bloodstream.
enteral
a route of administration to any organ in the alimentary tract (i.e., from the mouth to the anus).
enterohepatic cycling
the transfer of drugs and their metabolites from the liver to the bile in the gall bladder, then into the intestine, and then back into circulation.
enzyme
a complex protein that catalyzes chemical reactions.
enzyme induction
the increase in hepatic enzyme activity that results in greater metabolism of drugs.
enzyme inhibition
the decrease in hepatic enzyme activity that results in reduced metabolism of drugs.
epidural
a sterile, preservative-free medication administered into a patient’s epidural space (located near the spinal cord and backbone).
equivalent weight
a drug’s molecular weight divided by its valence; a measure of electrolyte concentration.
erythrocytes
red blood cells that transport oxygen and carbon dioxide.
estrogen, progesterone
female sex characteristics hormones produced by the female reproductive system and involved in calcium and phosphorus conservation.
ethics
a branch of philosophy that helps determine what
should be done in a principled sense.
Eustachian tube
the tube that connects the middle ear to the throat.
exempt narcotics
medications with habit-forming ingredients that can be dispensed by a pharmacist without a prescription to persons at least 18 years of age.
extemporaneous compounding
the on-demand preparation of a drug product according to a physician’s prescription, formula, or recipe, usually because the drug product is not available commercially.
extracellular fluid
the fluid outside the body’s individual cells found in plasma and tissue fluid.
fibrin
the fiber that serves as the structure for clot
formation.
fibrinogen
Factor I.
final filter
a device used to remove particulate matter; placed at the end point of an IV line just before it enters a patient’s vein.
finger cots
protective coverings for fingers.
first-pass metabolism
the substantial degradation of an orally administered drug caused by enzyme metabolism in the liver before the drug reaches systemic circulation.
flashball
a flexible rubber bulb near the needle adapter of an administration set used to determine if the needle is properly placed in the vein.
flexor movement
an expansion or outward movement caused by muscles.
flocculating agent
electrolytes used in the preparation of suspensions to form particles that can be easily redispersed.
floor stock
supplies, over-the-counter medications, and IV fluids available for immediate use on a nursing unit or ancillary area; these items are not labeled for individual patients.
flow rate
the rate (in mL/hour or mL/minute) at which solution is administered to the patient.
Food and Drug Administration (FDA)
a national regulatory body in the United States that oversees the approval, manufacture, and distribution of drugs for the safety of the public.
formulary
a list of stocked drugs that have been selected based on therapeutic factors as well as cost; a list of medications approved for use.
Formulation Record
formulas and procedures (i.e., recipes) for what should happen when a preparation is compounded.
fusion molding
a suppository preparation method in which the active ingredients are dispersed or dissolved in a melted suppository base.
gastric emptying
time the time a drug stays in the stomach before it is emptied into the small intestine.
gastrointestinal tract
part of the alimentary tract involved in the digestion of food and absorption of nutrients.
gauge
a measurement with needles: the higher the gauge, the smaller the lumen.
geometric dilution
a technique for mixing two powders of unequal quantity.
glaucoma
abnormally high pressure within the eye leading to optic nerve damage and loss of vision.
glomerular filtration
the blood filtering process of the nephron.
glucagon
a hormone that helps convert amino acids to glucose.
gout
a painful inflammatory condition in which excess uric acid accumulates in the joints.