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Physiology > Vitreous > Flashcards

Vitreous Flashcards

1
Q

Weight of vitreous? Volule

A

3.9g
3.9ml - may be greater in myopic eyes

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1
Q

What is the RI of vitreous

A

1.335

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2
Q

What cells produce collagen

A

fibroblasts

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3
Q

what makes up tropocollagen

A

three polypeptide chains
arranged in left handed helis

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4
Q

What are type I - III collagens?

A

Interstitial or fibrillar

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5
Q

What are Types IV - XI

A

amourphous material in interstiital rissue or BMs

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6
Q

How is collagen synthesised

A

DNA transcription
Processing of mRNA and translation of alpha chains in the ribosomes
At RER modification can occur
Triple helix is formed in RER that passes through Golgi

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7
Q

What gives collagen tensile strength?

A

Formation of cross links and lysine oxidation of collagen

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8
Q

What is the most common type of collagen in vitreous

A

Type II

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9
Q

What is the main glycosaminoglycan in vitreous?

A

Hyaluronan

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10
Q

What is glycoprotein contents of vit compared to aq

A

5x more in vit

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11
Q
A
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Physiology (15 decks)

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