vitamins and minerals in human metabolism

Question 1

which metabolic process is Niacin (vitamin B3) involved in?

Answer 1

Glycolysis

Question 2

Niacin = dietary precursors of what?

Answer 2

nicotinamide adenine dinucleotide

NAD+ and NADH

Question 3

what are these?

Answer 3

nicotinic acid and nicotinamide

Question 4

what is this

Answer 4

Nicotinamide adenine dinucleotide

Synthesis from Tryptophan possible

Question 5

what is the disease and symptoms associated with niacin B3 deficiency?

Answer 5

PELLAGRA

 4 D’s: Dermatitis, Diarrhea, and Dementia leading to Death

 Clinical manifestations: skin, gastrointestinal tract and the, nervous system

 Widespread cause of death until the early 20th century

 Niacin flour fortification has practically eradicated pellagra in developed countries

Question 6

where is niacin invloved in glycolosis as NADH?

Answer 6

glyceraldehyde 3-phosphate (GADP)

to

D-1,3-bisphosphoglycerate (1,3 BGP)

Question 7

what is meant by NAD + rection mechanism

Answer 7

Question 8

what happens to the NADH

Answer 8

The second half of glycolysis is known as the pay-off phase, characterised by a net gain of the energy-rich molecules ATP and NADH.[2] Since glucose leads to two triose sugars in the preparatory phase, each reaction in the pay-off phase occurs twice per glucose molecule. This yields 2 NADH molecules and 4 ATP molecules.

The NADH enter the mitochondria and enter the added to the electron transport chain and usedin the production of ATP.