Vitamins and Minerals Flashcards

1
Q

What is the function of Sodium (Na) as a macromineral?
Is it more concentrated in or out of the cell?

A

Sodium (Na) functions in the rising phase of action potential of nerve and skeletal muscle.
Its concentration is higher in the extracellular fluid.

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2
Q

What is the function of Potassium (K) as a macromineral?
Is it more concentrated in or out of the cell?

A

Potassium (K) functions in the falling phase of action potential of nerve and skeletal muscle.
Its concentration is higher in the intracellular fluid.

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3
Q

What is the function of Calcium (Ca) as a macromineral?
Is it more concentrated in or out of the cell?

A

Calcium (Ca) is necessary for muscle contraction, is a constituent of bone, and allows release of neurotransmitters at the presynaptic terminal.
Its concentration is higher in the extracellular fluid.

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4
Q

What is the function of Magnesium (Mg) as a macromineral?
Is it more concentrated in or out of the cell?

A

Magnesium (Mg) is located in the NMDA and AMPA receptor to modulate the entry of calcium and sodium into the post synaptic neuron. It’s also a cofactor for Kinases.
Its concentration is higher in the intracellular fluid.

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5
Q

What doses are needed for macrominerals?

A

Gram doses

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6
Q

What is the the function of Chromium (Cr) as a micromineral?

A

Chromium (Cr) is a Glucose Tolerance Factor that helps insulin bind to the cell.

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7
Q

What enzymes is Copper (Cu) a cofactor for?
Where are these enzymes found?

A

Copper (Cu) is a cofactor for Copper-Zinc Super Oxide Dismutase found in the cytoplasm, and for cytochrome c oxidase found in Complex IV in ETC.

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8
Q

What is the function of Fluoride (F) as a micromineral?
What else should you know about Fluoride (F)?

A

Fluoride (F) increases hardness of enamel of teeth.
You should know that high levels of Fluoride (F) are toxic.

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9
Q

What is Iodine (I) a cofactor for?
Describe what these chemicals are made of.

A

Iodine (I) is a part of Thyroxine T4, 2 tyrosine + 4 iodine, and part of Triiodothyronine, 2 tyrosine + 3 iodine.

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10
Q

Where is Iron (Fe) found?
What does Iron (Fe) deficiency lead to?

A

Iron (Fe) is found in cytochromes, hemoglobin, and myoglobin.
Iron (Fe) deficiency leads to microcytic anemia.

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11
Q

What enzymes is Manganese (Mn) a cofactor for?
Where are these enzymes found?

A

Manganese (Mn) is a cofactor for Mn Super Oxide Dismutase and Decarboxylase.
Both enzymes are found in the mitochondria.

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12
Q

What enzyme is Molybdenum (Mo) a cofactor for?
What does this enzyme do?

A

Molybdenum (Mo) is a cofactor for Xanthine Oxidase.
Xanthine Oxidase breaks down purines.

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13
Q

What enzyme is Selenium (Se) a cofactor for?
What else should you know about Selenium (Se)?

A

Selenium is a cofactor for Glutathione Peroxidase.
You should know that Selenium (Se) is deficient in soil today.

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14
Q

What enzymes is Zinc (Zn) a cofactor for?
What does Zinc (Zn) deficiency cause?

A

Zinc (Zn) is a cofactor for Cu-Zn SOD (located in the cytoplasm) and Carbonic Anhydrase (located in red blood cells).
Zinc (Zn) deficiency causes white lines on nails and poor wound healing.

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15
Q

What doses are needed for microminerals?

A

All microminerals are needed at microgram amounts. They are toxic at higher levels.

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16
Q

What is Vitamin B1 also known as?
What is its active form?

A

Vitamin B1 is also known as thiamine.
Its active form is Thiamine Pyrophosphate (TPP).

17
Q

What class of enzyme is Vitamin B1 a coenzyme for?
Other notes?

A

Vitamin B1 is a coenzyme for Decarboxylase.
B1 contains sulfur and is part of the Kreb’s cycle.

18
Q

What is Vitamin B2 also known as?
What is its active form?

A

Vitamin B2 is also known as riboflavin.
Its active form is FAD, FAD2, and FMN.

19
Q

What class of enzyme is Vitamin B2 a coenzyme for?
Other notes?

A

Vitamin B2 is a coenzyme for succinate dehydrogenase.
B2 is a part of the Kreb’s cycle.

20
Q

What is Vitamin B3 also known as?

A

Vitamin B3 is also known as Niacin (Niacinamide and Nicotinic acid).

21
Q

What are the active forms of Vitamin B3?
What class of enzymes are these active forms coenzymes for?
Other notes?

A

One active form of Vitamin B3 is NAD+–>NAD+H+ which is a coenzyme for dehydrogenase. This form of B3 is involved in the dehydrogenase in the Kreb’s cycle.
Another active form of B3 is NADPH+H+–>NADP+ which is a coenzyme for reductase. This form of B3 is involved in fat metabolism.

22
Q

What is Vitamin B5 also known as?
What is its active form?

A

Vitamin B5 is also known as Pantothenic acid.
Its active form is CoASH (Coenzyme A).

23
Q

What class of enzyme is Vitamin B5 a coenzyme for?
Other notes?

A

Vitamin B5 is a coenzyme for complexes that add CoASH.
B5 is involved in the Kreb’s cycle and other pathways.

24
Q

What is Vitamin B6 also known as?
What is its active form?

A

Vitamin B6 is also known as pyridoxine.
Its active form is pyridoxal 5 phosphate.

25
Q

What class of enzyme is Vitamin B6 a coenzyme for?

A

Vitamin B6 is a coenzyme for transaminases and amino acid metabolism.

26
Q

What macromineral and micromineral deficiencies are caused by birth control pills?

A

Birth control pills can cause deficiencies of the macromineral Magnesium and the micromineral Vitamin B6.

27
Q

What is Vitamin B9 also known as?
What is its active form?

A

Vitamin B9 is also known as folic acid.
Its active form is tetrahydrofolate (THF) (H4Folate).

28
Q

What class of enzyme is Vitamin B9 a coenzyme for?
Other notes?

A

Vitamin B9 is a coenzyme for methyl transfer reactions.
Note that B9 is involved in the methylation cycle.

29
Q

What is Vitamin B12 also known as?
What is its active form?

A

Vitamin B12 is also known as cobalamin.
Its active form is methyl cobalamin.

30
Q

What class of enzyme is Vitamin B12 a coenzyme for?
Other notes?

A

Vitamin B12 is a coenzyme for methyl transfer reactions.
Note that B12 is involved in the methylation cycle.

31
Q

What is Vitamin B7 also known as?
What is its active form?

A

Vitamin B7 is also known as biotin.
Its active form is carboxybiotin.

32
Q

What class of enzyme is Vitamin B7 a coenzyme for?
Other notes?

A

Vitamin B7 is a coenzyme for carboxylase.
B7 is made by good bacteria in the colon. Raw eggs contain a protein, avidin, which binds biotin and makes it unavailable.

33
Q

What is Vitamin C also known as?
What is its active form?

A

Vitamin C is also known as ascorbic acid.
Its active form is its reduced state.

34
Q

What class of enzyme is Vitamin C a coenzyme for?
What are some functions of Vitamin C?

A

Vitamin C is a coenzyme for hydroxylase.
Some functions of Vitamin C include carnitine synthesis, keeping iron and divalent cations in the +2 form for absorption, and recycling Vitamin E.

35
Q

How do you keep ascorbic acid in the reduced state?

A

Keep ascorbic acid in the reduced state with bioflavanoids like Quercitin, Rutin, and Rose Hips.

36
Q

What mammals cannot make Vitamin C from sugar?

A

Guinea pigs and primates are the only mammals that cannot make Vitamin C from sugar.

37
Q

Define microcytic anemia.

A

Red blood cells are smaller than normal.

38
Q

Define macrocytic anemia.

A

Red blood cells are larger than normal.

39
Q

What happens in the absence of folic acid (B9) and/or vitamin B12?
Other notes?

A

In the absence of folic acid and Vitamin B12, red blood cells are too large, but too few due to lack of mitosis. This results in macrocytic anemia.
Always give Vitamin B12 with folic acid.