Vitamins Flashcards
Fat-soluble vitamins
• They are absorbed by the intestinal mucosa as part of the
chylomicron complex.
• Deficiency in one or more of these vitamins can result from
chronic malabsorption.
• Deficiency in these vitamins develops slowly as stored
supplies are depleted.
- Vit A stores for more than 1 year
- Vit E stored for several months
- Vit K, D stored for only few days or weeks
Vitamins: General Information
• Diverse groups of nutrients that must be obtained from the
diet.
• They are low-molecular weight compounds that act mainly
as enzyme cofactors.
• Based on their solubility, vitamins are classified as:
(1) fat-soluble: vitamins A, E, K, and D.
(2) water-soluble: B vitamin group, vitamin C (ascorbic acid).
Vitamin A Function
Vision, growth, reproduction, immune responses,
Vitamin D Function
Bone calcification
Vitamin E Function
Antioxidant, neurological function, cardiovascular disease prevention
Vitamin K Function
Coagulation
Vitamin A Deficiency
Night blindness, growth retardation
Vitamin D Deficiency
Decreased calcium absorption, bone pain, osteoporosis, fractures
Rickets, Osteomalacia
Vitamin E Deficiency
Mild hemolytic anemia, ataxia, pigmentary retinopathy
Vitamin K Deficiency
Bleeding disorders, bruising deficiency
Water-soluble vitamins
• They are absorbed without the involvement of fat absorption.
• They function as coenzymes.
• All except vitamin C must be metabolically converted to
active forms.
• Storage:
- thiamine is stored for only few weeks
- vitamin B12 is stored for several years
- other B-complex vitamins and vitamin C are stored less than 3
months