Vitamins Flashcards

1
Q

Vitamin A

A
  • function: eyes, skin, immunity
  • toxicity: birth defects, liver injury, bone-related disorders
  • deficiency: night blindness, xerophthalmia (thickening and drying of conductive), keratomalacia (degeneration of cornea), blindness
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2
Q

Vitamin D

A
  • regulates calcium and phosphorus
  • deficiency causes rickets or osteomalacia
  • fortified foods meets dietary requirements
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3
Q

Vitamin E

A
  • antioxidant properties
  • dietary sources: fresh greens, seeds, oils
  • toxicity may increase risk for bleeding - particularly increases risk for hemorrhagic stroke
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4
Q

Vitamin K

A
  • action required for synthesis of prothrombin and other clotting factors
  • deficiency produces bleeding
  • adverse rxns: hypersensitivity rxn, hyperbilirubinemia in parenteral admin to newborns
  • TU: warfarin overdose, newborns
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5
Q

Fat Soluble Vitamins

A
  • A, D, E, K
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6
Q

Water Soluble Vitmains

A
  • C, B complex
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7
Q

Vitamin C

A
  • required for collagen production - wound healing, skin integrity
  • helps synthesis adrenal steroids
  • has antioxidant properties
  • facilitates iron absorption
  • deficiency can lead to scurvy - tooth loss, bleeding gums, poor wound healing
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8
Q

Niacin (Nicotinic Acid)

A
  • AE: large doses - vasodilation with flushing, dizziness, nausea
  • TU: can decrease cholesterol in large doses
  • deficiency: pellagra (scaling and cracking of the skin in areas exposed to the sun), GI disturbances, CNS
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9
Q

Thiamin (Vitamin B1)

A
  • coenzyme for carb metabolism
  • needs increase slightly during prego and breast feeding
  • deficiency: Beriberi, Wernicke-Korsakoff syndrome
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10
Q

Beriberi

A

Wet:
- fluid accumulation in the legs
- cardio complications (palpitations, ECG abnorms, high-output heart failure)
- treatment: recovery dramatic - good
Dry:
- neuro and motor deficits, no edema or cardio issues
- slow recovery

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11
Q

Wernicke-Korsakoff Syndrome

A
  • caused by alcoholism

- serious CNS disorder - nystagmus, diplopia, ataxia, inability to remember the recent past

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12
Q

Pyridoxine (Vitamin B6)

A
  • coenzyme in the metabolism of amino acids and protein
  • must first convert to its active form: pyridoxal phosphate
  • sources: fortified breakfast cereal, meat, fish, poultry, white potatoes, other starchy veggies and non-citrus fruits
  • deficiency sx: seborrheic dermatitis, microcytic anemia, peripheral neuritis, convulsions, depression, confusion
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13
Q

Vitamin B Complex

A
  • cyanocobalamin and folic acid
  • synthesis of DNA
  • deficiency: Both- megaloblastic, cyan. - neuro damage
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14
Q

***Harmful supplements to avoid

A
  • Comfrey, Kava, Ma Huang (ephedra)
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15
Q

Black Cohosh

A
  • treatment of menopause symptoms
  • not evaluated for long-term use
  • ADR: GI effects most common, rash, HA, weight gain, and cramps
    _ ***potentiate antihypertensive and the hypoglycemic effect of OHAs and insulin
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16
Q

Coenzyme Q-10 (CoQ-10)

A
  • antioxidant, important for ATP production
  • use: encephalomyopathies, CHF, myopathies due to statins use
  • ADR: well tolerated, some GI sx
  • DI: similar to Vit K and may antagonize effects of warfarin
17
Q

Echinacea

A
  • anti-viral, anti-inflammatory, immunostimulant effects
  • may interfere with immunosuppressants
  • use: prophylaxis of migraines
  • ADR: well tolerated, maybe mild GO complaints