Vitamins Flashcards
Vitamin
An organic compound essential for proper functioning of the body
*Vitamins must be obtained from dietary sources because..
human body can’t synthesize them in needed amounts Needed in micro and milligram quantities
– Enough vitamin can be obtained from balanced diet – Supplemental vitamins may be needed after illness
Many enzymes contain vitamins as part of their structures -
conjugated enzymes
Two classes of vitamins
Water Soluble and Fat Soluble
of known vitamins
13
*The water soluble vitamins
Vitamin C, Thiamin, Riboflavin, Niacin, Pantothenic Acid, Vitamin B6, Biotin, Vitamin B12, Folate
*Fat soluble vitamins
Vitamins : A, K, E, and D
*Water soluble vitamins (explain): absorption transport storage excretion toxicity dosage frequency relationship to coenzymes
absorption-directly into the blood
transport-travel without carriers
storage-circulate in the water filled parts of the body
excretion-kidneys remove excess in urine
toxicity-not likely to reach toxic levels when taken via supplements
dosage frequency-needed in frequent doses
relationship to coenzymes-function as coenzymes*
*Fat soluble vitamins (explain) absorption transport storage excretion toxicity dosage frequency relationship to coenzymes
absorption-first enter into the lymph system
transport-many require protein carriers
storage-found in the cells associated with fat
excretion-tend to remain in fat-storage sites
toxicity-likely to reach toxic levels when consumed from supplements
dosage frequency-needed in periodic doses
relationship to coenzymes- do not function as coenzymes
Vitamin C – Ascorbic Acid
Humans, monkeys, apes and guinea pigs need vitamin C
• Co-substrate in the formation of structural protein collagen
• Involved in metabolism of certain amino acids
• 100 mg/day saturates all body tissues - Excess vitamin is excreted
The preferred and alternative names for the B vitamins(8)
– Thiamin (vitamin B1)
– Riboflavin (vitamin B2)
– Niacin (nicotinic acid, nicotinamide, vitamin B3)
– Vitamin B6 (pyridoxine, pyridoxal, pyridoxamine) – Folate (folic acid)
– Vitamin B12 (cobalamin)
– Pantothenic acid (vitamin B5)
– Biotin
B vitamin functions
Serve as temporary carriers of atoms or functional groups in redox and group transfer reactions associated with metabolism
Vitamins A, D, E, K involved in..
plasma membrane processes
• More hydrocarbon like with fewer functional groups
• Vitamin A – Retinoid Derivatives
– Has role in vision - only 1/1000 of vitamin A is in retina
– 3 Forms of vitamin A are active in the body – Derived from beta-carotene
Functions of Vitamin A (4)
vision, Regulating Cell Differentiation, Maintenance of the healthy of epithelial tissues via epithelial tissue differentiation, Reproduction and Growth
Vitamin A (vision)
In the eye- vitamin A combines with opsin protein to form the visual pigment rhodopsin (GPCR) which further converts light energy into nerve impulses that are sent to the brain.