Vitamins Flashcards
Water Soluble Vitamins
B and C
Fat Soluble Vitamins
A, D, E, K
Thiamin (B)
-first to be discovered, sometimes called vitamin B1
-coenzyme needed for the breakdown of glucose …glucose is the energy source for nerve cells
-synthesizes neurotransmitters, ribose and deoxyribose=DNA sugars
- No UL
ex) found in the bran of brown rice and whole grains
abundant in pork, legumes, and seeds
Thiamin Deficiency Results in
Beriberi
Affects nervous and cardiovascular systems (rapid heartbeat and enlargement of heart)
Thiamin Deficiency in Alcoholics
Wernicke-Korsakoff syndrome
-due to decreased thiamin absorption due to alcohols effect on the GI tract
Riboflavin (B)
- visible indication of excess consumption with bright yellow urine (harmless)
- Forms 2 active coenzymes that serve as electron carriers
- function in reactions that produce ATP from carbs, fat, and protein
- involved in converting other vitamins such as (folate, niacin, vitamin b6, vitamin k) into their active forms
Best Source of Riboflavin
Milk
Riboflavin Deficiencies cause
Poor healing of injuries b/c new cells cannot grow to replace the damaged ones
(tissues most affected= eyes mouth tongue)
-occurs in conjunction with other B vitamin defiencies b/c riboflavin is needed to convert other vitamins into active form
Niacin (B)
- forms coenzymes essential for glucose metabolism
- synthesis of Fatty acids and cholestrol
- CAN BE SYNTHESIZED FROM ESSENTIAL AMINO ACID TRYPTOPHAN..only if enough is available to first meet the needs of protein synthesis
Niacin Deficiency
Pellagra ***3 Ds for symptoms: 1) Dermatitis 2) Diarrhea 3) Dementia if not treated, Death
- need for niacin is very widespread in metabolise so a deficiency causes major changes throughout the body
- used to be prevalent b/c local diet in south was mainly based on corn (low in tryptophan, niacin was not easily absorbed due to bounding of other molecules)
Good sources of Niacin
Meats and grains
RDA of niacin is expressed as
Niacin Equivalents (NEs) aka one NE=1 mg of niacin or 60 mg of tryptophan ..since trytophan can synthesize niacin..
Biotin (B)
- coenzyme that functions in energy metabolism and glucose synthesis
- Cooked eggs, liver, yogurt, and nuts
- Fruit and meat are poor sources
- Bacteria in GT tract synthesize biotin
- deficiency is uncommon but is observed in people with malabsorption and those taking certain medications for long periods
Pantothenic Acid (B)
Widely distributed in foods
- needed everywhere in the body
- part of coenzyme A (CoA) which is needed for the breakdown of carbs, FAs, and AAs.
- No UL
Vitamin B6
-needed to synthesize nonessential amino acids, make neurotransmitters, and synthesize hemoglobin, CONVERTS TRYPTOPHAN INTO NIACIN, breaks down glycogen into glucose into the blood
3 forms: pyridoxal, pyridoxine, and pyridoxamine
***these can be converted into the active coenzyme pyridoxal phosphate
ex) meat and fish, whole grains, and legumes