Vitamins

Question 1

What are the fat soluble vitamins

Answer 1

Vitamin A D E K

Question 2

Can ingestion of large amounts of fat soluble vitamin cause toxicity

Answer 2

Yes if stored for a prolonged time

Question 3

Which type of vitamins act as cofactors of enzymes in intermediary metabolism

Answer 3

Water soluble vitamins (B complex)

Question 4

What are the two types of vitamin A and which sources

Answer 4

V1- marine fish, fish oil, egg yolk , liver oii
V2- carotenoids, green plants , carrots spinach

Question 5

What are the physiological roles of vitamin A

Answer 5

Vision
Epithelial development
Immunity
Reproduction: it helps in development of spermatophore sis and foetal development

Question 6

Deficiency of vitamin A

Answer 6

-Xerosis (Dry eyes keratomalacia(softening of cornea )night blindness to total blindness
Dry and rough skin( hyperkeratinization)
Infertility due to lack of spermatogenesis, foetal malformations

Question 7

Therapeutic uses of vitamin A deficiency

Answer 7

-Prophylactic use In pregnancy and children 3000-5000 iu
-deficiency 50,000. - 100000 UI
-Skin diseases like acne, psoriasis

Question 8

Hypervitaminosis A symptoms

Answer 8

Nausea ,vomiting,
Bleeding, itching, dermatitis, chronic liver disease, exfoliation

Question 9

Vitamin E sources s

Answer 9

Wheat germs, cereals ,spinach and egg york

Question 10

Daily requirement of vitamin E is

Answer 10

10mg

Question 11

Physiological role of vitamin E

Answer 11

Acts as antioxidant Coenzyme

Question 12

Deficiency of vitamin E

Answer 12

Associated Neurological defects and neuromuscular diseases in children

Question 13

Therapeutic uses of vitamin E

Answer 13

G-6-pd prolonged treatment 100mg/day increases survival of rbcs

Question 14

Water soluble vitamins (B complex group)
Vitamin B1 ( thiamine) sources

Answer 14

Egg York , green vegetables, nuts and meat

Question 15

Physiological roles of vitamin B 1 ( thiamine

Answer 15

Coenzyme for Pentose phosphate pathway

Question 16

Deficiency of vitamin B1 (Thiamine

Answer 16

Syndrome of beriberi(dry and wet)
-Dry beriberi presents as neurological symptoms like numbness tingling paralysis of whole limb, memory loss
-wet beriberi; affects the cardiovascular system tachycardia, shortness of breath, ECG changes

Question 17

Therapeutic uses of Vitamin B 1

Answer 17

-Beriberi 100mg / day
-acute alcohol intoxication

Question 18

Vitamin B 2(Riboflavin) sources

Answer 18

Egg milk liver green leafy vegetables and grains

Question 19

Physiological functions of riboflavin vitamin B2

Answer 19

Coenzyme in oxidation -reduction reactions

Question 20

Deficiency of vitamin B2 riboflavin

Answer 20

Angular stomatitis, sore and raw tongue, ulcers in the mouth, anemia,

Question 21

niacin vitamin B3 related to tryptophan sources

Answer 21

Fish, cereal husk, nuts and pulses ‘
The amino acid tryptophan is mainly from animal protein and regarded as a provitamin

Question 22

Physiological role of vitamin B3 niacin and deficiency

Answer 22

Coenzyme and deficiency leads to pellagra( symptoms include dementia, diarrhea, dermatitis

Question 23

Therapeutic uses of niacin vit b3

Answer 23

-prophylactic use to prevent pellagra 20-50mg/day oral
-treatment of pellagra 200-500 mg/day
-Harry’s disease in which tryptophan is impaired and in carcinoid tumours

Question 24

Pyridoxine vitamin B6 sources and physiological roles

Answer 24

Coenzyme and sources include egg meat, soya beans and vegetables

Question 25

Vitamin c Ascorbic acid physiological roles

Answer 25

It’ has oxidative properties and collagen matrix integrity and in maintaining intercellular connective tissue

Question 26

Deficiency of vitamin c

Answer 26

Scurvy ( bleeding from gums , petechie, deformed teeth , anemia impaired wound healing and growth retardation

Question 27

Therapeutic use of vitamin c

Answer 27

Prevention of scurvy - orange juice, 50-100 mg/ day
Treatment r of scurvy 0.5-1.5g/day
Anemia ( vitamin c enhances iron absorption