Vitamins Flashcards
Who first coined the term vitamines and why?
Casimir Funk, he discovered beriberi (lack of B1 thiamine from eating white rice) ‘Life’ ‘nitrogen’ - not all have nitrogen but name stayed. Vitaminers are different forms of a vitamin, v similar in structure
How many vitamins are there?
13
What are the key functions of vitamins?
Support immune system Regulate gene expression Support neurological activity Facilitate ATP production Manufacture blood cells Regulate hormones
Where are vitamins absorbed?
Small intestine
Name a vitamin dependent enzyme and its function
CYP450 requires B vits for phase 1 liver detox
What are the fat soluble vitamins and where are absorbed?
ADEK absorbed from small intestine into lymphatic capillaries and into blood. Easily stored
What are the water soluble vitamins and where are they absorbed?
BC absorbed in small intestine directly into blood but can’t be stored (except B12) and easily excreted so need daily
Vit A: names, food sources, functions, deficiency, excess, bioavailability, toxicity
Beta-carotene (green leafy veg, orange veg and fruit)
Retinol (fish oils, liver, egg yolk)
Eye, skin, bone growth, antioxidant, immune health
Def: Night blindness, poor vision, dry eyes, rough skin
Beta-carotene broken down in walls of SI and converted to vit A in the liver. Bioavailability improved lightly steamed and eaten with fat.
Vit D: names, food sources, functions, deficiency, excess, bioavailability, toxicity
D2: Ergocalciferol (sun, sunflower seeds, mushrooms, chlorella
D3: Cholecalciferol (sun. liver, fatty fish, egg yolk)
Promotes absorption of Ca and P, bone health, immune system. A fat soluble steriod hormone.
Rickets, osteomalacia, tooth decay. brittle bones. Excess kidney stones.
Absorption enhanced with Mg. Both converted to calcidiol in the liver and circulates in the blood.
Vit E: names, food sources, functions, deficiency, excess, bioavailability, toxicity
d-alpha-tocopherol, dark leafy veg, veg and seed oils, legumes, almonds, nuts and seeds. Antioxidant, anti-aging, prevents heart disease, cancer, diabetes, protects cell membranes from oxidation.
Deficiency rare, dry hair, hair loss, reproductive disorders. Excess from supplements can hinder Vit A absorption. Works closely with Selenium and Vit c
Vit K: names, food sources, functions, deficiency, excess, bioavailability, toxicity
K1: Phylloquinone (green leafy veg, chlorella)
K2: Menaquinones (fermented foods, animal fats, meat, fish, eggs)
K1 - blood clotting
K2 - bone formation and bone health, cardio protective, cancer protective, blood sugar balance
Def rare - new borns early cord clamp, blood coagulation, nose bleeds, bruising, excessive menstrual bleed.
K2 synthesised by bacteria in LI
Vit B1: names, food sources, functions, deficiency, excess, bioavailability, toxicity
Thiamine - brewers yeats, pulses, beans, flaxseed, sunflower seeds, meat, fish, poultry, eggs
Energy production, helps cells convert carbs to energy, protein metabolism.
Def: impaired nervous function, low energy, beri beri
Vit B2: names, food sources, functions, deficiency, excess, bioavailability, toxicity
Riboflavin - wholegrains, nuts. seeds, green leafy, legumes, meat, fish, eggs
Energy production, carb, fat and protein metabolism.
Def: sores on lips and cracks, dermatitis, itchy sensitive eyes
Vit B3: names, food sources, functions, deficiency, excess, bioavailability, toxicity
Niacin - mushrooms, green leafy, nuts, seeds, tofu, pulses, beans, meat, eggs, fish
Energy production from digestion of fats, proteins and carbs, improves circulation, reduces cholesterol, regulates blood sugar.
Def: cognitive function, anorexia, anxiety, sores of skin, swollen tongue, poor memory, dementia
Vit B5: names, food sources, functions, deficiency, excess, bioavailability, toxicity
Pantothenic acid (pan - everywhere!) Almost all foods, avocados, tomatoes, lentils, pulses, meat, poultry, fish, eggs Nerve transmission, fat metabolism, immune system, stress response, formation of RBC, converting food into glucose, synthesises cholesterol. Def: rare, vomiting ab cramps, burning sensation in feet