Vitamins Flashcards

1
Q

Who first coined the term vitamines and why?

A

Casimir Funk, he discovered beriberi (lack of B1 thiamine from eating white rice) ‘Life’ ‘nitrogen’ - not all have nitrogen but name stayed. Vitaminers are different forms of a vitamin, v similar in structure

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2
Q

How many vitamins are there?

A

13

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3
Q

What are the key functions of vitamins?

A
Support immune system
Regulate gene expression
Support neurological activity
Facilitate ATP production
Manufacture blood cells
Regulate hormones
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4
Q

Where are vitamins absorbed?

A

Small intestine

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5
Q

Name a vitamin dependent enzyme and its function

A

CYP450 requires B vits for phase 1 liver detox

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6
Q

What are the fat soluble vitamins and where are absorbed?

A

ADEK absorbed from small intestine into lymphatic capillaries and into blood. Easily stored

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7
Q

What are the water soluble vitamins and where are they absorbed?

A

BC absorbed in small intestine directly into blood but can’t be stored (except B12) and easily excreted so need daily

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8
Q

Vit A: names, food sources, functions, deficiency, excess, bioavailability, toxicity

A

Beta-carotene (green leafy veg, orange veg and fruit)
Retinol (fish oils, liver, egg yolk)
Eye, skin, bone growth, antioxidant, immune health
Def: Night blindness, poor vision, dry eyes, rough skin
Beta-carotene broken down in walls of SI and converted to vit A in the liver. Bioavailability improved lightly steamed and eaten with fat.

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9
Q

Vit D: names, food sources, functions, deficiency, excess, bioavailability, toxicity

A

D2: Ergocalciferol (sun, sunflower seeds, mushrooms, chlorella
D3: Cholecalciferol (sun. liver, fatty fish, egg yolk)
Promotes absorption of Ca and P, bone health, immune system. A fat soluble steriod hormone.
Rickets, osteomalacia, tooth decay. brittle bones. Excess kidney stones.
Absorption enhanced with Mg. Both converted to calcidiol in the liver and circulates in the blood.

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10
Q

Vit E: names, food sources, functions, deficiency, excess, bioavailability, toxicity

A

d-alpha-tocopherol, dark leafy veg, veg and seed oils, legumes, almonds, nuts and seeds. Antioxidant, anti-aging, prevents heart disease, cancer, diabetes, protects cell membranes from oxidation.
Deficiency rare, dry hair, hair loss, reproductive disorders. Excess from supplements can hinder Vit A absorption. Works closely with Selenium and Vit c

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11
Q

Vit K: names, food sources, functions, deficiency, excess, bioavailability, toxicity

A

K1: Phylloquinone (green leafy veg, chlorella)
K2: Menaquinones (fermented foods, animal fats, meat, fish, eggs)
K1 - blood clotting
K2 - bone formation and bone health, cardio protective, cancer protective, blood sugar balance
Def rare - new borns early cord clamp, blood coagulation, nose bleeds, bruising, excessive menstrual bleed.
K2 synthesised by bacteria in LI

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12
Q

Vit B1: names, food sources, functions, deficiency, excess, bioavailability, toxicity

A

Thiamine - brewers yeats, pulses, beans, flaxseed, sunflower seeds, meat, fish, poultry, eggs
Energy production, helps cells convert carbs to energy, protein metabolism.
Def: impaired nervous function, low energy, beri beri

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13
Q

Vit B2: names, food sources, functions, deficiency, excess, bioavailability, toxicity

A

Riboflavin - wholegrains, nuts. seeds, green leafy, legumes, meat, fish, eggs
Energy production, carb, fat and protein metabolism.
Def: sores on lips and cracks, dermatitis, itchy sensitive eyes

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14
Q

Vit B3: names, food sources, functions, deficiency, excess, bioavailability, toxicity

A

Niacin - mushrooms, green leafy, nuts, seeds, tofu, pulses, beans, meat, eggs, fish
Energy production from digestion of fats, proteins and carbs, improves circulation, reduces cholesterol, regulates blood sugar.
Def: cognitive function, anorexia, anxiety, sores of skin, swollen tongue, poor memory, dementia

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15
Q

Vit B5: names, food sources, functions, deficiency, excess, bioavailability, toxicity

A
Pantothenic acid (pan - everywhere!) Almost all foods, avocados, tomatoes, lentils, pulses, meat, poultry, fish, eggs
Nerve transmission, fat metabolism, immune system, stress response, formation of RBC, converting food into glucose, synthesises cholesterol.
Def: rare, vomiting ab cramps, burning sensation in feet
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16
Q

Vit B6: names, food sources, functions, deficiency, excess, bioavailability, toxicity

A

Pyroxine - whoegrains, leafy greens, banana, carrots, potato, sunflower seeds, walnuts, avocado, pulses, beans, meat, fish, eggs
Protein digestion, nervous system function, blood cell and neurotransmitter formation
Acne, depression, irritability, insomnia, dysmenorrhoea

17
Q

Vit B7: names, food sources, functions, deficiency, excess, bioavailability, toxicity

A

Biotin - walnuts, almonds, peanuts, sweet potato, wholegrains, liver, egg yolk
Digest fats, carbs, proteins, energy production
Def: dermatitis, dry skin, alopecia, fatigue, red scaly rash around mouth, nose, eyes, brittle nails, seizures

18
Q

Vit B9: names, food sources, functions, deficiency, excess, bioavailability, toxicity

A

Folate - green leafy veg, oranges, lentils, beans, yeast, brown rice, beef liver, eggs
Embryonic development, DNA, protein digestion, formation of blood cells, memory.
MTHFR needed for methylation and reduce homocysteine levels. B2 needed to activate. Flour is fortified with folic acid. Pregnant women given supplements

19
Q

Vit B12: names, food sources, functions, deficiency, excess, bioavailability, toxicity

A

Methycobalamin, cyanocobalamin - not available in plant foods (VEGANS supplement!) chlorella, seaweed, but mainly meat, liver, kidney, seafood, eggs.
Def: dmage to nervous system, anorexia, fatigue, sore mouth and tongue, depression, mood swings. B12 needed for folate absorption. Intrinsic factor needed for absorption in ileum.
Metabolises fats and proteins, formation of RBC, brain and nervous system

20
Q

Vit C: names, food sources, functions, deficiency, excess, bioavailability, toxicity

A

Ascorbic acid, in all fresh raw fruit and veg. Antioxidant, collagen synthesis, makes thyroid hormones, forms adrenaline, cardio protective, immune system, converts cholesterol into bile acids.
Def: scurvy, frequent infections, poor wound healing, loss of appetite, muscle and joint pain, periodontal disease.
Increases iron absorption and is inhibited by alcohol. Cofactor for many enzymes

21
Q

Sodium, food sources, functions, deficiency, excess, bioavailability, toxicity

A

High: Sea salt, seaweed, rock salt. Low: celery, beetroot, chard, carrots
Controls water balance, nerve and muscle function, electrolyte balance
Too much: frequent urination, persistent thirst, headaches, salty food cravings.
Eat potassium rich foods to flush out excess sodium

22
Q

Potassium, food sources, functions, deficiency, excess, bioavailability, toxicity

A

Dark, leafy greens, avocados, watermelon, bananas, fruit, meat, poultry, fish
Water balance, insulin release
Def: Abdominal bloating, weak muscles, rapid heartbeat, cramps, constipation

23
Q

Chlorine, food sources, functions, deficiency, excess, bioavailability, toxicity

A

Component of table and sea salt, not in animal foods. Sea veg, olives, rye, celery, tomatoes
Fluid balance, hydrochloric acid (digestive enzyme) Key electrolyte in all bodily fluids, responsible for maintaining acid/alkaline balance
Def: low gastric acid

24
Q

Calcium: food sources, functions, deficiency, excess, bioavailability, toxicity

A

Dark leafy veg, kale, watercress, broccoli, almonds, sesame seeds, beans and peas, sardines, salmon.
Rickets, osteomalacia, osteoporosis, High BP, cramps, PMS
Vit D and K needed for calcium absorption into bones

25
Q

Magnesium (chlorophyll): food sources, functions, deficiency, excess, bioavailability, toxicity

A

Dark leafy greens, widely found in plants, legumes, wholegrains, meat, fish oil, egg yolk.
Regulates heart and muscle and nerve function, energy production, regulates blood pressure, electrolyte, sleep
Def: Low energy, insomnia, leg cramps, arhythmia

26
Q

Sulphur: food sources, functions, deficiency, excess, bioavailability, toxicity

A

Alliums, parmesan, soya beans, cabbage, garlic, Brussel sprouts, legumes, eggs, meat, fish
Liver detox - phase 2, antioxidant, insulin, ATP production
Part of thiamine and biotin, glossy hair and youthful complexion

27
Q

Iron: food sources, functions, deficiency, excess, bioavailability, toxicity

A

Fe3 - non haem (plant) Spinach, dark green leafy, figs, prunes, beetroot, quinoa, nuts and seeds, pulses, lentils, Fe2 - haem -red meat, oysters, sardines, chicken
Delivers oxygen to tissues, energy, haem more absorb than non haem, RBC formation, imunity, brain function
Def: Pallor, fatigue, irritability, dizziness.
Vit V increases absorption, phytic acid reduces absorption

28
Q

Zinc: food sources, functions, deficiency, excess, bioavailability, toxicity

A
Oysters, pumpkin seeds, nuts, chickpeas, amaranth, brazils, offal, fish, eggs.
Reproductive health (aphrodisiac) growth, breakdown alcohol, acne, wound healing, appetite, blood glucose regulation, T4 to T3. Needed with B6 to produce HCl.
29
Q

Selenium: food sources, functions, deficiency, excess, bioavailability, toxicity

A

Brazil nuts, garlic, mushrooms, wholewheat, corn, rye, liver, pork, poultry
Antioxidant, thyroid T4 to T3, sperm motility, required to produce glutathione

30
Q

Iodine: food sources, functions, deficiency, excess, bioavailability, toxicity

A

Think ‘SEA’ sea veg, ocean fish, eggs, dairy (low for vegans and veggies)
Thyroid (with selenium) T4 to T3, brain health, metabolism

31
Q

Copper: food sources, functions, deficiency, excess, bioavailability, toxicity

A

Sesame, cashew, quinoa, chickpeas, shiitake, avocado, liver, garlic, oysters, crab, prawn
Antioxidant, suppports skin, blood vessels and bone. Haemoglobin synthesis, myelin sheath (nervous system) vital to fight or flight

32
Q

Fluoride: food sources, functions, deficiency, excess, bioavailability, toxicity

A

Spinach, potatoes, grapes, black tea
mineralisation of bones and teeth
Def: tooth decay, osteopenia, osteoporosis

33
Q

Chromium: food sources, functions, deficiency, excess, bioavailability, toxicity

A

Broccoli, green beans, potatoes, barley, turkey, basil, garlic
Makes insulin receptor more effective - blood sugar regulation, diabetes, PCOS, lowers HbA1c
Vit c and B3 aid absorption