Vitamin B12 Flashcards

1
Q

Vitamin B12 common name is

A

Cobalamin

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2
Q

Cobalamin two functions are

A

remethylation of homocysteine and isomerization of methylmalonyl CoA to Succinyl CoA

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3
Q

Remthylation of homocysteine is needed to synthesis methionine, Remethylation of Hcy use

A

methyltetrahydrofolate in a reaction requiring methylcobalamin

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4
Q

isomerization of methylmalonyl requires

A

5’-deoxyadenosyl cobalamin

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5
Q

The nucleoside of cobalamin is

A

3’-deoxyadenosine

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6
Q

Deficiency of cobalamin will cause

A

anemia, spinal chord neuron degeneration, angular cheilosis, halitosis, gingivitis

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