Vitals Flashcards

1
Q

What are the adverse affects of Daptomycin, linezolid and imipenem

A

dapto myopathy linezolid low platelets and imipennem is sezures

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2
Q

Where is the erysipelas found

A

Face

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3
Q

Can ericipules cause rheumatic fever

A

No. It causes glomerulonephritis similar to pharyngitis but only pharyngitis causes emetic fever.

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4
Q

What are the three signs of disseminated gonorrhea

A

Joint inflammation rash and Tendonitis

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5
Q

Is acyclovir safe in pregnancyis💉🌡👶🏻

A

Yes. Give at 36 weeks and if there are lesions

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6
Q

What does WBC, leuk esterase and nitrates mean?

A

WBC and leuk esterase means bacteria is present. Nitrate means it’s gram negative

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7
Q

What mess can be used as acute and prophylaxis for malaria

A

Mefloquine

Atovaquone/proguanil

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8
Q

What is the initial therapy for angioedema?

A

Ecallantide which blocks bradykinin and kallikrein

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9
Q

What is the single most effective treatment for allergic rhinitis?

A

Intranasal steroids

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10
Q

What are the risk factors for ischemic heart disease?

A

DM, HTN, cigarette, HTL, PAD, obesity, inactivity, family history

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11
Q

Which meds are given before angioplasty.

A

Prasugrel, clopidogrel and ticagrelor

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12
Q

What do you do when there is contraindication to thrombolytics to lower mortality?

A

Angioplasty or PCI

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13
Q

What do you give if patient is allergic to aspirin or undergoes angioplasty and stenting or is having an acute MI?

A

Clopidogrel or ticagrelor

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14
Q

Why is prasugrel not used?

A

Because it increases bleeding for age >75 or wt <60kg

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15
Q

When is thrombolytics used?

A

ST elevation or LBBB w/in 12 hrs of CP

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16
Q

What lab abnormality will be caused by ACE and ARBs

A

Hyperkalemia

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17
Q

Which meds lower mortality in CHF?

A

Ace/arb, Beta blocker and spironolactone

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18
Q

When is biventricular pacemaker is the answer?

A

EF < 35 with QRS > 120

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19
Q

When is implantable cardioverter the answer?

A

Persisting EF of < 35

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20
Q

What is abnormal aortic gradient?

A

Anything greater than zero

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21
Q

When is S3 gallop pathological ?

A

When it’s older patient with CHF or mitral regurgitation.

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22
Q

How is Amyloid diagnosed on ekg and echo?

A

It shows low voltage ekg and echo will show speckled pattern

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23
Q

Symptoms of spinal stenosis?

A

Worse walking down hill or stairs

Relieved by walking uphill, sitting and cycling

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24
Q

What history is associated with arterial thrombosis?

A

AS and A Fib

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25
Q

What’s CHADS

A

CHF, HTN, age > 75, DM, CVA or TIA

Used for Afib life long anticoagulant

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26
Q

What’s the treatment for CHADS?

A

Score 0-1 needs aspirin
Score 2 or more needs warfarin
CVA/TIA equals 2

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27
Q

When do you give oxygen for a patient coming in with atrial arrhymia?

A

When a patient has COPD.

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28
Q

What do you give for torsade de pointes?

A

Magnesium

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29
Q

Which anti glycemic med is contraindicated in CHF?

A

Rosiglitazone

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30
Q

Which hyperglycemic meds increase insulin and block glucagon?

A

Gliptins

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31
Q

Which hyperglycemic meds promote slow gastric emptying and promote weight loss?

A

Exenatide and liraglutide

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32
Q

How does PTU work?

A

It blocks T4 to T3

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33
Q

What is the best initial test for Cushing’s syndrome?

A

24 hr urine cortisol

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34
Q

What do you do to figure out where is source of cushings?

A

Give high dose dexamethasone. If it lowers the ACTH then the origin is pituitary. If it does not suppress the ACTH then it’s ectopic. Scan chest for lung or carcinoid.

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35
Q

What is the treatment for addison disease?

A

Hydrocortisone which gives both gluco and minerocorticoids

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36
Q

When you have a patient with HTN + low renin and low Potassium think..

A

Hyperaldosteronism

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37
Q

Pheochromocytoma

A

Episodic hypertension and MEN 2

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38
Q

How do you tell patient is having severe asthma?

A

When no wheeze is heard

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39
Q

What test to order for SOB?

A

Oxygen, pulse ox, CXR and ABG

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40
Q

How to manage acute COPD

A

ABG. CPAP or bipap and then intubation

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41
Q

Pregnant lady with recent uti and lung fibrosis

A

Think nitrofuratoin

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42
Q

What does EKG show in ILD

A

Pulm HTN, right atrial and right ventricular hypertrophy

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43
Q

Risk factor for PPI

A

HCAP and c-diff

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44
Q

VAP

A

Fever, hypoxia, new infiltrate and increasing secretions

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45
Q

Treatment for positive PPD with no active infection.

A

Isoniazid for 9 months

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46
Q

What is characteristic of RA?

A

Anemia with normal MCV

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47
Q

What the difference between RA and alkylosing spondylitis?

A

Sacroiliac joins are spared in RA. Methotrexate is initial therapy.

Sacroiliac joints are involved. Methotrexate does not work. Give infliximab

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48
Q

Scleroderma

A

Tight skin + heartburn + Raynauds

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49
Q

How do you treat ILD?

A

Cyclophosphamide

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50
Q

Crest lung finding

A

Only pulmonary hypertension

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51
Q

Test for crest

A

Anti centromere antibody

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52
Q

What is the single most accurate test for PM/DM?

A

Biopsy

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53
Q

How do you differentiate between PM/DM and polymyalgia rheumatica?

A

PM/DM: weakness + CPK + Aldolase

Polymyalgia rheumatica : > 50 + proximal muscle pain (more than weakness) + ESR

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54
Q

Side effects of methotrexate

A

Lung and liver fibrosis

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55
Q

Wegners marker

A

C-Anca

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56
Q

Churg strauss

A

Vasculitis + eosinophilia + asthma

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57
Q

Takayasu

A

Young Asian female with diminished pulses

Don’t do biopsy
Do aortic arteriography or MRA

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58
Q

Treatment for acute gout

A

NSAID then steroid then colchicine

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59
Q

What are the risk factors for septic arthritis

A

Any arthritic joint or prosthetic joint

60
Q

Bone difference between paget and prostate

A

Paget is osteoclasts

Prostate is osteoblastic

61
Q

Lab for hgH

A

Microcytic anemia with high reticulocyte count

62
Q

Risk factor for metformin

A

B12 absorption

63
Q

Result of B12 replacement

A

Reticulocyte is first, neuron is last

64
Q

What is deleted with b12 therapy

A

Potassium

65
Q

How do you know that splenectomy will work for autoimmune hemolysis?

A

Response to IVIg means it will respond to splenectomy

66
Q

What test do you do for TTP/hUS

A

Adamts-13

67
Q

Treatment for paroxymal nocturnal hemoglobinuria

A

Eculizumab which inhibits C5 and prevents complement activation

68
Q

What is auer rods associated with

A

AML

69
Q

What is the risk factor for M3 acute polymyelocytic leukemia

A

DIC

70
Q

What happens to untreated CML?

A

It turns into ALL

71
Q

Jak 2 mutation is found in which diseases

A

PVera and ET

72
Q

What are elevated in PVera?

A

B12 and LAP

73
Q

What are the B symptoms?

A

Fever weight loss and night sweat

74
Q

What is eosinophilic esophagitis?

A

Dysphasia with history of allergies

Do scope and biopsy and treat with PPT and budesonide

75
Q

What is a common complain in GERD?

A

Cough

76
Q

What are the characteristics of peptic ulcer?

A

Single
<1 cm
Proximal near pylorus
Resolves with treatment

77
Q

Which acute hepatitis can be treated

A

Hep C

78
Q

Which hep c med does not need addition of interferon?

A

Sofosbuvir

79
Q

What are the meds for hep c treatment?

A

Boceprevir, telaprevir and simeprevir

80
Q

Which hepatitis does not have a vaccine or ppx ?

A

Hep c

81
Q

How do you determine portal HTN ?

A

If saag is > 1.1 then it’s portal due to cirrhosis or CHF

82
Q

What is the most common cause of death from hemochromatosis?

A

Cirrhosis

83
Q

What’s is the time limit for thrombolytics for stroke?

A

3 hrs

84
Q

What causes stroke in young people ?

A

Vasculitis or hypercoagulable state

85
Q

What is a common problem with anti epileptic drugs ?

A

Osteoporosis

86
Q

Why can’t we give anticholinergic drugs for PD to people under 60?

A

Benztropine and hydroxyzine cause memory loss

87
Q

Width cytotoxic drug causes PML?

A

Natalizumab

88
Q

What are the symptoms of pseudomotor ?

A
Headache
Sixth nerve palsy 
Visual field loss 
Transient obscure vision
Pulsutile tinnitus
89
Q

What is the single most important criterion for meningitis ?

A

CSF cell count. Thousands polys equals bacteria

90
Q

How do you classify encephalitis?

A

Fever + confusion

91
Q

What is the normal WBC count for CSF

A

1:500 RBC

92
Q

What is one of the causes of RLS?

A

Iron deficiency

93
Q

How do you figure out if it’s ATN is due to contrast?

A

It’s very rapid

94
Q

How do you know the Renal failure is not due to cyclophosphamide ?

A

Cyclophosphamide causes hemorrhage not renal failure

95
Q

What are the phosphate binder?

A

Calcium acetate

Calcium carbonate

96
Q

Treatment for extreme hyponatremia

A

Conivaptan and tolvaptan. They raise sodium by blocking ADH

97
Q

When do you use tamoxifen ?

A

When you have 2 or more first degree relatives with breast cancer

98
Q

What is the survival rate of testicular cancer?

A

90-95%

99
Q

Testing for cervical cancer

A

Ascus positive, do HPV test, if positive do colposcopy

100
Q

What is the best initial test for a patient coming with pain + crepitus + high fever + portal of entry ?

A

Surgery

101
Q

What is the standard for IV access for children without peripheral access ?

A

Interosseous proximal tibia for children less than 6. Give 20 ml/kg

102
Q

What is the standard for open skull fracture?

A

Tetanus toxoid and ppx antibiotics

103
Q

When do you give steroid for cerebral edema?

A

Tumors and abscesses. They don’t work for head trauma

104
Q

What is the classification of primary peritonitis ?

A

Spontaneous inflammation in children with nephrosis or adults with ascites with mild pain

105
Q

What is a GI medical emergency?

A

Cholangitis. ERCP is the treatment of choice

106
Q

What are the risk factors of pancreatitis ?

A
Alcohol 
Gallstones
Medications: didanosine, pentamidine, flagyl, tetracycline, thiazides, furosemide
Hyperglycemia
Trauma 
Post ERCP
107
Q

What are the signs of hemorrhagic pancreatitis?

A

Lower hmatocrit
Very high WBC > 18, glucose and bun
Very Low calcium

108
Q

What is reynold’s Pentad?

A

Jaundice fever abd pain Altered mental status and shock

109
Q

When do you worry about gas gangrene?

A

If it’s a penetrating or dirty wounds. Give large doses of IV penicillin and hyperbaric oxygen

110
Q

What are the blastic lesion ?

A

Prostate and breast

111
Q

What cause lyric lesions ?

A

Lung, renal, breast , thyroid and MM

112
Q

How do you differentiate plantar fasciitis?

A

Pain resolves quickly after walking

113
Q

What organisms are the most common in central line associated infections ?

A

A. Aureus, coagulase negative staph, candida

114
Q

What is the treatment for neonatal RDS?

A

Lucinactant

115
Q

What is VACTERL

A
Vertebral 
Anal
Cardiac
Teachea esophagus 
Radial renal
Limb
116
Q

What’s the differential diagnosis of double-bubble?

A

Duodenal atresia
Annular pancreas
Malrotation
Volvulus

117
Q

What is the risk of formula feed?

A

Necrotizing enterocolitis. Pneumatosis intestinalis is pathognomonic.

118
Q

What is the most feared complication of kernicterus?

A

Indirect bilirubin is the cause. Give immediate exchange transfusion

119
Q

What are test for suspected child abuse?

A

PT/PTT CBC
Skeletal survey
Head CT
Ophthalmic exam

120
Q

How do you differentiate epiglottis from croup?

A

Epiglottis does not have cough. Croup has barking cough

121
Q

What is the best prevention against bronchiolitis?

A

Breastfeeding

122
Q

What is the mutation in CF?

A

G551D. All CF patients should go through genotyping

123
Q

When is a murmur innocent?

A

Fever, infection and anxiety
When it’s systolic
Grade < 2

124
Q

Which infection causes chronic malabsorption?

A

Giardia. Get duodenal aspirate

125
Q

What are the risk for celiac disease?

A

Osteoporosis and T cell lymphoma

126
Q

When do you give rhogam?

A
At 28 weeks 
Within 72 hrs 
After miscarriage or abortion 
During amniocentesis 
With heavy vaginal bleed
127
Q

When is GBS related meningitis is not a vertices transmission?

A

When it’s after 1st week of birth

128
Q

What is the classic triad of congenital toxo?

A

Chorioretinitis
Intracranial calcification
Hydrocephalus

129
Q

What is the hep B vertical transmission rate?

A

80-90%

130
Q

What is the indication for methotrexate in pregnancy?

A

Pregnancy mass < 3.5 cm
Absence of fetal heart
BHCG < 6000
No history of folic supplement

131
Q

When is cerclage placed ?

A

At 14-16 wks

132
Q

How do you differentiate between leimyoma and adenomyosis?

A

Leiomyoma is asymmetric and non tenter

Adenomyosis is symmetric and tender

133
Q

What are the initial workup for ovarian mass?

A

B hcg
Ultrasound
Laparoscopy
Laparotomy if complex or greater than 7 cm

134
Q

What are the conditions where CA 125 is elevated

A
Ovarian cancer 
Cirrhosis 
Endometriosis 
Peritonitis
Pancreatitis
135
Q

What are the possible cause of amenorrhea?

A
PCOS
Hypothyroidism
Pituitary adenoma 
Elevated prolactin 
Meds like antidepressants and antipsychotic
136
Q

What is Denosumab?

A

It’s a RANKLe inhibitor that inhibits osteoclasts

137
Q

What are the contraindications to CT?

A

Creatinine > 1.5
MM
Metformin. Stop and restart are 48 hrs

138
Q

What are poor prognosis for a schizoprenia ?

A
Early age 
Negative symptoms
Poor premorbid function
Family history 
Disorganized or deficit type
139
Q

What’s the risk for clozapine ?

A

Agranulocytosis

140
Q

What’s the side effect of olanzapine ?

A

Weight gain

141
Q

How do you treat tardive dyskinesia?

A

Benztropine

142
Q

What are the adverse effects of lithium?

A

Einstein anomaly

Diabetes insipidus

143
Q

SSRI treats which disease?

A

Depression
GAD
Panic, OCD, social phobia,
Bulimia

144
Q

Passive aggressive personality disorder

A

Self aggression and self mutilation

145
Q

How do you identify an aspirin overdose?

A

Tinnitus

146
Q

What are the signs of methoglobinemia?

A

Cyanosis with normal pO2