Visual systems Flashcards
What are the different optical and functional anatomical components of the eye?
- Upper eyelid
- Lower eyelid
- Palpebral fissure
- Lateral canthus
- Medial canthus
- Caruncle
- Sclera
- Limbus (border between cornea and sclera)
- Iris
- Pupil
What different types of tears do we have?
Basal, reflex and emotional (crying)
What is the neurotransmitter of the lacrimal system?
Acetylcholine
Describe the process by which tears are produced in the lacrimal system
- Tears prodcued by the lacrimal gland
- Drain through the 2 puncta, openings on medial lid margin
- Flow through superior and inferior canaliculi
- Gather in tear sac
- Exit tear sac through tear duct into nasal cavity
What is the most superficial structure of the eye?
the “tear film”
What is the role of the tear film?
- Maintains smooth cornea-air surface
- Oxygen supply to cornea- normal cornea has no blood vessels
- Removal of debris (tear film and blinking)
- Bactericide
Describe the structure of the tear film
Composed of 3 layers:
- Superficial lipid layer: to reduce tear film evaporation - produced by a row of Meibomian Glands along the lid margins, v.thin- keeps the tear on the eye
- Aqueous (water) layer: tear film (tear gland) It delivers oxygen and nutrient to the surrounding tissue and it contains factors against potentially harmful bacteria- forms the main bulk of the tear film & thickest layer- acts as a lubricant
- Mucinous Layer corneal surface - maintains surface wetting- keeps film closely attached to eye
The mucin molecules act by binding water molecules,
to the hydrophobic corneal epithelial cell surface.
Which layer in the tear film protects the tear film from rapid evaporation?
Lipid Layer
What is the conjunctiva?
- Thin, transparent tissue that covers the outer surface of the eye
- It begins at the outer edge of the cornea, covers the visible part of the eye, and lines the inside of the eyelids
- It is nourished by tiny blood vessels that are nearly invisible to the naked eye
Where does the eye sit?
within the anatomical space known as the orbit.
What are the 3 layers that form the “coat” of the eye?
- The outer fibrous opaque layer called the Sclera (hard and opaque)
responsible for protecting the eye,
and maintaining the shape of the eye. - The middle pigmented vascular layer called the Choroid,
responsible for providing circulation to the eye,
and shielding out unwanted scattered light. - The innermost Neurosensory Layer called the Retina,
responsible for converting light into neurological impulses,
to be transmitted to the brain via the Optic Nerve.
What is the role of the sclera/ it’s features?
“the tough, opaque tissue that serves as the eye’s protective outer coat. “
- High water content
What is the cornea?
The transparent, dome-shaped window covering the front of the eye
- Attached to sclera
What are the features/ what is the role of the Cornea?
role= Powerful refracting surface, providing 2/3 of the eye’s focusing power. Like the crystal on a watch, it gives us a clear window to look through (look inside the eye for disease)
- 5 layered
- Has no blood supply; endothelium absorbs O2 directly
- Low water content
What are the 5 layers of the cornea?
1 – Epithelium (most superficial)
2 – Bowman’s membrane
3 – Stroma – its regularity contributes towards transparency (made of collagen)
4- Descemet’s membrane
5- Endothelium – pumps fluid out of corneal and prevents corneal oedema- low water content: allows passage of glucose to nourish cornea
What is the uvea?
Vascular coat of eyeball and lies between the sclera and retina.
Describe the structure of the uvea & why is this clinically significant ?
Composed of three parts – iris, ciliary body and choroid.
Intimately connected and a disease of one part also affects the other portions though not necessarily to the same degree.
What is the choroid? Where is it located?
Choroid - lies between the retina and sclera.
It is composed of layers of blood vessels that nourish the back of the eye.
What is the Iris & what is it’s role?
“Round opening in the centre is the pupil.”
- Embedded with tiny muscles that dilate (widen) and constrict (narrow) the pupil size
- Controls light levels inside the eye similar to the aperture on a camera.
Describe the structure of the lens?
(lies behind the iris)
Outer acellular capsule
Regular inner elongated cell fibres – transparency
May loose transparency with age – cataract (lens becomes opaque)
What is the function of the lens?
responsible for one third of the refractive power of the eye.
Transparency
Regular structure
Refractive Power
1/3 of the eye focusing power - higher refractive index than aqueous fluid and vitreous
Accommodation
Elasticity
What is the Retina?
Very thin layer of tissue that lines the inner part of the eye.
What is the function of the Retina?
- Responsible for capturing the light rays that enter the eye. Much like the film’s role in photography.
- These light impulses are then sent to the brain for processing, via the optic nerve.
What is the role of the optic nerve?
- connects to the back of the eye near the macula
- transmits electrical impulses from the retina to the brain
- visible portion is called the optic disc
What is the “blind spot”
Where the optic nerve meets the retina there are no light sensitive cells. It is a blind spot
What is the Macula?
- A small and highly sensitive part of the retina responsible for detailed central vision
- Located roughly in the centre of the retina, temporal to the optic nerve
- The fovea is the very centre of the macula. The macula allows us to appreciate detail and perform tasks that require central vision such reading.
What is the fovea?
The most sensitive part of the retina
- It has the highest concentration of cones (fine vision), but a low concentration of rods (more sensitive to light)
- This is why stars out of the corner of your eye are brighter than when you look at them directly.
- But only your fovea has the concentration of cones to perceive in detail
What are the 2 types of vision?
Central and peripheral vision
What is “central”/ foveal/ Macular vision?
Responsible for detailed, central vision and daytime colour vision – fovea has the highest concentration of cone photoreceptors
Reading, facial recognition
How is central/ foveal vision tested?
Assessed by visual acuity assessment
What does a loss of foveal vision cause?
Loss of foveal vision – Poor visual acuity
Patients with loss of central vision will have problems with reading, and recognizing faces.
What is peripheral vision?
Peripheral Vision specializes in detecting shape, movement in the environment and night Vision
Navigation vision
How is peripheral vision assessed?
Assessed by visual field assessment
What does a loss in peripheral vision cause?
Extensive loss of visual field – unable to navigate in environment, patient may need white stick even with perfect visual acuity
Patients with extensive loss in peripheral vision will have problems navigating the world.
Describe the structure of the retina
- The retina forms the innermost layer of the coat of eye in the posterior segment.
- The retinal pigment epithelium transports nutrient from the choroid to the photo-receptor cells,
and removes metabolic waste from the retina.
Outer layer:
Photoreceptors (1st order neuron)
Detection of Light
Middle layer:
Bipolar Cells (2nd order neuron)
Local signal processing to improve contrast sensitivity, regulate sensitivity
Inner layer:
Retinal ganglion cells (3rd order neuron)
Transmission of signal from the eye to the brain
What are the 2 main classes of photoreceptors?
Rods and Cones
Compare rods with cones
RODS:
Longer outer segment with more photo-sensitive pigment
100 times more sensitive to light than cones
Slow response to light
Responsible for night vision (Scotopic Vision)
120 million rods
CONES:
Less sensitive to light, but faster response
Responsible for day light fine vision and colour vision (Photopic Vision)
6 million cones
Describe the distribution of the photoreceptors
RODS:
- Rod photo-receptors are responsible for night vision,
known as Scotopic Vision.
- Rod photo-receptors are widely distributed all over the retina, with the highest density just outside the macula.
- The density of rod photo-ceptors gently tails off towards the periphery.
NOTE that rod photo-receptors are completely absent within the macula.
CONES:
- Cone photo-receptors are responsible for day vision,
or Photopic Vision.
- Cone photo-receptors are distributed only within the macula.
Where can one find the highest concentration of Rod photoreceptors in the retina?
A) Optic Disc
B) Fovea
C) 10-20 degrees away from fovea
D) 20-40 degrees away from fovea
D) 20-40 degrees away from fovea
the eye captures different colours through different photoreceptors, true or false?
TRUE
What colours do each photoreceptor capture?
In humans, there are three cone photo-pigment sub-types:
the S-Cones with photo-pigment sensitive to short wavelength – colour blue,
the M-Cones with photo-pigment sensitive to medium wavelength – colour green,
and the L-Cones with photo-pigment sensitive to long wavelength – colour red.
This forms the basis of colour vision.
Rods are used for night vision and spatial recognition and are not really sensitive to any particular colour
How do we see other colours than red, blue and green, like yellow? what photoreceptors are stimulated?
Yellow light has a wavelength between the peak sensitivity wavelengths of M-Cones and L-Cones.
Yellow light stimulates both M-cones and L-cones equally.
Biologically, we experience yellow light as a combination of green and red light.
What is the commonest form of colour vision deficiency?
- Deuteranomaly also known as Daltonism is the most frequent form of colour blindness.
- People with deuteranomaly are not completely colour blind but they don’t perceive the colour red.
It is caused by the shifting of the M-cone sensitivity peak towards that of the L-cone curve,
causing red-green confusion. This is called Anomalous Trichromatism. Deuteranomaly is the commonest form of Anomalous Trichromatism.
What condition causes full colour blindness?
achromatopsia
Colour Vision deficits can also be caused by the absence of one or more of the 3 cone photo-pigments.
What are the different types of deficits?
- In Dichromatism, only two cone photo-pigment sub-types are present.
- In Monochromatism, there is complete absence of colour vision.
* This can be caused by Blue Cone Monochromatism,
with the presence of only blue L-cones.
* Or by Rod Monochromatism,
in which there is a total absence of all cone photo-receptors.
* Patients with Blue Cone Monochromatism have normal day light visual acuity,
* whereas Patients with Rod Monochromatism have no functional day vision.
What is meant by the term “refraction”
- When light is passing through one medium into another
- The velocity changes
What is the “indec of refraction”- what does it tell us?
Index of refraction (n)= speed of light in a vacuum/ speed of light in a medium
- n tells us how much the light changes speed
- All substances have an index of refraction and can be used to identify the material.
What are the “Refraction Facts”?
- As light goes from one medium to another, the velocity CHANGES
- As light goes from one medium to another, the path changes (light bends)
What exactly is light doing when it reaches a new medium?
Some of the light reflects off the boundary and some of the light refracts through the boundary.
Angle of incidence = Angle of Reflection, true or false?
TRUE
Angle of Incidence > or < the Angle of refraction depending on the direction of the light, true or false?
TRUE
What are the 2 basic types of lens?
Convex and Concave