Visual System Flashcards

1
Q

How does physiological coding of sensory experience work?

A

stronger stimulus evokes more action potentials, and as you push MORE, the number goes up linearly, stronger stimulus is perceived as stronger

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2
Q

How do low level processes get converted into complex processes? What are some examples?

A

Low level:

  • orientation
  • colour
  • contrast
  • disparity
  • movement

Complex:

  • contour integration
  • surface properties
  • shape discrimination
  • surface depth
  • surface segmentation
  • object motion/shape from cues
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3
Q

What is the wavelength of light our eyes can detect?

A

400-750 nm roughly (purple-red)

Heat emits a longer wavelength of light that we can’t see but some animals can!

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4
Q

What are the various parts of your eye? What detects light in the retina?

A

Retina: detector like in a camera
Photoreceptors are scattered across the whole thing to detect light.
Lens: focuses light onto fovea
Bipolar and ganglion cells: bring information to the optic nerve, must be moved (pushed to the side) in order to access photoreceptors at the fovea

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5
Q

What is a receptive feild? Tell me about them.

A

Region of space (somatosensory, tonal, visual, chemical) that elicits change in firing

  • packed tighter in the fovea
  • periphery cells are more sparce
  • circular patches are feilds OF a particular ganglion cell: light hits one of the photoreceptors and the info converges onto the ganglion cell

-receptive fields are smaller in the fovea

A photon of light, anywhere it hits activates the same ganglion cell in that receptive field

Same as for skin!

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6
Q

what are the degrees for receptive fields in periphery vs. fovea?

A

periphery: 10 degrees
fovea: 0.1 degrees

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7
Q

What are the two major classes of photoreceptors?

A

RODS AND CONES
Cones: fovea primarily, higher resolution, requires more light
Rods: periphery, rod based vision is lower resolution but better night vision.

Higher convergence of photoreceptors in Rods (more rods per ganglion cell, allows for smaller stimulus to help spatially sum and reach threshold)

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8
Q

What is the distribution of rods/cones in the eye?

A

6 million cones
100 million rods

ALl bundle togetehr and go through the optic nerve through optic disk

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9
Q

What is your blind spot?

A

the optic disk/where the optic nerve bundles together and goes out !!
When you have both eyes open this blind spot is covered for

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10
Q

Support the statement “different cones are sensitive to different wavelengths”

A

S cones, M cones, L cones etc. All have different pigments that absorb different wavelengths of light
Simultaneous activity in these cones is what colour vision is!
POPULATION CODING
- if you only had one cone type you couldn’t differentiate colours, but when you have them at the same time, the cone will be able to tell because it will absorb more of one wavelength and less of another!
Absorbing this light promotes changes in NTs and neurological activity

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11
Q

How does night vision work?

A

exclusively rod based, therefor colour is not perceived, it is all grey
maximally sensitive to light around 500 nm

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12
Q

What are on-center receptive fields and how do they work?

A

Region of the receptive field that is sensitive/non sensitive to light.
If you fire on the “on” area, you will see action potentials
If you fire on the off area, there will be no potentials, but as soon as you REMOVE the stimulus from the ‘off’ section, APs will fire because of RELATIVITY: removal of the light is like administering darkness
If you cover the whole thing with light: nothing happens becuase you need to see contrast. a lot of light/lot of darkness is essentially the same
If you cover half of both areas, you will get unsteady firing, a bit of imbalance

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13
Q

What is contrast enhancement and how does it work?

A

When viewing colours next to each other that are slightly different, there is a phenomenon known as “mach bands” and they are spots where light is a little more bright/dark on either side of the contrast. This is due to LATERAL INHIBITION
-sharpens attention and makes it more clear

The intensity is the same for most of the colour (same level of inhibiton from neighbouring neurons) HOWEVER when next to another colour, the inhibition is higher/lower than usual so it exaggerates that receptor’s response to the light because it is more/less inhibited

This was initially measured in crabs

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14
Q

Ask becca about that slide in visual systems that is highlighed “

A

contrast enhancement via. lateral inhibiton

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15
Q

What is the difference between on center and off center receptive fields when a dark object appears? why is this important?

A

on center: when a dark object appears, APs fire at a lower frequency than baseline: the brain will realize that there is a signal MISSING from baseline firing but takes about 100 ms to detect (reflexes)
off center: when a dark object appears it fires at a higher frequency, this allows you to detect change faster!

Beneficial: you can detect changes in contrast quickly, more activity isn’t always ‘better’ the brain cares about changes in activity
you want to know if there is change happening in front of you ASAP

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16
Q

What does the optic nerve convey?

A

20 different representations of the world that differ in polaritiy (on/off), spatial resolution, temporal responsiveness (sustained or transient), spectral filtering (colour) and selectivity for things like motion

17
Q

What is the Retinal Thalamic Visual cortex pathway?

A

The left visual field is projected onto the right side of the retina, processed in right thalamus and primary visual cortex and vise versa

Info from 2 eyes are kept separate within thalamus and V1, forming OCULAR DOMINANCE COLUMNS
-alternating pattern of left and right visual fields alternating from left and right eye are orgnized systematically

Adjacent areas of visual field are detected by adjacent areaes in visual field. This RETINOTOPIC MAP is preserved in thalamus and visual cortex

Optic nerve goes to lateral geniculate nucleus which goes to V1

Pixels in the retina have the same relationship in the cortex!

18
Q

How many layers is the neocortex divided into? What is some important info you should know about them?

A

6
Folded elaborate structures in our brains
Cells are packed densly/sparesly based on what area it is and where it is - some layers may be thicker in other areas

LAYER 5: motor cortex is very large
LAYER 4: receives input from the thalamus, very big layer in the visual cortex, important for sensory input

19
Q

where do inputs from the thalamus go?

A

layer 4

20
Q

How is the neocortex arranged?

A

Organized in columns, the layers are connected and send axons to different areas within columns and some stretch out
Collection of cells in the different layers connect them
In most columns, neurons process the same type of info/stimuli

21
Q

What is the circuit basis of orientation? the experiment and findings?

A

An electrophysiological experiment on a cat demonstrated that in select cells (later called simple cells) in V1, there would be more firing when the light was shone in the correct orientation!
- they only got consistent responses this way!

22
Q

How do on/off receptive fields create the orientation circuit?
***

A

The receptive fields relay information from layer 4 to layer 3.
Each layer 4 neurons represents a point of light in the visual field (remember retinotopic map), they converve into layer 3 to create a “bar” of light receptive field
this is an example of electrophysiological summation (each layer 4 neuron needs to activate to reach threshold in layer 3
BUILD A MEANINGFUL IMAGE instead of just strips
***

23
Q

What are the field properties of columns in V1?

A
  1. Visuotopic: adjacent stimuli stay relative to each other the whole way. A striped stimulus will appear that way in the retina, thalamus and V1
  2. Ocular Dominance: preferential response to info from one eye or the other, ONLY in V1 (not v2)
  3. Orientation specific: need to have cells that care about orientation
  4. Blobs: colour cells, neurons hat respond to different colours, not in all the columns, intersperced. View with staining as apposed to functional imaging*
24
Q

What is a hypercolum?

A

contains full range of orientation selective columns, ocular dominance, blobs, visuoretinotopic maps!
For every portion of the visual feild, there is a hypercolumn that responds to it!

25
Q

How do we know that information from the visual field is linked together in different brain regions?

A

Stains show:
axons extending laterally with branches/clustering of axonal branches
Overlap of GFP axonal branches that have similar orientation selectivity suggesting linking of similar info

In vivo: image activity of neurons around one of interest, sends info to nearby columns that represent same orientation
-this can link cells into a population (which is needed to detect colour etc)

26
Q

what is the difference between simple cell and visual field linking?

A

simple cell: cells congregated onto a single cell that sums inputs to make something complex

visual processing: something complex happens due to simultaneous activation and activity of neurons