Visual System Flashcards
The fact or phenomenon of light being deflected in passing obliquely through the interface between one medium and another through a medium of varying density
Refraction
First site of refraction as light enters eye; is this refraction variable?
Cornea; not variable (accounts for 2/3 of light bending)
The second site of refraction in the eye is the ___ which adds a variable amount of bending. Variability depends on curvature, which is under physiological control. The ______ the structure above, the more refraction there is; the ______ the structure, the less refraction
Lens; rounder; flatter
Increasing curvature of the lens = ciliary muscle ______, which alows suspensory ligaments to ______. The lens assumes a more _____ shape; this is used for ______ vision
Contracts; loosen; rounded; near
Decreasing curvature of the lens = ciliary muscle ______, causing suspensory ligaments to _______, thus causing the lens to _____; used for ____ vision
Relaxes; tighten; flatten; far
Condition in which lens becomes stiffer in aging, loss of elasticity
Presbyopia
The near response of the eyes requires what 3 events?
Contraction of ciliary muscles
Convergence of eyes
Constriction of pupil
Path of light from entry to eye to activation of photoreceptor
Ganglion cells Amacrine cells Muller glia Bipolar cells Horizontal cells Rods/cones
What are the 3 vertically oriented cell-types in the retina?
Receptor cells (rods/cones) Bipolar cells Ganglion cells (subtype melanopsin ganglion cells)
Which type of photoreceptor is associated with convergence, dim light, and sensitivity but NOT acuity?
Rods
[cones have less convergence, but maximized acuity]
Rod/cones constantly release NT ________; this release is at its highest in the _____, and lowest when there is _______ (hyperpolarization of cells)
Glutamate; dark; light
In differentiating ON-centers from OFF-centers:
Activation of a photoreceptor in the center of an ON-center bipolar cell’s receptive field causes ______
Activation of the periphery of this bipolar cell’s receptive field causes ________
The opposite is true for OFF-center cells
Depolarization
Hyperpolarization
[so for OFF-center cells, activation of a photoreceptor in the center causes hyperpolarization while activation in the periphery causes depolarization]
________ bipolar cells increase their discharge rate to luminance increments in the receptive field center
______ bipolar cells increase their discharge rates to luminance decrements in the receptive field center
ON-center
OFF-center
The glutamate receptor in depolarizing bipolars is a GPCR that _____ cGMP-gated ion channels similar to light transduction in photoreceptors.
Channels _____ when less glutamate is present
Closes
Open
Describe activity of an ON-center bipolar cell by a cone photoreceptor in the dark
- Glutamate would activate a Gi GPCR-metabotropic receptor on the ON-center cell
- Results in a decrease in cation influx into bipolar cell
- Cell is hyperpolarized