visual part 3+4 Flashcards

1
Q

Describe the neural sequence from retina to primary visual cortex

A

Right and left visual fields project to opposite lateral geniculate body and primary visual
cortex
Partial decussation of ganglion cell axons in the optic chiasm

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2
Q

What is partial decussation?

A

(crossing) of fibres from the temporal visual fields (the nasal hemi-retina) of both eyes

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3
Q

What is the difference between homonymous and heteronymous hemianopsia?

A

Hemianopsia: loss of half visual field
Heteronymous: loss of opposite visual fields due to lesion of
central optic chiasm (pituitary tumors)
Homonymous: loss of same visual fields due to lesion of
optic system between optic chiasm and visual cortex

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4
Q

Describe the differences between ON and OFF retinal cells

A

Light stimulates rod and cone receptors which activate ON and OFF bipolar & ganglion cells
ON bipolar cells have glutamate receptors that respond to decreased glutamate with depolarization and excitation of the ganglion cell, activated in the presence of light in center of the RF–> OFF cells are inhibited
OFF: With darkness in center of the RF, photoreceptors release more glutamate
OFF bipolar cells have glutamate receptors that respond to increased glutamate with depolarization that excites the OFF ganglion cell

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5
Q

What are center-surround receptive fields in the retin

A

Circular areas of retina are organized into concentric rings
where inner receptors activate ganglion cells one way, the
surrounding region activates it in the opposite way.
On-center retinal ganglion cells respond–>light spots
surrounded by dark backgrounds
Off-center ganglion cells–>dark spots, light backgrounds

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6
Q

how do center-surround receptive fields affect perception of visual boundaries?

A

Center-surround fields enable ganglion cells to encode contrast. emphasize EDGES
Rate of activity of ganglion cells indicates amount of contrast between and center part of its
receptive field.
SOOOO
Because ganglion cells enhance contrast, a moderately bright region may appear brighter or darker depending on the background.

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7
Q

What is the difference between the parvocellular and magnocellular pathways from retina to LGN and visual cortex?

A

different types of ganglion cells–>parallel processing conveys different types of visual information along each route
Parvocellular (midget): color and shape information for object perception and identification.
90% of axons in optic nerve,receive input from 1 or a few
photoreceptor (esp cones in fovea),high acuity with smaller center-surround receptive fields
Magnocellular (parasol) : movement for perception of motion and direction to enable visual attention, alerting,
grasping.
5% of axons in optic nerve, receive input from larger group of photoreceptors (esp rods in periphery) ,low acuity with large center-surround receptive fields
dark or night vision

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8
Q

ventral and dorsal streams cortical and processing of visual information

A

ventral=parvocellular stream: information from the
fovea (cones), acuity and color, through association
cortices including the inferotemporal gyrus. high levels
of visual perception and cognition, ‘What’ (not where).

dorsal=magnocellular stream:peripheral retina (rods) into
posterior parietal cortex. This computes vision for ‘action’ ‘How’ and ‘Where’.

streams converge into prefrontal cortex to form working
memory

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9
Q

Give a brief description of simple and complex cells in the primary cortex.

A

Primary visual cortex develops perception of form, color,direction of movement and binocular vision through activity of simple and complex cells organized in columns

Simple:input from several geniculate cells that individually respond to contiguous points along the bar of light w/ specific orientation
Complex:respond to a properly oriented EDGE or bar of light, but anywhere within the receptive field. take info from SIMPLE cells

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10
Q

What characterizes visual cortical columns?

A

vertical zones of cortex that use combinations of simple

and complex cells to sort information into various properties.

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11
Q

What impact does cortical feedback have on incoming visual input?

A

Cortical columns generate complex activity that is
used to provide feedback onto sensory pathways. –> focus on particular aspects of the environment

Cortical feedback to lateral geniculate nucleus ->sensory input according to the ongoing behavior of the organism
Enhances the acuity of their responses to bars of light by
altering lateral-inhibition-like mechanisms among LGN neurons

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12
Q

What impact does neuromodulation by the reticular formation have on incoming visual information?

A

LGN cells are modulated by brainstem pathways using norepinephrine, serotonin (5HT), ACh, NO (reticular formation).
Cortical cells that respond optimally to a particular RF (orientation, movement, ) will sharpen the responses of any LGN cell that responds to those particular features–> amplification

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13
Q

What are the visual association cortices?

A

V1: projects different aspects of visual cognition into dorsal and ventral streams of association cortices, integrating the information
V2 cells are tuned to complex properties: angles between lines, orientation of illusory contours and whether the stimulus is part of the figure or the ground
V4:tuned to color and more complex shape complex outline-shapes
Inferotemporal cortex: scale and position, objects such as faces
MT (middle temporal) is part of the dorsal stream
for detecting complex, global motion

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14
Q

How do the inferotemporal and fusiform cortices differ from the other visual association cortices?

A

inferotemporal responds to both halves of visual field, information transmitted by interhemispheric axons via the corpus callosum, EMOTION. focus on something
and you notice it more, short and long term memory
Fusiform: Face recognition, esp. with emotional valence (connection with amygdala) . Synesthesia

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15
Q

Describe visual neglect and its impact on perception of one’s visual field.

A

Loss of function in the right visual association cortices

left side of picture missing

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16
Q

What does Wernicke’s area do?

A

part of cerebral cortex linked to speech. understanding of written and spoken language

17
Q

. Describe the visual pathways mediated by the superior colliculus (SC).

A

Input from :
Retinal koniocellular ganglion cells: moderate spatial
resolution, large receptive fields, no center-surround fields
Visual, auditory, association, and motor areas of cerebral
cortex
Projects visual information to
– cortical areas for eye movements including saccades
– brain stem and spinal cord areas for head turning
SC in turn modulates CN III, IV and VI activity

18
Q

What role does the SC have in eye movements?

A

Function of pathway is to orient head and eyes to visual stimulus to answer the question: Where is it?

19
Q

What are saccadic eye movements and how do they impact vision?

A

Saccades are quick, simultaneous movements of both eyes in the same direction initiated cortically by the cortical eye fields or by superior colliculus.

  • Reflexive saccade is triggered exogenously by peripheral stimulus to orient your vision
  • Scanning saccade is triggered endogenously for the purpose of exploring
20
Q

What is blindsight and how does it relate to the SC?

A

Lesion of primary visual cortex leads to complete lack of
consciousness of visual information
“extrastriate” midbrain pathway
Blindsight koniocellular pathway ganglion cells project to SC–>SC projects to pulvinar nucleus and from there to posterior parietal cortex (dorsal stream)

21
Q

What does the suprachiasmatic nucleus do?

A

SCN is a hypothalamic nucleus (just above the optic chiasm) and is the pacemaker of circadian rhythms
Melanopsin ganglion cells project to SCN.
SCN projects axons to paraventricular hypothalamic nuclei (PVN)

22
Q

How is melatonin released by the SCN?

A

SCN regulates PINEAL
release of MELATONIN
via the sympathetic
nervous system

23
Q

What impacts do melatonin have on the systems covered in class?

A

Melatonin regulates various organs, incl. sleep-wake cycles, temperature, and cortisol release
either directly or via action of the SCN
• Melatonin is released with a decrease in light; it is a sleep promoting factor

24
Q

ON vs OFF cells

A

WITh NO LIGHT
• OFF bipolar-ganglion cells are excited
• ON bipolar-ganglion cells are inhibited

The ON cells are inhibited and the OFF cells are
excited by differential release of glutamate

25
Q

Lateral genticulate Nucleus

A

• Visual thalamus
• Six-layered structure that receives input from each eye
in alternating layers
• Parvo- and magnocellular pathways project their small
and large center-surround receptive fields to different
sectors of the LGN

26
Q

visual cortex

A

Primary visual cortex (V1) on medial surface
of occipital lobe
Concentric cortical areas extend out from
primary visual cortex (V1) to association
visual areas V2, V3, V5.