Visual Neuropsychology Flashcards

1
Q

What is neuropsychology?

A
  • Neuropsychology is the study of behavioural problems of people with brain damage (for eg. stroke, trauma and cancer).
  • Behavioural experiments are used to understand what brain areas show the deficits associated with these problems
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2
Q

What does damage to prefrontal & orbitofrontal cortex cause?

A

Damage here causes social behaviour problems

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3
Q

Describe the frontal lobe and its disorders?

A
  • Represents large area of brain
  • 3 general anatomical divisions of frontal cortex: the limbic, the precentral and the prefrontal cortices.
  • Brain centers within the frontal lobe interconnected with other parts of the brain.
  • Emotion and Mood centres  lesion in frontal lobe – may not trigger feedback to visual cortex e.g. see car coming but have no fear of it & so don’t move out way
  • Cognitive centres.
  • Interconnected complexity results in a number of syndromes associated with lesions of this area
    Aphasia: inability to speak
    Acalculia: inability to calculate
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4
Q

What is Body Schema Disruption?

A

Lesions of Parietal lobes may produce characteristic disturbances of cognitive model representing knowledge about arrangement of body parts & their spatial relationship to objects in environment

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5
Q

What is the initial visual pathway?

A

Eyes, Optic Nerve, Optic Chiasm: Fibre crossover: separation of R & L VFs instead of R&L eyes

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6
Q

What is the middle visual pathway?

A
  • Middle Visual Path I: Geniculostriate Path
  • Optic chiasm
  • Lateral geniculate body of thalamus
  • Optic radiations
  • Calcarine fissure: primary visual cortex
  • Purpose is pattern analysis and colour perception
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7
Q

What problems are caused by damge to different parts of the visual pathway?

A
  • Retinal or other eye damage (e.g. macular degeneration, retinal stroke)
  • Monocular blindness: field cuts
  • Homonymous hemianopsias: bitemporal, nasal
  • Quadrantinopsias
  • Macular sparing – central vision unaffected
  • L optic nerve cut – no vision in LE but RE sees L VF
  • L optic tract cut – R VF loss in each eye
  • Optic chiasm split in middle – BEs lose peripheral vision – problems w/ binocularity as each eye seeing differently
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8
Q

What are the dorsal and ventral streams? (brief description)

A
  • Dorsal stream is pathway for visual info involved in spatial awareness: recognising where objects are in space.
  • Ventral stream is associated with object recognition & form representation. Has strong connections to the medial temporal lobe, the limbic system and the dorsal stream
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9
Q

Describe the problems which arise due to damage to the dorsal or ventral stream?

A
  • Visual Agnosias: Inability to recognise people or objects even when basic sensory modalities, such as vision, are intact.
  • Prosopagnosia: issue with faces
  • Agnostic Alexia: issue with reading material
  • Colour Agnosia: issue with colours (even if cones intact)
  • Object Agnosia: issue with objects (‘man who mistook wife for hat’)
  • Simultanagnosia: Inability to recognise a whole image although individual details are recognised
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10
Q

Describe prosopagnosia?

A
  • Inability to perceive faces, or face blindness.
  • Perceptual problem that stops people from being able to put the image of the face together as a whole.
  • Px will often try to use other clues e.g. clothes of the person
  • If test px’s VA it will be fine – they do not have issue recognising letters
  • Rare disorder & varies in intensity – one person with the disorder may not be able to recognise whether two pictures are of the same face or not, while in another patient recognition of one’s own family members is affected.
  • A most severe example of prosopagnosia is when one cannot recognise oneself in a photograph or in the mirror.
  • These skills do not improve with practice or familiarity. Usually it is not limited to the recognition of individuals, but also of more basic facts such as gender and facial expression.
  • An extreme form of both object agnosia and prosopagnosia was described by Oliver Sacks in his book ‘The man who mistook his wife for a hat.’
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11
Q

Describe Central Achromatopsia?

A
  • Refers to a loss of colour perception as a result of lesions of the optic nerve or occipital lobe.
  • The disorder can affect both VFs or a single hemi-field.
  • Patients are usually aware of the deficit and report the world as “grey”, or “dirty”.
  • Patients will correctly answer questions pertaining to colour concepts or descriptions of objects that include colour (e.g., “what is the colour of blood?).
  • Central achromatopsia may also affect one colour more than another may. Lesions of the fusiform gyrus of the medial occipital lobe are associated with this syndrome.
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12
Q

Describe simultanagnosia?

A
  • Simultanagnosia refers to inability to recognise two or more things at the same time.
  • Identification of some parts of an object helps patients to make inferences about the whole object
  • Dorsal Simultanagnosics may seem to be “blind” since they bump into objects that are close together. Motion may further impair their ability to perceive objects. They find it difficult to read or count because it involves more than one object at a time. Common cause: bilateral damage to the bilateral parieto-occipito region
  • Ventral simultanagnosia: inability to identify more than one object at a time. They can see more than one object at a time but cannot read or describe pictures. Common cause: damage to the left inferior temporo-occipital region
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13
Q

Describe the Visual Spatial Disorders Spatial Localisation?

A
  • Patients with visual spatial impairment have difficulty localising objects in 2 & 3D space. For e.g. patients with spatial disorder cannot determine if a pattern of dots presented on a card are the same or different than another pattern. They have difficulty judging distance from themselves to objects in space.
  • Stereopsis (binocular depth perception) is often impaired.
  • They also have difficulty matching directional orientation of objects. For e.g., it is difficult for these patients to judge whether two lines on a page have the same angular orientation.
  • These difficulties in judging direction and distance are maintained even when the information about the objects is presented by touch as well as vision.
    o Integration problem of >1 sensory problem
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14
Q

Describe visual spatial construction?

A
  • Patients have difficulty w/ construction activities that require spatial abilities. Include drawing, both copying as well as drawing to verbal command, and assembling 2 and 3D objects. This latter ability is usually examined with block puzzles.
  • The deficit extends to everyday activities that require assembling objects from basic elements: e.g. laying out a place setting at the table, assembling furniture or drawing a map to one’s house.
  • Although patients with visual spatial impairment show impairment on these tasks, the activities all require substantial motor skill and praxis.
  • Consequently, patients with lesions of other parts of the brain that subsume these functions will also have difficulty with spatial construction tasks –> feedforward & feedback
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15
Q

Describe visual neglect & hemineglect?

A
  • Pxs w/ Hemineglect syndrome can accurately perceive sensory information but behave as if it does not exist.
  • Since lesion usually affects only one hemisphere most neglect syndromes only involve sensory information on one side (i.e.. hemi).
  • Their primary sensory systems (e.g., vision) are intact, but they do not attend to or behave consistent with perception.
  • They behave as if they only perceive information from the unaffected side.
  • Patients with severe forms of hemi-neglect may even refuse to accept that the affected limbs even belong to them.
  • They may even complain that someone else’s leg is in bed with them. Patients with Hemineglect who are touched on the affected side may report being touched on the intact side. This error is called allesthesia.
  • Allesthesia may be present in any sensory modality (not just vision)
  • Common in stroke pxs
  • Speech & comprehension may be fine but vision affected
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16
Q

Describe hemispatial neglect (unilateral spatial neglect)?

A
  • Pxs w/ this type of neglect have difficulty orienting their bodies in space as well as solving problems that have a spatial or visual component.
  • In general, entire spatial array is compressed into the spatial portion represented by intact side of sensory perception
    o When asked to draw a symmetrical object, the side contralateral to brain lesion is left blank. When asked to draw a clock, pxs with hemispatial neglect will compress the lateral dimension of the circular clock face and draw all twelve numbers the one side ipsilateral to the brain lesion.
  • Pxs with this form of neglect also fail to orient objects in the space contralateral to the lesion
    o May only wash or dress one side of the body, and may eat only the food on one side of the plate. They may also read only words on the intact side of space. Writing production will also only cover the intact side of space. Inability to dress because of neglect is called “Dressing Apraxia”.
  • Hemi-spatial neglect is more frequent following right parietal lobe lesions. It has been theorised that the right hemisphere maintains the complete body schema and visual spatial array for both sides of space. However, the left hemisphere only maintains the right side of space.
  • When the right hemisphere is injured, there is a severe unilateral neglect of the left side of space. However, left hemisphere lesions result in far less neglect of the right side of space because the right hemisphere is able to mediate orientation and cognition involving both sides.
17
Q

Describe Parietal Neglect?

A
  • Involves supramarginal gyrus in inferior parietal lobe, at the temporoparietal junction
  • Exact extent of lesion will vary in individual cases
  • Persistent neglect is more common after right- than left-hemisphere lesions, for reasons of hemispheric specialisation in humans which remain poorly understood, but which may relate to right-hemisphere dominance for spatial cognition, for attention to global properties of visual scenes, and for arousal.
18
Q

Describe Balint’s syndrome? - how does it arise, what are the 3 cardinal symptoms, what other details do you know?

A
  • This syndrome results from injury of both parietal lobes. Consists of 3 cardinal symptoms:
    o 1) paralysis of gaze, in which the patient cannot look into the peripheral field.
    o 2) optic ataxia, in which the patient cannot use visual information to accurately co-ordinate actions – lag between vision & motor movement
    o 3) central fixation of dynamic visual attention, in which px has difficulty attending to peripheral fields when actively attending to environment.
  • Performance may be worse in one hemifield, usually the right.
  • Patients with Balint’s syndrome appear to neglect the peripheral parts of the VFs & have great difficulty integrating info from all parts of VFs into a whole perception.
    o For e.g., when shown a picture of common scene, such as a sporting event, they may only describe individual details, such as the clothing worn by one person.
    o Although they might describe numerous such details, they may never realise that the picture depicts a sporting event.
  • This ability to describe and recognise details but inability to recognise the whole visual array is called simultanagnosia.
  • The optic ataxia associated with Balint’s syndrome is manifested as difficulty estimating distances in visual space & co-ordinating actions consistent with the proper spatial arrangement.
    o For e.g., if pxs are asked to touch object with finger, they often point and miss. When asked to pour water from a pitcher to a glass, they invariably miss the glass.
19
Q

Describe cortical blindness?

A
  • If both occipital lobes are injured, then px is in a state of cortical blindness.
  • Px is unable to process visual info & behaves in a similar fashion to someone who suffers a peripheral blindness.
  • However, some pxs deny their blindness & attempt to behave as if they have vision.
    o This state of denial of cortical blindness is called Anton’s Syndrome.
    o Many pxs w/ Anton’s syndrome have associated parietal lobe lesions & sensory neglect.
    o They may deny sensory deficits in other modalities in addition to vision.
    o Some patients have a general dementia, and others are recovering from coma & delirium when they manifest denial of cortical blindness