Visual Impairment Flashcards

Learn how vision is disturbed

1
Q

How does visual impairment present to a Neurologist?

A

Normally involves a lesion in the visual pathway from the retina to the occipital cortex

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2
Q

What is the anatomical path of light through the eye?

A
  1. Retina to the optic nerve
  2. Optic nerve to the optic chiasm
  3. Optic chiasm to lateral geniculate nucleus
  4. Lateral geniculate nucleus to occipital cortex
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3
Q

The retina?

A
  1. Three neuronal levels: photoreceptors, bipolar and ganglion cells
  2. Rods: night vision/peripheral movement (In periphery)
  3. Cones: daytime/colour concentrated in macula
  4. Macula
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4
Q

What is the blood supply to the visual pathway?

A
  1. The opthalmic artery us the first branch of the internal carotid, gives rise to the central retinal and posterior ciliary arteries.
  2. Forms the blood supply to the retina and optic nerve.
  3. Optic radiations are supplied by the middle cerebral artery.
  4. The posterior cerebral artery supplies the lateral geniculate nucleus and the. occipital cortex
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5
Q

Name the lesions of the visual field defects?

A
  1. Monocular visual loss
  2. Bitemporal hemianopia
  3. Homonymous hemianopia
  4. Homonymous inferior quadrantanopia
  5. Homonymous superior quadrantanopia
  6. Homonymous hemianopia with macular sparing
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6
Q

Describe an optic nerve lesion?

A
  1. Impaired vision in one eye
  2. O/E reduced visual acuity, reduction of colour vision and a central scotoma
  3. An afferent pupillary defect may be present.
  4. If lesion is longstanding vision maybe lost in affected eye and optic disc becomes pale.
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7
Q

Describe an optic chiasm lesion

A
  1. Causes bitemporal hemianopia, involving decussating fibres.
  2. Pressure from a lesion below the chiasm ie a pituitary tumour will cause bitemporal superior quadrantanopia.
  3. Pressure from above will cause an inferior quadrantanopia
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8
Q

Lesions of the optic chiasm include:

A
  1. Tumours, eg pituitary adenoma, meningioma, craniopharyngioma, or metastatic deposits
  2. Cerebral aneurysm
  3. Granulomatous disease, TB, sarcoidosis
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9
Q

Optic tract and optic radiation lesions

A
  1. Cause a contralateral homonymous quadrantanopia.
  2. Those involving the parietal fibres give an inferior quadrantanopia.
  3. Those involving the temporal lobe fibres give rise to a superior quadrantanopia
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10
Q

Lesions of the optic tract and optic radiation include:

A
  1. Infarction, such as a lesion of the middle cerebral artery
  2. Intra cerebral hemorrhage
  3. Tumours
  4. Trauma
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11
Q

Occipital cortex lesions

A
  1. Unilateral lesions of the posterior cerebral artery, embolism from vertebrobasilar arterial tree causes a contralateral homonymous hemianopia.
  2. Bilateral occipital damage gives rise to cortical blindness.
  3. Visual loss throughout the field in both eyes but preserved pupillary response
  4. Patient can be unaware of blindness.
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12
Q
Differential diagnosis:
1. Temporal pattern
2. Mode of onset
3. Subsequent course
Determine if:
1. Transient
2. Persistent
A

Acute Transient Visual Impairment:

  1. Amaurosis fugax
  2. Migraine with aura
  3. Papilloedema
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13
Q

What is Amaurosis Fugax

A
  1. Patient complains of unilateral latitudinal visual loss, shutter coming down. Lasts several seconds followed by recovery.
  2. Caused by atheroma of ipsilateral carotid artery, causing embolism into central retinal artery and its distal branches.
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14
Q

What is migraine with aura?

A
  1. Visual symptoms - flashing lights, lines etc
  2. Diagnosis made from history of paroxysmal attacks with headache nausea vomiting.
  3. Can get focal symptoms eg tingling hands etc
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15
Q

What is papilloedma?

A
  1. Swelling of the optic disc due to raised intracranial pressure.
  2. Optic nerve covers by meninges, hence covered with subarachnoid fluid.
  3. Raised intracranial pressure impedes venous drainage and axoplasmic flow.
  4. O/E visual acuity normal, but blind spot enlarged, restriction of peripheral field of vision.
  5. Disc is swollen, retinal veins engorged, flame shaped hemorrhages, optic atrophy.
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16
Q

Describe Acute Persistent Visual Impairment?

A
  1. Optic neuritis
  2. Retinal or optic nerve ischemia
  3. Arterial thromboembolism of middle or posterior cerebral artery
17
Q

What is Optic Neuritis

A
  1. Inflammation of the optic nerve
  2. Anterior involvement causes visible swelling
  3. Posterior involvement and optic disc looks normal
  4. Dull ache
  5. Central scotoma
  6. Most common cause is demyelination of optic nerve or MS.
18
Q

What is retinal or optic nerve ischemia?

A

Sudden monocular visual loss results from embolism into the central retinal artery or occlusion of small posterior ciliary arteries by local small vessel disease or inflammation.

19
Q

Describe arterial thromboembolism of the middle or posterior cerebral artery.

A
  1. Homonomous hemianopia or quadratanopia present
  2. History an exam should focus on cerebrovascular risk factors, ischaemic heart disease, diabetes, hyperlipidaemia, hypertension and atrial fibrillation.
20
Q

What is Optic atrophy

A
  1. Results from damage to nerve fibres in the visual pathways at any point between and including the ganglion cells of the retina and the lateral geniculate nucleus.
  2. Vision loss is central and peripheral.
21
Q

Causes of retinal atrophy

A
  1. Retinal disease, retinal artery occlusion
  2. Optic nerve: optic neuritis, chronic glaucoma, papilloedaema, tumours, metabolic deficiencies
  3. Chiasm and optic tract: pituitary tumours and craniopharyngioma