Viruses & Prions Flashcards
1
Q
Capsomers
A
Individual proteins that make up a capsid.
2
Q
Capsid
A
Holds viral genome (nucleic acid) inside.
- The basic unit of virion structure (simplest it can get).
3
Q
Nucleocapsid
A
Holds (capsid + genome)
4
Q
Envelope
A
Surrounds nucleocapsid
5
Q
Virion
A
Entire Virus Particle
6
Q
Icosahedral Protein Coat
A
Spherical protein coat/capsid which limits the size of nucleic acid.
7
Q
Helical Protein Coat
A
Rod-shaped protein coat/capsid with no limit to the amount of nucleic acid that can fit in.
8
Q
Characteristics of Enveloped Viruses
A
- Envelope from host cell phospholipid membranes (golgi or plama).
- Contains virally encoded structural proteins called glycoproteins or host cell proteins.
- Sensitive to heat, acids, drying
- Less associated with GI diseases (stomach acid will melt them)
9
Q
DNA Viruses
몸에 남아있다가 면역력 약해지면 잘 나오는 애들
A
** Herpesviruses: Enveloped viruses with ds DNA
- Herpes Simplex Type 1 & 2 (HSV)
- Varicella Zoster Virus (VZV)
- Cytomegalovirus (CMV)
- Epstein Barr Virus (EBV)
10
Q
RNA Viruses
유행탔던 바이러스들
A
- Influenza (-ssRNA)
- Coronavirus (+ssRNA)
- HIV (+ssRNA)
11
Q
Characteristics of Non-Enveloped (Naked) Viruses
A
- Outer covering is capsid protein.
- Often lysis the host cell
- Resistant to heat, acids, drying
- Associated with GI tract
- Examples: Norovirus, rotavirus
12
Q
Coronavirus
A
Virus Name: SARS-CoV-2
Disease Name: COVID-19
13
Q
HSV-1 & HSV-2
A
- Cause oral & gential herpes
- can cause complications such as encephalitis, hepatitis
14
Q
VZV
A
- Chickenpox as primary infection
- Shingles as reactivation
15
Q
CMV
A
- usually asymptomatic but can cause mono
