Viruses and the FLU Flashcards

1
Q

Name a virus that is transmitted through the skin via trauma?

A

Human papiloma virus → warts.

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2
Q

Name viruses that are transmitted through the skin via insects?

A

Dengue fever → a type of Flavivirus,
yellow fever → a type of Flavivirus,
West Nile disease → a type of Flavivirus
Zika virus → a type of Flavivirus

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3
Q

Name viruses that are transmitted through the skin via needle stick injury?

A

HIV → Human immunodeficiency virus: Lentivirus
Hep B → Hepatitis B virus
Hep C → Hepatitis C virus

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4
Q

Name a virus that is transmitted through the skin via an animal bite?

A

Rabies → a neurotropic virus

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5
Q

Name a virus that is transmitted via the mucus membranes of the genitles?

A

HSV → Herpes simplex virus
HIV → Human immunosuppresant virus
CMV → Cytomegalovirus (herpes family)

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6
Q

Name a virus that is transmitted via the mucus membranes of the respiratory tract?

A

FLU → Influenza virus
Measles virus
Chickenpox → Vricella zoster virus. also causes shingles.
Mumps → Rubulavirus
Epstein-barr virus → mono/galandular fever
Coronavirus → MERS (middle eastern respiratory syndrome)

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7
Q

Name a virus that is transmitted via the mucus membranes of the GI tract?

A

Hep A → hepatitis A virus
Polio virus → poliomyelitis
Rotaviruses

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8
Q

Name a virus that is transmitted via the mucus membranes of the eye?

A

HSV → herpes simplex virus

Adenoviruses → conjunctivitis

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9
Q

Name a virus that is spread via the feacle oral route?

A

Norovirus → nothing stays in me.

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10
Q

Viruses affecting the upper respiratory tract (oro and naso-pharynx) causing Rhinitis, Pharyngitis and Laryngitis?

A
Rhinovirus
Coronavirus
Parainfluenza virus
Respiratory syncytial virus
Influenza Virus
Adenovirus
Herpes simplex virus
Epstein-Barr virus
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11
Q

Viruses affecting the lower respiratory tract causing tracheitis, Bronchitis, Bronchiolitis and Bronchopneumonia

A

Parainfluenza virus
Respiratory syncytial virus (RSV)
Influenza Virus
Adenovirus

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12
Q

What is the “achiles heel” of the gut called?

A

Peyers patches and colonic lymphoid aggregations. Viruses enter and are taken up by leukocytes and then spread throughout the body via lymphatic dainage.

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13
Q

give 2 examples of a localised viral infection?

A

Flu and Warts.

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14
Q

Give 2 examples of systemic viral infection?

A

polio and Hep B

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15
Q

In a flu virus H5N1, what do the “H” and the “N” stand for?

A

haemagglutinin and neuraminidase

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16
Q

name 5 types patterns of viral infection?

A

Acute, Chronic, latent, Subclinical and insidious

17
Q

What do viruses do to a human host?

A

Viruses invade cells. They do this in order to replicate. they take cells over and turn them into virus factories.

18
Q

When we are sick with a virus what causes our symptoms?

A

t-cell mediated response.

19
Q

What is used to treat the herpes simplex and varicella zoster viruses?

A

Aciclovir - most effective in early symptoms.

20
Q

What is used to treat CMV (cytomegalovirus)?

A

Ganciclovir

21
Q

What are the 2 types of viruses?

A

naked viruses and enveloped viruses

22
Q

What are the 3 types of neucloplasmid symmetry?

A

Icosahedral, helical and complex

23
Q

What are 3 examples of an icosahedral Virus?

A

HSV, Polio and Parvo virus

24
Q

What are 2 examples of helical viruses?

A

HIV and measles.

25
Q

What is an example of a complex virus?

A

Influenza

26
Q

What is the viral life cycle, How many steps does it have and what are they?

A
  1. Attachment/
  2. Penetration/Uncoating
  3. Transcritption/translation
  4. Genome replication
  5. Assembly/maturation
  6. release
27
Q

What are the 3 routes of viral penetration into a cell?

A
  • Viral translocation → only occurs with naked viruses
  • surface fusion → enveloped viruses only
  • receptor mediated endocytosis → most common form of viral entry to a cell
28
Q

What is the method of action of effective antivirals?

A

Neuraminidase inhibitors.