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Unit 4 Micro Pathogens > Viruses And prions > Flashcards

Viruses And prions Flashcards

1
Q

What is a DNA virus that is enveloped

A

Herpes Simplex Virus

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2
Q

HSV-1 prefers to be in the?

A

Oral mucosa

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3
Q

HSV-1 causes

A

Oral herpes

genital herpes

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4
Q

HSV-1 transmission

A

Oral secretions

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5
Q

HSV-1 Pathogenesis

A
  • Infects cells around site of entry (oral mucosa)
  • Remains latent in trigeminal nerve ganglia
  • Can travel back to oral mucosa —>active infection
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6
Q

HSV-1 activation is associated with :

A

UV light
Emotional Stress
Mensuration

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7
Q

Oral herpes Signs/symptoms

A

Cold sores: painful, short-lived vesicles on outer margin of lips

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8
Q

Oral herpes DX

A

Clinical assessment

Nucleic acid infection

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9
Q

Oral herpes Tx

A

Acyclovir & Valacyclovir

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10
Q

HSV-2 prefers to be in ?

A

Genital mucosa

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11
Q

HSV-2 causes

A

Genital herpes

Oral herpes

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12
Q

HSV-2 transmission

A

Sexual conduct

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13
Q

HSV-2 Pathogenesis

A
  • Infects cells around site of entry (genital mucosa)
  • Remains latent in sacral nerve ganglia
  • Can travel back to genital mucosa —> active infection
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14
Q

HSV-2 activation Is associated with ?

A

Emotional distress

Menstruation

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15
Q

Genital Herpes Signs/symptoms

A

Vesicles on genitals

Burning during urination

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16
Q

Genital herpes DX

A

Clinical assessment

Nucleic acid identification

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17
Q

Genital herpes Tx

A

Acyclovir

Valacyclovir

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18
Q

RNA virus that is enveloped

A

Rabies virus

19
Q

Rabies virus causes ?

A

Rabies

20
Q

Rabies virus transmission

A

Saliva from bite of infected animal

21
Q

Rabies virus most common reservoirs ?

A

Raccoons, skunks, bats

22
Q

Rabies pathogenesis

A

-Rabies virus injected into body —> enter
muscle cells and replicate
-Rabies virus enters motor neuron and
travels to CNS —>brain
-Rabies virus can travel to salivary glands
and other organs

23
Q

Rabies signs/symptoms

A

Tingling around bit, muscle spasms, weakness, fever

24
Q

What are the two forms of clinical rabies

A

Furious rabies

Paralytic rabies

25
Q

Genital Warts signs/symptoms

A

Bumps of genitals

26
Q

Genital warts DX

A

Clinical assessment

Nucleic acid identification

27
Q

Genital warts Tx

A

Gels for warts (not antivirals)

28
Q

Human papilloma virus Pathogen

A

Infects epithelial cells

29
Q

HOV-6 and HPV-11

A

DNA remains extra chromosomal

Infected cells increase keratin production

30
Q

HPV-16 and HPV-18

A

DNA integrates into host cell’s chromosome

HPV-16 and -18 DNA encode proteins that suppress host cell tumor suppressor proteins

31
Q

Human Papillomavirus (HPV)

A

Over 200 types
DNA viruses
Non-enveloped

32
Q

HPV cause genital warts

Most common?

A

HPV-6 & HPV-11

33
Q

HPV Can cause cancer

Most common ?

A

HPV-16 & HPV-18

34
Q

HPV transmission

A

Sexual contact

35
Q

Some virus contains oncogenes that means ?

A

Oncogenic viruses

36
Q

Oncogenic virus :

A

Human papilloma virus

37
Q

Cancer is caused by

A

Mutagens
Viruses
Inherited

38
Q

Oncogene

A

gene with ability to convert normal cell to

cancer cell

39
Q

Cancer

A

Abnormal cells divide uncontrollably

40
Q

Rabies Dx

A

Nucleic acid identification

Negri bodies in cytoplasm of nerve cells

41
Q

Rabies Tx

A

start ASAP after bite from infected animal)

  • Rabies vaccine + immune globulin injections
  • Once clinical rabies signs/symptoms appear, treatment is usually ineffective
42
Q

Paralytic rabies signs/symptoms

A

Muscle paralysis
Viral encephalitis
Coma

43
Q

Furious Rabies signs/symptoms

A

Hydrophobia
Excessive salivation
Aggression
Viral encephalitis

Unit 4 Micro Pathogens (1 decks)

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