VIRUSES Flashcards
Pox virus
Smallpox
Cowpox (milkmaid blisters)
Molluscum contagiousum
LARGEST DNA VIRUS
Parvovirus
B19 virus- aplastic crises in SCD, ‘slapped cheek’ rash in children
RBC destruction in children- hydrops foetalis- death
Adults- pure RBC aplasia and rheumatoid arthritis- like symptoms
SMALLEST DNA VIRUS
Hepadnavirus
HBV
Adenovirus
Febrile pharyngitis- sore throat Acute hemorrhagic cystitis Pneumomia Conjunctivitis- pink eye Gastroenteritis Myocarditis
Papillomavirus
HPV- warts (stereotypes 1, 2, 6, 11) Cervical cancer (16, 18) CIN
Polyomavirus
JC Virus- progressive mulifocal leukoencephalopathy in HIV
BK Virus- transplant patients, commonly target kidney
JC Juncky Cerebrum
BK Bad Kidney
HSV- 1
Respiratory secretions, saliva Gingivostomatitis Keratoconjunctivitis Herpes labialis Herpetic whitlow on finger Temporal lobe encephalitis Esophagitis Erythema multiforme Latent in trigeminal ganglia
HSV- 2
Sexual contact, perinatal
Herpes genitalis
Neonatal herpes
Latent in sacral ganglia
Varicella Zoster virus
Respiratory secretions
Varicella- zoster ( chicken pox, shingles( post herpatic neuralgia))
Encephalitis
Pneumonia
Latent in dorsal root or trigeminal ganglia
CN V1 - herpes zoster ophthalmicus
Epstein Barr virus
Respiratory secretions, saliva
Mononucleosis- feved, hepatosplenomegaly, pharyngitis, lymphadenopathy (post cervical nodes)
+ monospot test
Cytomegalovirus
Congenital, transfusion, sexual contact, saliva, urine, transplant
Mononucleosis; - monospot test in immunocompetent patients
Pneumonia in transplant patients
AIDS retinitis: hemorrhage, cotton wool exudates, vision loss
Owl eye intranuclear inclusions
HHV- 7
Saliva
Roseola infantum- fever first, rash later
HHV-8
Sexual contact
Kapsoi sarcoma- neoplasm of endothelial cells, seen on HIV/AIDS and transplant patients
Reoviruses
Coltivirus å- Colorado tick fever
Rotavirus- fatal diarrhoea in children
å- arbovirus, arthropod borne (mosquitoes, ticks)
Picornaviruses
PERCH Poliovirus- polio Echovirus- aseptic meningitis Rhinovirus- common cold Coxsackievirus- aseptic meningitis, herpangina (mouth blisters, fever), hand, foot and mouth disease, myocarditis, pericarditis HAV- acute viral hepatitis