Viruses Flashcards
Regressive Hypothesis
The “devolution” from free-living cells
Progressive hypothesis
Nuclei acid molecules “escaped” from cells
Virus first hypothesis
The first self-replicating molecules
Virion structure
Nucleic acid core and capsid
Other: glycoproteins, outer envelope, enzymes
Nucleic acid core
DNA (double stranded or single) or RNA
Capsid
Protein coating protecting the genetic material
Capsid shape
Made up of capsomeres
Helical, icosahedral, complex
Enveloped capsid structure
Capsid encased in lipid bilateral membrane from host cell
Naked capsid structure
Lack membrane
Virus core DNA genome
DNA directs the host cell to make new virus copies
Virus core RNA genome
RNA meh be directly transcribed or replicated first, enzymes are used to make errors and mutate frequently
Challenges of viruses
Most viruses evolved from different ancestors and no common genomic sequence.
Classify
Capsid structure
Enveloped/ non-enveloped
Genomic structure
Baltimore classification
Different modes of mRNA production
Lysis
The cell ruptures-dies