Viruses Flashcards

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1
Q

Regressive Hypothesis

A

The “devolution” from free-living cells

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2
Q

Progressive hypothesis

A

Nuclei acid molecules “escaped” from cells

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3
Q

Virus first hypothesis

A

The first self-replicating molecules

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4
Q

Virion structure

A

Nucleic acid core and capsid

Other: glycoproteins, outer envelope, enzymes

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5
Q

Nucleic acid core

A

DNA (double stranded or single) or RNA

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6
Q

Capsid

A

Protein coating protecting the genetic material

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7
Q

Capsid shape

A

Made up of capsomeres
Helical, icosahedral, complex

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8
Q

Enveloped capsid structure

A

Capsid encased in lipid bilateral membrane from host cell

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9
Q

Naked capsid structure

A

Lack membrane

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10
Q

Virus core DNA genome

A

DNA directs the host cell to make new virus copies

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11
Q

Virus core RNA genome

A

RNA meh be directly transcribed or replicated first, enzymes are used to make errors and mutate frequently

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12
Q

Challenges of viruses

A

Most viruses evolved from different ancestors and no common genomic sequence.

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13
Q

Classify

A

Capsid structure
Enveloped/ non-enveloped
Genomic structure

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14
Q

Baltimore classification

A

Different modes of mRNA production

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15
Q

Lysis

A

The cell ruptures-dies

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16
Q

Apoptosis

A

Programmed self-destruction - dies

17
Q

Steps of virus infection

A
  1. Attachment
  2. Entry
  3. Replication
  4. Assembly
  5. Egress
18
Q

Attachment

A

Lock and key system