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Virology Finals > Viruses > Flashcards

Viruses Flashcards

1
Q

Tacaribe, Guanarito, Junin and Machupo

A

New world Arena virus

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2
Q

Mus musculus
Mastomys natalensis

A

Old world Arena virus

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3
Q

Meningitis

A

Lymphocytic Choriomeningitis

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4
Q

hemorrhagic fever + influenza like

A

Lassa Virus

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5
Q

Sand shape appearance in electron microscope

Acquired through inhalation from infected rodent or direct contact

A

Arenavirus

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6
Q

Transmitted by mosquito, ticks and sandfly

A

Bunyavirus

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7
Q

LaCrosse & California Encephalitis

A

Brain and liver

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8
Q

Hemorrhagic Fever

A

Vascular Endothelium and Liver

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9
Q

Small( 30 to 38) nm rounded nonenveloped that cause gastroenteritis to humans

A

Calcivirus

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10
Q

acquired from civet cat that originated from Guangdong, China

A

SARS-COV1

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11
Q

possibly acquired from pangolin that originated for Wuhan, China.

A

SARS-COV2

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12
Q

Aedes aegypti, Aedes albopictus and Aedes polynesiansis.

A

Dengue vectors

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13
Q

Major protein in dengue virus

A

E for envelope protein

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14
Q

Previously under calicivirus;

High Case Fatality Rate in Pregnant Women
( 10-20%)

A

Hepevirus

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15
Q

Do not have segments that’s why they don’t undergo antigenic shift

A

Paramyxovirus

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16
Q

Highly contagious accompanied by maculopapular rash and fever

A

Measles or Morbilivirus

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17
Q

Associated with winter epidemics bronchiolitis and pneumonia which is common in children

A

Metapneumovirus

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18
Q

The most common cause of aseptic meningitis or inflammation of brain parenchyma

Primary MOT: respiratory or gastrointestinal

A

Enteroviruses

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19
Q

NAKED virus

A

PIcornavirus, REovirus, CAlicivirus,PApovavirus, PArvovirus, ADEnovirus

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20
Q

Protein shell or coat that encloses the nucleic acid

A

Capsid

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21
Q

Nucleic acid + Capsid (Enclosed)

A

Nucleocapsid

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22
Q

Morphological units seen on the surface of particles

A

Capsomeres

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23
Q

A lipid containing membrane that surrounds some viral particles

A

Envelope

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24
Q

Protomers are the smallest functional unit equivalent to building units of the capsid

A

Structural Units

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25
Q

Shell vial

A

Cell culture

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26
Q

Derived from animals

A

Primary cell culture

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27
Q

derived from embryonic tissues

A

Semi-continuous cell culture

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28
Q

derived from tumor or malignant tissues

A

Continuous cell culture

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29
Q

Largest DNA virus

A

Poxivurs

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30
Q

Smallest DNA virus

A

Parvovirus

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31
Q

All are double stranded DNA virus EXCEPT

A

Parvovirus

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32
Q

All DNA virus are icosahedral Except

A

Poxvirus

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33
Q

All DNA virus are enveloped Except

A

PAvovavirus, ADEnovirus, PArvovirus

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34
Q

DNA virus that multiplies in cytoplasm

A

Poxvirus

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35
Q

Grape like cluster

A

Adenovirus

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36
Q

DNA virus: Gastroenteritis in children

A

Adenovirus serotype 40 and 41

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37
Q

Recurrence of skin lesion after primary infection

A

HSV1 and HSV 2

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38
Q

Latency: SENSORY NERVE GANGLIA

A

HSV1 and HSV 2

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39
Q

Cold sores or Fever blisters, Gingivostomatitis, Herpes Labialis, Keratitis, Pharyngitis, Herpetic Whitlow, Encephalitis

A

HSV1

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40
Q

Genital infection

A

HSV2

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41
Q

Transmitted through personal contact especially respiratory

A

VARICELLA ZOSTER VIRUS

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42
Q

Chicken pox

A

Varicella

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43
Q

Zoster

A

Shingles

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44
Q

Presence of skin rash with blisters that look like skin rashes, dew drops in a rose petal

A

Varicella Zoster

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45
Q

Transmitted through saliva

A

Epstein barr/HHV4

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46
Q

Causative agent of Infectious mononucleosis ( Glandular Fever), Burkitt lymphoma and Nasopharyngeal carcinoma

A

Epstein barr/HHV4

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47
Q

latency: B VIRUS

A

Epstein barr/HHV4

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48
Q

Salivary gland virus

Bull’s eye

A

CYTOMEGALOVIRUS/ HHV-5

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49
Q

Transmitted through close contact with secretions, blood transfusion (WBC), organ transplant and transplacenta

Viral mental retardation and congenital disease

A

CYTOMEGALOVIRUS/ HHV-5

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50
Q

Transmitted through respiratory secretions; almost all children from age 2-3 years old

Latency: CDS/T HEPLER CELLS

A

HUMAN HERPES VIRUS-6(HHV-6) AND HHV 7

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51
Q

Fever w/ short rash

A

Lymphotropic virus and Roseola (Exanthem subitum)

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52
Q

Kaposi Sarcoma

A

Rhadinovirus/HHV8

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53
Q

Cause warts and exhibit tropism in cutaneous and mucocutaneous

A

Papillomavirus

54
Q

plantar warts

A

HPV1

55
Q

Warts of the Hand

A

HPV2 and HPV4

56
Q

Genital warts

A

HPV6 and HPV11

57
Q

Epidermodysplasia verruciformis

A

HPV5 and HPV8

58
Q

Hecks’s Disease/Pocal epithelial hyperplasia

A

HPV13 and HPV32

59
Q

Condyloma Acuminata

A

HPV16 and HPV18

60
Q

Subset cancer of oropharynx and penile cancer in Men

A

HPV16

61
Q

Viral replication sites are erythroid progenitor cells, adult bone marrow and fetal liver

A

Parvovirus B19

62
Q

associated with Merkel cell Carcinoma

A

MC virus

63
Q

Progressive multifocal leukoencelopathy; latent state in lymphocytes

A

JC Virus/ Polyoma virus hominis 2

64
Q

causes hemorrhagic cystitis; latent state in kidney

A

BK Virus/ Polyoma virus hominis 1

65
Q

Oval or brick shape virus

A

Poxvirus

66
Q

causative agent of small pox virus

A

Variola/ Orthopoxvirus

67
Q

small, pink, papular, wart- like benign tumors of the skin or mucous membrane

A

Molluscum Contagiosum

68
Q

transmitted by direct contact with sheep in which nodules in hands may be seen

A

Orf virus

69
Q

Largest DOUBLE STRANDED DNA virus which is the causative agent of African Swine Flu ( ASF)

A

Iridovirus

70
Q

Not transmissible to human but highly pathogenic to pigs

Known to be transmitted by arthropods (soft ticks)

A

African Swine Flu

71
Q

All RNA VIRUS are single stranded EXCEPT

A

REovirus

72
Q

All RNA virus are enveloped EXCEPT:

A

PIcornavirus, CAlicivirus and REovirus

73
Q

All RNA VIRUS are generally helical EXCEPT:

A

PIcornavirus, REovirus, RETrovirus, FLAvivirus, TOgavirus

74
Q

All RNA VIRUS replicate in cytoplasm Except

A

ORthomyxovirus, REtrovirus

75
Q

Largest RNA VIRUS

A

Paramyxovirus

76
Q

Smallest RNA VIRUS

A

Picornavirus

77
Q

Arthropod borne

A

Majority of Bunyaviridae, Flaviviridae, and Togaviridae

78
Q

All Bunyaviridae are arthropod borne EXCEPT

A

Hantavirus

79
Q

All FLAVIVIRIDAE are arthropod borne EXCEPT

A

Hepatitis C

80
Q

All TOGAVIRIDAE are arthropod borne EXCEPT

A

Rubella

81
Q

Rodent borne

hemorrhagic fever with
renal syndrome(HFRS)

A

Hanta

82
Q

Small (30 to 38 nm) rounded nonenveloped

Causes gastroenteritis to humans

A

Calicivirus

83
Q

Associated with 80% of nonbacterial acute
gastroenteritis in undeveloped countries

A

Norovirus/Norwalk Virus

84
Q

cup shaped in EM that is also associated with
gastroenteritis

A

Sapovirus

85
Q

acquired from camel that originated in
middle east

A

MERS-COV

86
Q

Microscopy/viral nucleic acid

A

SARS-COV2 DIRECT Detection

87
Q

Serological testing

A

SARS-COV2 INDIRECT Detection

88
Q

Alpha B117

A

United kingdom

89
Q

Beta B1351

A

South Africa

90
Q

Gamma P1

A

Brazil

91
Q

Delta B16172

A

India

92
Q

Filo or threadlike due to long filamentous morphology in EM

Most pathogenic of the hemorrhagic virus

A

FILOVIRUS

93
Q
  • 25% fatality rate
  • Acquired from fruit bats
A

Marburg hemorrhagic fever virus

94
Q

*Emerging virus due to eating of African green monkey in Africa
*Acquired through direct contact with infected animal or human
*80% fatality rate

A

Ebola virus

95
Q

*Derived from flavus which means yellow

A

Flavivirus

96
Q

Aedes aegypti, Aedes albopictus and
Aedes polynesiansis

A

Dengue vectors

97
Q

transmitted by Culex mosquitoes and mostly in summer months

A

St. Louis Encephalitis

98
Q

*Spread by daytime Aedes aegypti and albopictus
*There is preliminary evidence, that Zika is a cause of Guillain-Barré syndrome in adults.

A

Zika virus

99
Q

*Vector is Culex mosquitos
*Maintained in bird-mosquito cycle such as crows, ravens

A

West Nile Virus

100
Q

Chronic liver disease

A

Hepa C

101
Q
  • Previously under calicivirus;
  • High Case Fatality Rate in Pregnant Women (10-20%)
A

Hepe virus

102
Q
  • Transmitted through respiratory secretions
A

ORTHOMYXOVIRUS

103
Q

rod-shaped spikes

A

Hemagglutinins

104
Q

mushroom-shaped spikes

A

Neuraminidase

105
Q

Spanish flu

A

H1N1

106
Q

H2N2

A

Asian Flu

107
Q

Hongkong Flu

A

H3N2

108
Q

H5N1

A

Avian flu

109
Q

Don’t undergo antigenic shift

A

PARAMYXOVIRUS

110
Q

Characterized by inflamed salivary gland accompanied by high temperature and fatigue

A

Mumps/Rubulavirus

111
Q

Second cause of pneumonia and bronchiolitis in children after RSV

A

Parainfluenza virus

112
Q

Most significant cause of acute RTI in children under 5 years of age worldwide

A

Respiratory Synctial Virus ( RSV) or Pneumovirus

113
Q
  • Highly contagious accompanied by maculopapular rash and fever
A

Measles or Morbilivirus

114
Q

Associated with winter epidemics bronchiolitis and pneumonia which is common in children

A

Metapneumovirus

115
Q

Consists of single-stranded RNA and viral Protein

A

PICORNAVIRUS

116
Q

The most common cause of aseptic meningitis or inflammation of brain parenchyma.

A

Enterovirus

117
Q
  • It is the major cause of cold virus
  • Resistant to detergents, lipid solvents, and temperature extremes but sensitive to pH less than 6.
A

Rhinovirus

118
Q
  • The most common cause of viral gastroenteritis in infants and children worldwide
A

Rotavirus

119
Q

Associated with Colorado tick fever

A

Coltivirus

120
Q

HTLV1

A

T cell leukemia

121
Q

Hairy cell leukemia

A

HTLV2

122
Q

HIV

A

Causative agent of AIDS

123
Q

Screening of HIV

A

ELISA

124
Q

Confirmatory of HIV

A

WB

125
Q

Worldwide prevalence

A

HIV1

126
Q

HIV2

A

West Africa

127
Q

*Bullet shaped appearance

*It is characterized by saliva frothing with painful spasm

*May lead to coma or death

*Associated with negri bodies in brain tissues of infected animals and humans

A

Lyssavirus/ Rabies

128
Q

associated with equine encephalitis and
transmitted by mosquitos

A

Alphavirus

129
Q

may lead to congenital defect if pregnant
women is infected

A

German measles

130
Q

associated with myositis and arthritis which is transmitted by Aedes aegypti

A

Chikungunya virus

Virology Finals (1 decks)

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