Virus Virology Flashcards

1
Q

Herpesvirus:
what viruses are in this family
envelope?
genome structure?

A
HSV1, HSV2
VZV (HHV3)
EBV (HHV4)
CMV (HHV5)
HHV6&7- Roseola
HHV8- Kaposi

yes envelope
DS linear DNA

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2
Q

Hepadnavirus:
what viruses are in this family
envelope?
genome structure

A

HBV
yes envelope
partially dsDNA and circular

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3
Q

adenovirus:
what viruses are in this family
envelope?
genome structure

A

causes febrile pharyngitis (sore throat), acute hemorrhagic cystitis, pneumonia and conjunctivitis (think of that guy on p158 with the scary red eyes)

NO envelope
dsDNA and linear

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4
Q

parvovirus:
what viruses are in this family
envelope?
genome structure

A

B19-aplastic crisis in sickle and slapped cheeks in children

NO envelope
ssDNA and linear (only DNA virus that is SS). this is also the smallest DNA virus

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5
Q

papillomavirus:
what viruses are in this family
envelope?
genome structure

A

HPV

NO envelope
ds and circular DNA

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6
Q

polyomavirus:
what viruses are in this family
envelope?
genoma structure

A

JC virus- causes PML in HIV patients
BK virus- transplant patients targets kidney

NO envelope
dsDNA and circular

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7
Q

Poxvirus:
what viruses are in this family
envelope?
genome structure

A

smallpox
cow pox (milkmaid blisters)
molluscum contagiosum

YES envelope
dsDNA and linear (this is the largest DNA virus)

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8
Q

what is special about poxvirus replication

A

replicates in cytoplasm instead of nucleus where most DNA viruses replicate

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9
Q
Reovirus:
what viruses are in this family
envelope?
genome structure
capsid symmetry
A

rotavirus

NO envelope
dsRNA linear, segmented (only RNA virus that is double stranded)
capsid is double icosahedral

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10
Q
picornaviruses:
what viruses are in this family (5)
envelope?
genome structure
capsid symmetry
A

poliovirus, echovirus, rhinovirus, coxsakievirus, HAV

NO envelope
+ssRNA linear
icosahedral capsid

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11
Q
hepevirus:
what viruses are in this family
envelope?
genome structure
capsid symmetry
A

HEV

NO envelope
+ssRNA linear
icosahedral capsid

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12
Q
caliciviruses:
what viruses are in this family
envelope?
genome structure
capsid symmetry
A

norovirus

NO envelope
+ssRNA linear
icosahedral capsid

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13
Q
flaviviruses:
what viruses are in this family (5)
envelope?
genome structure
capsid symmetry
A
HCV
yellow fever
dengue
st. louis encephalitis
west nile

yes envelope
+ssRNA linear
icosahedral capsid

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14
Q
togaviruses:
what viruses are in this family
envelope?
genome structure
capsid symmetry
A

rubella, EEE, WEE

yes envelope
+ssRNA linear
icosahedral capsid

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15
Q
retrovirus:
what viruses are in this family
envelope?
genome structure
capsid symmetry
A

HTLV, HIV

yes envelope
+ssRNA linear two copies
icosahedral-HTLV and complex/clonical for HIV

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16
Q

what is the only RNA virus that replicates in the nucleus

A

retroviruses

17
Q
coronaviruses:
what viruses are in this family
envelope?
genome structure
capsid symmetry
A

coronavirus (common cold), sars

YES envelope
+ssRNA linear
helical capsid

18
Q
orthomyxoviruses:
what viruses are in this family
envelope?
genome structure
capsid symmetry
A

influenza

YES envelope
-ssRNA SEGMENTED
helical capsid

19
Q
paramyxovirus:
what viruses are in this family (4)
envelope?
genome structure
capsid symmetry
A

parainfluenza (croup)
RSV
measles, mumps

YES envelope
-ssRNA linear
helical capsid

20
Q
rhabdoviruses:
what viruses are in this family
envelope?
genome structure
capsid symmetry
A

rabies

yes envelope
-ssRNA linear
helical capsid

21
Q
filoviruses:
what viruses are in this family
envelope?
genome structure
capsid symmetry
A

ebola/marburg hemorrhagic fever

yes envelope
-ssRNA linear
helical capside

22
Q
arenaviruses:
what viruses are in this family
envelope?
genome structure
capsid symmetry
A

LCMV- lymphocytic choriomeningitis virus
lassa fever encephalitis-rodents spread

yes envelope
-ssRNA circular (2 segments)
helical capsid

23
Q
bunyaviruses:
what viruses are in this family
envelope?
genome structure
capsid symmetry
A

Hantavirus- hemorrhagic fever, pneumonia, cramps, muscle aches, pulmonary edema, occurs in the “4 corners” of US

yes enveloped
-ssRNA circular with 3 segments
helical capsid

24
Q
delta virus:
what viruses are in this family
envelope?
genome structure
capsid symmetry
A

Hep D virus

yes enveloped
-ssRNA circular

25
Q

so what of the RNA viruses have segments (4)

A

reovirus (rotavirus)
orthomyxovirus (influenza)
arenaviruses (lassa fever & LCMV)
bunyaviruses (hantavirus)