Virus and Phage 5 (2) Flashcards
Describe how HIV transmission occurs
When infected blood, semen, or vaginal secretions come in contact with mucous membranes or broken skin
What was HIV originally known as?
Simian immunodeficiency virus (SIV)
How many major families of HIV are there?
Three
What are two weak points of HIV that can be targeted?
Reverse transcriptase
HIV intergrase
Describe HIV fusion inhibitors
It is an entryway inhibitor that stops the viruses escape from the endosome
Why has the search for an HIV vaccine been ineffective?
Because HIV has a high mutation rate
What two components are needed in HIV vaccines?
1 Needs to produce antibodies that bind and neutralize virus particles
2 T-cells that recognize and kill infected host cells
HIV is managed through ___ therapy
Antiretroviral
Name the four classes of antiretroviral drugs
Entry inhibitors
Revers transcriptase inhibitors
HIV intergras inhibitors
Protease inhibitors