Virus and Phage 5 (2) Flashcards

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1
Q

Describe how HIV transmission occurs

A

When infected blood, semen, or vaginal secretions come in contact with mucous membranes or broken skin

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2
Q

What was HIV originally known as?

A

Simian immunodeficiency virus (SIV)

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3
Q

How many major families of HIV are there?

A

Three

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4
Q

What are two weak points of HIV that can be targeted?

A

Reverse transcriptase

HIV intergrase

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5
Q

Describe HIV fusion inhibitors

A

It is an entryway inhibitor that stops the viruses escape from the endosome

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6
Q

Why has the search for an HIV vaccine been ineffective?

A

Because HIV has a high mutation rate

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7
Q

What two components are needed in HIV vaccines?

A

1 Needs to produce antibodies that bind and neutralize virus particles
2 T-cells that recognize and kill infected host cells

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8
Q

HIV is managed through ___ therapy

A

Antiretroviral

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9
Q

Name the four classes of antiretroviral drugs

A

Entry inhibitors
Revers transcriptase inhibitors
HIV intergras inhibitors
Protease inhibitors

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