virus Flashcards

1
Q

gen dio

A

VIH; transactivación de genes virales y celulares

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2
Q

gen nef

A

VIH; ESENCIAL!! disminuye CD4 superficie celular, facilita activación de células T, progresión al SIDA

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3
Q

gen vif

A

VIH; infectividad del virus, promueve ensamblaje, bloquea proteína antiviral celular

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4
Q

gen vpu

A

VIH; facilita ensamblaje y liberación de viriones, degradación de CD4

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5
Q

gen vpr

A

VIH; transporte ADN complementario al núcleo, detención crecimiento celular, facilita replicación en MACRÓFAGOS

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6
Q

gp160 de VIH

A

se escinde en gp41 y gp120 (codificados por gen env)

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7
Q

gp120

A

se une a receptores de superficie celular y determina tropismo tisular de virus; ES RECONOCIDA POR ANTICUERPOS

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