Virsuses Flashcards
What is a virus?
viruses are noncelullar microbes.
is a genetic element that can multiply only inside a living cell.
viruses are not alive.
what is a virion?
structurally intricate extracellular form an encoded genome that allows virus to multiply.
the virion allows the virus to travel from one host cell to another
what is capsid?
is a protein shell that contains the viral genome.
what is a nucleocapsid?
the inner structure of nucleic acid plus capsid plus capsid protein in envelope viruses,
what is a lytic pathway?
the virus redirects the host cell’s metabolism from growth to support virus multiplication and the assembly of new virions.
what is bacteriophage?
Bacterial viruses.
what is a capsomers?
a number of individual protein molecules which the capsid is composed of.
do viruses carry metabolic processess?
No
what are the 5 steps of viral replication?
1 attachment
- penetration of viral nucleic acid
- synthesis of new viral nucleci acid and proteins
- assembly and packaging of new viruses
- cell lysis and release of new virions
what is maturation phase?
begins as newly synthesized viral genomes become packaged inside their capsids.
what determines host specifity?
attachment
what is a temperate virus?
a virus whose genome can replicate along with that of its host without causing cell death,
what is a virulent virus?
a virus that lyses, or kills, the host cell after infection
what are key differences between eukaryotic and bacterial viruses?
(1) the entire virion of eukaryotic viruses enters the host cell,
2, eukaryotic cells contain a nucleus, where many (but not all) viruses replicate,
(3) in some eukaryotic cells, membrane-bound “viral factories,” also known as viroplasms, form to increase the rate of virion assembly and protect the process from host defenses
how does the animal virus enter the host cell?
entry into a host cell generally occurs by fusion with the cytoplasmic membrane or by endocytosis
where does viral replication happen in animal cell?
nucleus
what is the lysogenic cycle?
- attachment and penetration are identical to virulent viruses.
2.
what are the outcomes of viral infection?
A virulent infection (or lytic infection) results in lysis of the host cell;
in a latent infection, the viral DNA exists in the host’s genome as a provirus
can convert a normal cell into a tumor cell,
MOLECULAR BIOLOGY AND DNA REPLICATION
WHAT IS A GENE?
the functional unit of genetic information.
WHAT IS A GENOME?
total complement of genetic elements.
WHAT IS THE FUNCTION OF THE DNA WHAT DOES IT CARRY?
WHAT IS THE FUNCTION OF RNA WHT DOES IT CARRY?
DNA carries the cell’s genetic blueprint .
RNA, produced in transcription, carries a copy of this blueprint.
WHAT IS A NUCLEOTIDE?
WHAT ARE THE THREE COMPONENTS OF NUCELOTIDES?
The monomers of nucleic acids.
has three components: a pentose sugar (either ribose in RNA or deoxyribose in DNA), a nitrogenous base, and a molecule of phosphate,
IS DNA DOUBLE STRANDED?
YES
DNA is double-stranded, the strands being held together by hydrogen bonds between the bases in the two strands