Virology Mneumonics

Question 1

Emergency Care Plan

What capsids protect the internal viral structure from

Answer 1

Enzymatic damage
Chemical damage
Physical Damage

Question 2

Sharon Needles never Misses a full English (SNME)

Covid structures

Answer 2

Spike protein
Nucleocapsid
Membrane
Envelope

Question 3

Heidi In Closet Eats (HICE)

Viral morphologies

Answer 3

Helical
Icosahedral
Complex
Envelope

Question 4

Coco explored while Alaska untucked

Virion assembly checkpoints

Answer 4

Correctly assembled
Escape the cell in which they are assembled
Withstand the extra cellular environment
Attach and enter another cell
Uncoat and release their viral genome

Question 5

APUTTGAR

Steps of viral replication

Answer 5

Attachment
Penetration
Uncoating
Transcription
Translation
Genome replication
Assembly
Release

Question 6

Radiologists Telephone General Surgeons

Why so many viruses are icosahedral

Answer 6

Resistance to shear force
tight packing of genome
Genetic economy
Structural strength

Question 7

The two pathways of viral entry

Answer 7

Endosomal fusion
Surface fusion

Question 8

Information encoded in viral genomes
(Rupaul adore Raja Darienne Lake Shangela)

Answer 8

Replication of viral genome
Assembly and packaging of the genome into viral particles
Regulation and timing of the replication cycle
Defeating host defenses
Spread to other cells and hosts

Question 9

RNA guided cleavage steps of foreign viral DNA
(General ledger review)

Answer 9

Guide RNA transcribed from CRISPR array on bacterial genome

Loaded onto Cas9 nuclease

RNA guides Cas9 enzyme to cut homologous incoming viral dsDNA

Question 10

How does crispr protect bacteria from a viral attack (think CIT high school)

Answer 10

Cutting of foreign viral DNA

Insertion of DNA as a novel spacer in array

Transcription of the array creating RNAs that target the incoming viral DNA