Virology Flashcards by Victor Lu

Groups 1+2+7 (ALL DNA viruses):

HHAPPPy:
Hepadna (group 7)
Herpes, adeno, papovavirus, pox (all group 1)
Parvo (group 2)

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Group 3

Rotavirus + blue tongue virus

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Groups 4 and 6

I went to a RETRO (group 6) TOGA party, where I drank FLAVoured CORONA and ate CALIfornia PICkles (all group 4).

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Group 5

FORP

filo: Ebola
orthomyxo: Influenza A
rhabdo: Rabies
paramyxo: Measles, Mumps

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Picornarvirus

FARP (FMDV, hep A, Rhino, Polio)

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Flavivirus and Togavirus

hep C virus, Rubella, Dengue, Yellow fever, Zika

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Poxvirus

On my Mark, Vroom Vroom

Orf, Myxoma, Vaccinia, Variola

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Herpesvirus

‘Vacate her’ (VEC 8 Her)

Varicella-zoster, Epstein-Barr, Cytomegalovirus, human herpesvirus 8, Herpes simplex.

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Type of capsid

ALL groups 1,2,3,4,7 viruses have icosahedral capsid, apart from tobacco mosaic virus, poxvirus (complex capsid), coronavirus.

ALL group 5 viruses + coronavius + tobacco mosaic virus have helical capsid. Group 6 viruses have 100nm capsid.

Herpesviruses + poxviruses have envelope.

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Physical barriers against pathogens

MS GIRL

Mucous secretions, Skin, Gastric acid, Iron limitation, Resident microflora, Lysosomes

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Blood iatrogenic (site of entry)

BIC

HBV, HIV, HCV

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Blood biting insects (site of entry)

bite Your Blue Dumpling + arboviruses

blue tongue virus, yellow fever, dengue

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Genital tract (site of entry)

SIP 6+11

HSV, HIV, HPV 6+11

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Skin (site of entry)

PRS

HPV, Rabies, HSV

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Alimentary canal (site of entry)

A POlish ADvertisement + rotavirus

HAV, Poliovirus, Adenovirus

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Respiratory system (site of entry)

Very good MMR ADvertisement + rhinovirus + influenza

VZV, Measles, Mumps, Rubella, Adenovirus

Oropharynx (site of entry)

Mega BarS

cytomegalovirus, Epstein-Barr, HSV

Conjunctiva (site of entry)

HSV

Blood (site of exit)

Yellow BIC

Yellow fever, HBV, HIV, HCV

Genital tract (site of exit)

BIP 16+18 (HBV, HIV, HPV 16+18)

Skin (site of exit)

M&S ViP on days 6+11

Measles, HSV, VZV, HPV 6+11, obvious that HIV doesn’t exit through skin

Alimentary canal (site of exit)

A POlish Cat + rotavirus

HAV, Poliovirus, Calicivirus

Respiratory system (site of exit)

Very VARIable Monday + rhinovirus + influenza

VZV, Variola, Measles

Saliva (site of exit)

MUM Rummaged for her Mega Bar (Mumps, Rabies, cytomegalovirus, Epstein-Barr virus)

Placenta (site of exit)

RUde Mega Zika virus | rubella, cytomegalovirus, Zika

Breast milk (site of exit)

Cytomegalovirus

HCMV entry routes + exit routes

Sexy POO Better Come + My Penis is So Good entry: Sexual transmission, Perinatally via birth canal (together with herpes simplex, HBV is via blood contact at birth) and breast milk, Oral, Organ transplant, Blood transfusion, Congenitally via placenta. exit: Mammary glands, Placenta, Salivary gland, Genital tract.

Live Vaccines

"Live! One night only! See Small Yellow Chickens, Canines, Marek's turkeys, Pigs get VACCINIAted with Sabin's and MMR!" RoAR! Vaccinia virus for smallpox (caused by variola virus), Yellow fever virus Chickenpox (VZV) Canine distemper virus Turkey herpes virus for Marek's disease virus Pig herpes virus/pseudorabies virus (genetically engineered live attenuated) Sabin's for polio Measles, Mumps, Rubella Rinderpest virus Hepatitis A Rabies (genetically engineered live vaccinia virus with rabies glycoprotein gene) All are attenuated mutants of the wild type apart from vaccines for variola virus, Marek's disease virus, and rabies virus for which live related viruses are used.

Dead Vaccines

RIP Always, Forever Best Pals and Mates ``` Rabies (killed or immunoglobulin) Influenza (subunit) Polio (Salk) HAV Foot and mouth disease virus Hepatitis B virus (genetically engineered subunit or immunoglobulin) Human papillomavirus types 16+18 (genetically engineered subunit) Measles (maternal antibodies via milk) ``` All are killed whole viruses, otherwise mentioned in brackets. Dead vaccines mostly induce antibody but NOT cellular immunity.

Enveloped viruses

All group 5,6,7 + herpesvirus, poxvirus, flavivirus/togavirus, coronavirus.