Virology

Question 1

DNA virus that doesn’t replicate in nucleus

Answer 1

poxvirus

Question 2

RNA virus that jdoesn’t replicate in the cytoplasm

Answer 2

influenza virus and retrovirus

Question 3

what virus gets envelope from nuclear membrane

Answer 3

herpes virus

Question 4

nonlinear DNA virus

Answer 4

papilloma and polyoma (circular and supercoiled + hepadna (circular incomplete)

Question 5

How is poxvirus weird and what does this mean about infectivity

Answer 5

Its the only one that replicates in cytoplasm. Uses its own DNA-dependent RNA polymerase. Its the reason it can’t infect as a naked viral genome.

Question 6

Why can’t hepadnavirus infect with just viral genome

Answer 6

has a reverse transcriptase

Question 7

How is parvovirus unique

Answer 7

Only ss DNA. Smallest. ONly has parvovirus

Question 8

What area causes splenomegaly in EBV

Answer 8

periarterial lymphatic sheath

Question 9

EBV generalized lymphadenopthy is hyperplasia of what?

Answer 9

Paracortex

Question 10

Owl eye inclusion

Answer 10

CMV

Question 11

CMV latent in

Answer 11

mononuclear cells

Question 12

Multinucleated giant cell

Answer 12

HSV 1,2 VZV - also see intranuclear inclusions

Question 13

Ways to identify HSV

Answer 13

Viral culture of skin/genitalia
CSF PCR
Tzank test of opened skin vesicle