Viral resp infections Flashcards
What are the symptoms of the common cold?
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How are common cold symptoms different than LRT infection?
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What viruses cause the common cold?
Rhinovirus
Coronavirus
What viruses cause more serious resp tract infections
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What are the Epidemiology any symptoms of SARS and MERS?
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What are the typical symptooms of Influenza?
fever, myalgia, headache, shaking, chills and cough peaking between 3-5 days
cough, fatigue and weakness may last 2-6 wks
What 4 patient groups are associated with increased risk for influenza complications?
Diabetics
Children
What differentiates the 4 different influenza antiviral agents?
Zanamivir and Oseltamivir for Type A and B
Zan = Inhalation
Osel = Oral
What is the difference between bacterial pneumonia following influenza and and 1^ influenza pneumonia?
Bact after viral:
Biphasic, 7 day onset
Bacterial Cells on gram stain
1^ inf pnu
Progressive worsening
1-4 day onset
no sputum gram stain
What are the 3 categories of influenza vaccines and what are their eligibiltiy reqirements ?
Live attenuated- healthy non-pregnant 2-49yo Inactivated (chronic med cond) -IM->6mon -ID-18-64yo Recombinant (18-49)
What are the Clinical presentation and symptoms of CMV pneumonitis?
Owl’s Eye inclusions charicteristic of CMV on smear
Malaise, fatigue, spiking fever, mild dyspnea,
Pneumonitis: Interstitial infiltrates, and Hypoxia
What is the incidence and transmission of CMV?
Immuno compromized individuals
-Transplant Recipients
-Adv HIV infections
Asymptomatic in Imm-competent
Can be transmitted intrauterine, through breast milk, sexual transmission, saliva and genital secretions, blood, via transplanted organs
What is the use of ^Gancyclovir, ^valacyclovir, foscarnet, Cidofovir in treatment and prevention of CMV?
Gan: DNA Polymerase is the target
Viral Thymidine Kinase targets the drug
What is the Respiratory disease associated with HSV?
Pneumonitis
What is the Respiratory disease associated with VZV?
Secondary Bacterial Infections
