Viral Infections

Question 1

Verruca vulgaris

Answer 1

common wart, 70%, HPV 2 and 4, periungal/subungal

Question 2

verruca plana

Answer 2

HPV 3 and 10, small flat lesions, koebnerization, spontaneous remission, linear

Question 3

Filiform or digitate warts

Answer 3

HPV 6 and 11, face, neck, genital region, finger like projections

Question 4

Verruca plantaris

Answer 4

HPV1 and mosaic HPV 2, sole of foot

Question 5

How to diagnose warts

Answer 5

epidermal hyperplasia, inclusion bodies, papillomatosis

Question 6

Molluscum contagiosa general facts

Answer 6

DNA pox virus, common in kids, highly infections and communicable, transmission by direct contact, face, upper body and LE

Question 7

Molluscum Contagiosum lesions

Answer 7

dome shaped papule with central umbilification, pearly white, self limiting 2-9 months, rarely feet

Question 8

Molluscum Contagiosum dx

Answer 8

KOH wet mount shows molluscum bodies, Tzanck test demonstrates ground glass inclusion bodies

Question 9

Herpes simplex characteristics and forms

Answer 9

DNA virus, primary forms: two forms appear on foot-herpetic whitlow and eczema herpeticum,

Question 10

Primary HSV clinical course and lesion details

Answer 10

virus entered skin-peripheral nerve-DRG (life long latent infection), sudden onset itching and burning, 5-7 days small grouped vesicles on erythematous base, dermatomal distribution, painful

Question 11

HSV clinical course-systemic sx

Answer 11

3-5 days after lesions, febrile, associated lymphangitis, mistaken for bacterial infection, healing occurs in 7-10 days

Question 12

HSV dx

Answer 12

tissue culture and clinical suspicion and course mainly

Question 13

Herpes zoster characteristics

Answer 13

shingles, varicella virus, reactivation of latent infection, most over 45 yo

Question 14

Herpes zoster clinical course

Answer 14

pain localized to area of one or more dorsal roots (thoracic, cervical and trigeminal N most often, 2-5 days later erythematous papules following one or two dermatomes, rapid progression to vesicular then pustular eruption

Question 15

Herpes zoster distribution and other sx

Answer 15

usually unilateral distribution, paresis of involved m groups not uncommon, enlarged regional nodes, recovery in 2-4 weeks

Question 16

Herpes zoster dx

Answer 16

tzanck test, ballooning degeneration, acantholysis with resultant vesicle formation

Question 17

hand foot mouth virus and clinical course

Answer 17

Coxsackie A16 and A5 virus, flu like, sore throat before lesions, painful stomatitis, acute vesicular eruption, light grey vesicles in red areola, dorsal and perinatal location (palms/soles), 4-7 day duration

Question 18

Foot mouth disease

Answer 18

non human picornaviruses, contact with infected animal, flu like sx, swelling itching and burning, vesicular eruption of oral MM, palms, soles, interdigital sites, progress to ulcerations