Viral Hepatitis

Question 1

4 phases of infectious hepatitis

Answer 1

1) Viral replication phase
2) Prodromal phase
3) Icteric phase
4) Convalescent phase

Question 2

Phase wherein patient is asymptomatic but serologic and enzyme markers of hepatitis are present

Answer 2

Viral replication phase

Question 3

Phase wherein patient presents with gastroenteritis-like symptoms

Answer 3

Prodromal phase

Question 4

Phase wherein patient may note dark-colorer urine, pale stools, icterisia, and RUQ pain; on PE, hepatomegaly may be appreciated

Answer 4

Icteric phase (usually within 10 days of initial symptoms)

Question 5

Symptoms, including icterus, resolve, and liver enzymes return to normal

Answer 5

Convalescent phase

Question 6

Serum marker required for the diagnosis of acute hepatitis B infection

Answer 6

Anti HBcAg IgM

Question 7

Hallmark of acute viral hepatitis

Answer 7

Striking elevation in serum transaminase activity, especially ALT (up to >100-fold)

Question 8

Important diagnostic test for hepatitis per phase: Incubation

Answer 8

HBsAg

Question 9

Important diagnostic test for hepatitis per phase: Prodrome/acute disease

Answer 9

HBsAg (Anti-HBc)

Question 10

Important diagnostic test for hepatitis per phase: Early convalescence phase

Answer 10

Anti-HBc

Question 11

Important diagnostic test for hepatitis per phase: Late convalescence phase

Answer 11

Anti-HBs (anti HBc)