Viral Hepatitis Flashcards
what is viral hep?
inflammation of liver due to hepatitis virus
mode of transmission of hep A
oral and fecal
mode of transmission of hep E
oral and fecal
mode of transmission of hep B
bodily fluids - needles, transfusions, sexual, placenta
mode of transmission of hep D
bodily fluids - needles, transfusions, sexual, placenta
REQUIRES COINFECTION WITH HEP B VIRUS
mode of transmission of hep C
bodily fluids - needles, transfusions, sexual, placenta
what risk factors are associated with getting Hep A virus and Hep E virus?
visiting or living in a low-income country w/ poor sanitation and water access
What s/s could you see from hepatitis infection?
jaundice
viral infection s/s: fever, malaise, fatigue, anorexia, nausea, vomiting, diarhea, abdo pain
dark coloured urine (bili in urine)
pale cauliflower stool
RUQ pain bc liver enlargement
which hepatitis viruses can become chronic?
HCV - 50% of the time
HBV - 10% of the time
what complications can occur with chronic hepatitis?
cirrhosis and HCC
why can cirrhosis occur in chronic hepatitis?
because chronic inflammation in the liver results in irreversible fibrosis and scarring of the tissue and nodule formation where regeneration tries to occur
which hepatitis viruses have immunizations? and when should you get them?
hep a - get before travel, doesn’t give long term/standing immunity
hep b - get as a part of childhood vaccinations ➔ series of 3 shots of the antibody
what is serum sickness? (hep b)
it is an immune-complex mediated hypersensitivity rxn
presents with fever, rash, and joint pains
typically resolves when jaundice appears which is when they present to hospital
which hepatitises require treatment (and what is it)? vs is self-limiting?
self-limiting: hep a, b, c
HCV: direct-acting antiviral pills
what ix would you order for hep A
HAV antibody (IgM acute infection/recent infection; IgG past infection)
