Viral Hep Flashcards
How is hepatitis A spread?
Faeco-oral
Poor hygiene/overcrowding
Does Hep A lead to chronic?
Nah
Main age group that Hep A affects?
children - young adults
Diagnostic tests for Hep A ?
high ALT/ AST
clotted blood of HAV IgM
How is Hep B spread?
Blood borne/ sexually transmitted
Whtat group of people does Hep B affect?
Children of infected moms, PWID, MSM, high prevalence area
Name the suppressive therapies used in Hep B
tenofovir, entecavir
What can be given in Hep B to reduce inflammation?
PegIFN-alpha (48 week course)
Is hep B chronic or acute?
can be both, chronic is > 4 weeks
Which hepatitis B markers are usually present in highly infectious individuals?
HBeAg
If a pt is pregnant and has Hep B and also has cirrhosis, what medication can you give?
TENOFOVIR
How is Hep C spread?
Blood borne spread (PWID, transfusions/ surgeries)
Is Hep C chronic or acute?
CHRONIC (HCV RNA >6 months)
Diagnostic markers for Hep C?
- HCV IgG
- HCV RNA by PCR
What medication is given for pts with Hep C?
DAA
After giving DAA in Hep C, after how long will you re-evaluate the pt to see response to treatment?
12 weeks
Hepatitis D is only found with hepatitis B infection. True/False?
TRUE
Diagnostic marker of Hep D?
HDV RNA by PCR
Treatment for Hep D?
Pegylated INF-alpha (48 wks)
Bulvenitide
How is Hep E spread?
Faeco-oral
(zoonotic - pig)
Is Hep E acute or chronic?
Acute - rarely chronic
Diagnostic marker for Hep E?
HEV IgM
Which type of Hep causes acute?
A, B, E
Symptoms of AVH?
abdominal pain, nausea, vomiting, jaundice, diarrhoea
Treatment for AVH and diagnosis
T: supportive, antivirals on in Hep B if hepatic failure
D: raised ALT + AST, may have raised bilirubin, normal Alk Phos/ GGT
REVIEW NOTION NOTES WEEK 4 FOR CHRONIC VH
