Viral Hep

Question 1

How is hepatitis A spread?

Answer 1

Faeco-oral

Poor hygiene/overcrowding

Question 2

Does Hep A lead to chronic?

Answer 2

Nah

Question 3

Main age group that Hep A affects?

Answer 3

children - young adults

Question 4

Diagnostic tests for Hep A ?

Answer 4

high ALT/ AST
clotted blood of HAV IgM

Question 5

How is Hep B spread?

Answer 5

Blood borne/ sexually transmitted

Question 6

Whtat group of people does Hep B affect?

Answer 6

Children of infected moms, PWID, MSM, high prevalence area

Question 7

Name the suppressive therapies used in Hep B

Answer 7

tenofovir, entecavir

Question 8

What can be given in Hep B to reduce inflammation?

Answer 8

PegIFN-alpha (48 week course)

Question 9

Is hep B chronic or acute?

Answer 9

can be both, chronic is > 4 weeks

Question 10

Which hepatitis B markers are usually present in highly infectious individuals?

Answer 10

HBeAg

Question 11

If a pt is pregnant and has Hep B and also has cirrhosis, what medication can you give?

Answer 11

TENOFOVIR

Question 12

How is Hep C spread?

Answer 12

Blood borne spread (PWID, transfusions/ surgeries)

Question 13

Is Hep C chronic or acute?

Answer 13

CHRONIC (HCV RNA >6 months)

Question 14

Diagnostic markers for Hep C?

Answer 14

1. HCV IgG
2. HCV RNA by PCR

Question 15

What medication is given for pts with Hep C?

Answer 15

DAA

Question 16

After giving DAA in Hep C, after how long will you re-evaluate the pt to see response to treatment?

Answer 16

12 weeks

Question 17

Hepatitis D is only found with hepatitis B infection. True/False?

Answer 17

TRUE

Question 18

Diagnostic marker of Hep D?

Answer 18

HDV RNA by PCR

Question 19

Treatment for Hep D?

Answer 19

Pegylated INF-alpha (48 wks)
Bulvenitide

Question 20

How is Hep E spread?

Answer 20

Faeco-oral
(zoonotic - pig)

Question 21

Is Hep E acute or chronic?

Answer 21

Acute - rarely chronic

Question 22

Diagnostic marker for Hep E?

Answer 22

HEV IgM

Question 23

Which type of Hep causes acute?

Answer 23

A, B, E

Question 24

Symptoms of AVH?

Answer 24

abdominal pain, nausea, vomiting, jaundice, diarrhoea

Question 25

Treatment for AVH and diagnosis

Answer 25

T: supportive, antivirals on in Hep B if hepatic failure

D: raised ALT + AST, may have raised bilirubin, normal Alk Phos/ GGT

Question 26

REVIEW NOTION NOTES WEEK 4 FOR CHRONIC VH