Viral, fungal and parasitic skin infections Flashcards
What are the characteristic signs of Herpes Simplex Virus?
Primary and recurrent vesicular eruptions
Where are HSV eruptions most commonly found?
Orolabial and Genital regions
How do these hsv strains spread?
HSV-1: contact with contaminated secretions
HSV2: sexual contact
When do symptoms of HSV start?
3-7 days after exposure
What are HSV symptoms preceded by?
Malaise, general unwellness w/ lethargy
Anorexia,
Lymphadenopathy, swollen lymph nodes
Describe the vesicles in HSV
Painful vesicles with erythematous base, ulceration and crusting
What medical emergency cutaneous sign can be caused by HSV?
Eczema Herpeticum
can spread to the brain and cause fatal encephalitis
What are the systemic manifestations of HSV, and its prevalence?
Aseptic meningitis (up to 10%)
Orolabial vs genital symptoms
orolabial, often asymptomatic, painless
genital, painful and may lead to urinary retention
Describe the vesicles in eczema herpeticum
Monomorphic, punched out erosions
What is herpetic whitlow?
Infection of digits - causing pain and swelling
common in children and mistaken for dactylitis
What manifestation of HSV is more common in childbirth?
Neonatal HSV infection
vesicles localised in scalp/trunk
What are the complications of Neonatal HSV
Encephalitis, 50% mortality w/o treatment
survivors may have serious neuro deficits
Treatment for neonatal HSV
IV antivirals
Who can severe, chronic HSV affect?
Immunocompromised patients (HIV, transplants)