Viral Etiology of tumors

Question 1

Cervical cancer is linked to what virus

Answer 1

HPV

Question 2

HTLV 1 infects what lymphocytes

Answer 2

CD4+ T lymphocytes

Question 3

HTLV 1 retrovirus can be transmitted through

Answer 3

Blood transfer
Breast milk

Question 4

HTLV 1 appears to drive cell growth through the expression of ………….. in latently infected cells

Answer 4

Tax

Question 5

EBV is found in what cancers

Answer 5

Burkitt’s lymphoma
Nasopharyngeal carcinoma

Question 6

Which cancer can be found in patients with AIDS

Answer 6

Kaposi’s sarcoma

Question 7

Kaposi tumors generally appear on

Answer 7

Upper body
Oral areas

Question 8

What virus causes hepatitis in humans

Answer 8

HBV

Question 9

List the genes of the HBV genome

Answer 9

Pol
Env
Pre-core
X

Question 10

List the main risk factors for the development of Hepatocellular carcinoma

Answer 10

HBV
HCV
Alcoholism
Aflatoxin intake

Question 11

Viral families associated with Viral Hemorrhagic fever

Answer 11

Arenaviridae
Filoviridae
Flaviviridae
Bunyaviridae
Togaviridae

Question 12

Arenaviridae transmission and human infection

Answer 12

•Transmitted through rodents
•Human infection-Excreta contact, contaminated materials, aerosols

Question 13

Incubation period of Arenaviridae

Answer 13

2-21days

Question 14

When do Fever and malaise occur in arenaviridae infection

Answer 14

2-6days

Question 15

The hemorrhagic stage of Arenaviridae includes

Answer 15

Hemorrhage, Leukopenia, Thrombocytopenia

Neurological signs

Question 16

Bunyaviridae transmission

Answer 16

Arthropods (except Hantavirus)

Question 17

RVF is transmitted by

Answer 17

Aedes mosquito

Question 18

CCHF is transmitted by

Answer 18

Ixodid tick

Question 19

Hantavirus is transmitted by

Answer 19

rodents

Question 20

Incubation period of RVF

Answer 20

2-5days

Question 21

Incubation of CCHF

Answer 21

3-7days

Question 22

Incubation period of Hantavirus

Answer 22

7-21 days

Question 23

Rate of abortion in animals afflicted with viruses from Bunyaviridae

Answer 23

100%

Question 24

Reservoir of Filoviridae transmission

Answer 24

Unknown

Question 25

Filoviridae transmission

Answer 25

•Intimate contact
•Nosocomial transmission
•Aerosol transmission

Question 26

The most severe hemorrhagic fever

Answer 26

Filoviridae in Humans

Question 27

Incubation period of Filoviridae

Answer 27

2-21 days

Question 28

Death due to filoviridae in humans could result in what day

Answer 28

7-11

Question 29

What virus of filoviridae causes Ebola in non human primates

Answer 29

Ebola Reston
Mortality-82%

Question 30

Transmission of yellow fever and dengue viruses

Answer 30

Aedes aegypti
•Sylvatic(jungle) cycle
•Urban(epidemic) cycle

Question 31

Transmission of Kasanur forest virus

Answer 31

Ixodid tick

Question 32

Transmission of Omsk Hemorrhagic Fever virus

Answer 32

Muskrat urine, faeces, blood

Question 33

Incubation period of Yellow fever

Answer 33

3-6days

Question 34

Incubation period of Dengue Hemorrhagic Fever

Answer 34

2-5 days

Question 35

Ribavirin treatment of VHF

Answer 35

Arenaviridae and Bunyaviridae only
Effective in some individuals
Not approved by FDA

Question 36

Convalescent phase plasma is used in the treatment of

Answer 36

Argentine HF
Bolivian HF
Ebola

Question 37

The most stable VHF in liquid or frozen states

Answer 37

Rift Valley fever

Question 38

VHFs pose a threat as aerosolized agents T/F

Answer 38

T