Viral Classification And Structure Flashcards
Virus
Small obligate IC agents that cam replicate only within living susceptible cells
Virus structure simply
Genetic info in a package to protect it from the enviro and enable entry into host cell for replication
Package cont
Pro and can sometimes cont lipid
The pros may incl enzymes as well as having structural fx and potentially other biological fxs to assist with repl
Rely on host cell for translation and maybe transcription mech
Capsid structure
Pro shell surrounding the nucleic acid
Made up of pro units called capsomeres
What is the nucleocapsid
Combo of nucleic acid and capsid
Envelope
Capsid may or may not be surrounded by a lipid bilayer mem (envelope)
Enveloped viruses have glycoproteins encoded by the virus present in the mem
Virion
A virus particle
2 criteria for classification
Structure of virus (both morphology and biochem comp
Mode of replication
Viral classification diff to animal, plant etc class
Virus only have family
Subfamily and genus levels and individual mem of genus is a strain or species or type
Some key criterion for viral classification
DNA or RNA genome (1st criterion)
Refined further by double or single stranded
And one piece v segmented genome
Also enveloped v non-enveloped
Enveloped DNA viruses
Herpes
Hepadna
Pox
Enveloped rna viruses
Orthomyxo Bunya Paramyxo Corona Arteri Retro Filo Rhabdo
Naked dna viruses
Adeno
Papo
Parvo
Circo
Naked rna viruses
Calici
Picorna
Reo
Herpesviridae
Ovine herpes virus 2 cause malignant catarrhal fever in cattle but is asymptom in sheep all sheep have after about 3 mnth old
Poxviridae
Dumbell shaped core Myxomatosis Orf Smallpox 2or 3 mems
Orthomyxo
Flu
Classify by H and N surf glycopros
Paramyxo
Newcastle disease
Measles
Rinderpest
Coronaviridae
FIV
Arteriviridae are related but with a smaller genome
Retroviridae
Feline leukaemia
Ovine pulmonary adenomatosis
Filoviridae
Ebola
Filamentous
Rhabdoviridae
Rabies
Rod shaped
Adenoviridae
Cause of some common colds
Parvoviridae
Single stranded bases
V small
Feline panleukopaenia
Circoviridae
Small
Single stranded Dna
Porcine post weaning multi system wasting syndrome
Calicivirus
Rabbit haemmorrhagic fever
Feline calicivirus
Picornaviridae
FMD
Polio fever
Reoviridae
Bovine rotavirus
Bluetongue
Baltimore classification
Relate viral genome to mRNA sense
Balt class 1
dsDNA
Balt class2
ssDNA
Balt class3
dsRNA
Balt class4
+ve sense ssRNa
Balt class 5
-ve sense ssRNA
Balt class 6
Retroviridae
Balt class 7
Reversiviruses (Hep B)