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Derm > Viral and fungal DSA checkpoint > Flashcards

Viral and fungal DSA checkpoint Flashcards

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Dermatology Board Prep flashcards
1
Q
  1. What is the most common clinical manifestation of sporotrichosis?
A

a. Lymphocutaneous infections

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2
Q
  1. How is sporotrichosis commonly transmitted?
A

a. Grows on plants and in the soil, gardeners

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3
Q
  1. Which pathogens can present clinically like sporotrichosis
A

a. Nontuberculous mycobacterial infection, especially M. marinum; nocardia infections; Leishmania brasilensis; tularemia

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4
Q
  1. What is an asteroid body? Which type of pathogens cause this phenomena?
A

a. Yeast are observed in patient samples with eosinophilis material radiating outwards, can occur with s. schenckii and other stuff

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5
Q
  1. If isolated from a patient biopsy, how does S. schenckii appear? How does the mold form appear?
A

a. Septate hyphae with conidia ballooning off the conidiophore

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6
Q
  1. Which condition predominantly determines if S. schenckii is in the mold or yeast form?
A

a. Temp?

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7
Q
  1. What are some of the general characteristics of Parvoviridae?
A

a. Non-enveloped, icosahedral virus, store genetic info as SS linear DNA

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8
Q
  1. What type of cells does parvovirus B19 preferentially replicate in?
A

a. Primarily in immature cells in erythroid lineage

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9
Q
  1. Which childhood disease is caused by parvovirus B19? How are the clinical manifestations of parvovirus B19 different in adults compared to children?
A

Fifths disease (erythema infectiosum)

i. Flu-like symptoms, children with facial rash
ii. Adults get arthralgia and arthritis

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10
Q
  1. Which autoimmune disease does parvovirus infections sometimes mimic in adults?
A

a. RA

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11
Q
  1. What are the consequences of parvovirus infections in patients with RBC diseases or severe immunodeficiencies? What about infections during pregnancy?
A

a. Aplastic crisis

b. Hydrops fetalis

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12
Q
  1. What are some of the common characteristics of herpesviruses?
A

a. Linear, DS DNA, enveloped virions are icosahedral

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13
Q
  1. In which type of cells do herpesviruses establish latent infections?
A

a. Neurons, peripheral sensory nerves

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14
Q
  1. Which type of molecules on host cells do herpesviruses use to enter?
A

a. Binding gags from immunoglobulin superfamily

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15
Q
  1. Where does the envelope of herpesviruses come from?
A

a. Pinching off a segment of the nuclear membrane

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16
Q
  1. What are some of the diseases commonly associated with HSV-1? HSV-2?
A

a. Gingivostomatitis, genital herpes, herpetic keratitis, neonatal herpes, herpetic whitlow, disseminated herpes infections, encephalitis

17
Q
  1. What are two common complications of genital herpes?
A

a. Aseptic meningitis and extragenital lesions

18
Q
  1. What are some of the ways neonatal herpes is contracted and what are some common symptoms of the disease?
A

a. Directly cross the placental barrier or during vaginal births
b. Skin lesions and encephalitis

19
Q
  1. Which HSV species commonly causes herpes gladiatorum? Who are the at risk groups?
A

a. HSV-1 wrestlers, MMA fighters

20
Q
  1. What is the most common cause of fatal sporadic viral encephalitis in the US?
A

a. HSV-1

21
Q
  1. Which two disease are most commonly associated with varicella-zoster virus?
A

a. Chicken pox and shingles

22
Q
  1. What are some common complications of infections with varicella-zoster virus?
A

a. Encephalitis, pneumonia, and disseminated infections

23
Q
  1. In which system are the enteroviruses commonly isolated and how are they commonly spread?
A

a. GI

24
Q
  1. Which enterovirus is the most common cause of hand-foot-and-mouth disease?
A

a. Coxsackievirus A16 and B1

b. Enterovirus 71

25
Q
  1. Which times of year are enterovirus outbreaks the most common?
A

a. Summer and fall

Derm (5 decks)

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