VIH Flashcards

1
Q

Riesgo de transmisión maternal fetal

A

13-40%

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2
Q

Diagnóstico

>18 meses- adultos

A

1- prueba rápida o ELISA

2- CONFIRMAR: Western blot o Inmunofluorescencia indirecta

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3
Q

Una vez diagnosticada

A
  • carga viral
  • conteo CD4,CD8
  • PPD
  • VDRL
  • perfil hepatitis B, C
  • aerología: CMV, T.gondii, placa tórax
  • PFH, Ego, BH, QS, Perfil lípidos
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4
Q

Inició de Tx

A
CD4 <350 cel
Embarazadas 
Nefropatia asociada a VIH
PX coinfectados con HBV
Infección crónica sintomática
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5
Q

SIDA

A

presencia de >20 infecciones oportunistas o Ca relac a VIH

Ly <200

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6
Q

Profilaxis postexposicion

A
  • Contacto mucosas o vía parenteral <72h

- contacto laboral <4h : IDEAL

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7
Q

Clasificación clínica
A- sx retroviral agudo, fase asintomática y linfadenopatia
B- deterioro inmune no es muy grave
C- enf oportunistas: cándida esofagica

A

Inmunológico
Categoría 1) >500 LyDC4
2) 500-200
3)<200

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8
Q

Tx
2 análogos nucleosidos + 1 análogo no nucleosido ( EFV)
Ó inhibidor de la integrasa: dolutegravir

A

1) tenofovir/ emtricitabina+ efavirez
2) abacavir/ lamivudina+ dolutegravir–> ABC realizar la prueba HLAB 5701
3) Tenofovir/ Emtricitabina+ dolutegravir –> info escasa con CD4 <200

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9
Q

Cryptococcus neoformans
Meningitis
- hiperproteinorraquia
Ly , dism gluc

A

<100 Ly CD4
Tx anfotericina + 5-flucitosina
Profilaxis: fluconazol
Tinta china

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10
Q

Pneumocystis jiroveci

A

<200 Ly CD4
Dx azul de toloudina o plata de gomori
Tx: TMP- SMZ( y profilaxis cotrimoxazol )
EA: toxicidad en la med ósea

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11
Q

Toxoplasma gondii

Parasito: gato o carne cruda

A

<100 Ly CD4
TAC/ abscesos cerebrales: lesión redondeada con edema: capta contraste en anillo
Tx silfadiazina+ pirimetamina

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12
Q

M. Tuberculosis

A

<300 CD4

No dar rifampicina + Inhib proteasa( metab P450) sustituir por no análogos

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13
Q

Mycobacterium avium complex

A

<50 Ly CD4

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14
Q

CMV

A

<75-50 CD4
Retinitis: hemorragias y exudados amarillos
Tx ganciclovir

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15
Q

Tenofovir

A

EA
Osteopenia
Nefrotoxicidad

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16
Q

Abacavir

A

Riesgo de infarto en px con alto riesgo cardiovascular